Speaker 1: Step right up, ladies and gents. Tickets your tickets. The
Speaker 1: wild and materre about to begin.
Speaker 2: Tikets, tickets, get them here on the Greatest show.
Speaker 1: Welcome to Deplorable Cult Nation, Act Cloth Conspiracy Side Show Tent,
Speaker 1: the greatest freak show on Earth, where the stranger it gets,
Speaker 1: the more that it's worth. See the Curious and the Absurd,
Speaker 1: Every act you've never seen or heard. Tickets tickets against
Speaker 1: your tickets here.
Speaker 3: See the curious and the absurd, Every act you've never
Speaker 3: seen or heard.
Speaker 1: Tickets tickets tickets here.
Speaker 4: Hi, and welcome back to another episode of Deplorable Nation.
Speaker 4: I'm your host, Deplorable Janna, and today, ladies and gents,
Speaker 4: we have another banger in the Sideshow Attraction series. This
Speaker 4: is what's age got to do with it? And we're
Speaker 4: going to talk about all things wild and weird that
Speaker 4: make people rapidly age and change their appearance to like
Speaker 4: little kids or even babies looking like really old people,
Speaker 4: very wrinkly, saggy skin, the whole nine yards. This one
Speaker 4: is very odd and different. But welcome that to my
Speaker 4: wonderful bestie from the West e, my lovely other have
Speaker 4: the darling Miss Heidi from Unfiltered Rise, How are you love?
Speaker 3: Wonderful? Wonderful, Thank you for having me. Always fun to
Speaker 3: collaborate with Miss Janet. She is awesome and you guys
Speaker 3: always have to check out her work if you're watching
Speaker 3: on my show. We do some amazing things, I feel,
Speaker 3: and I think that this series has really brought to
Speaker 3: light a lot of things that really need to be
Speaker 3: in the light.
Speaker 1: Like I mean, we can't just shove.
Speaker 3: Everything under a rug and be like that never happened,
Speaker 3: Like this one's still pretty out there.
Speaker 1: It's still around.
Speaker 4: It is, it is very out there, and for the
Speaker 4: most part, I will say that the things that we're
Speaker 4: going to discuss today, they're unusual in a lot of
Speaker 4: different ways. But I've literally only seen one person in
Speaker 4: my lifetime that had any of the things that we're
Speaker 4: going to discuss it. Yes, yeah, so.
Speaker 1: Once, and I think they were just I didn't see
Speaker 1: them in the clinical aspect.
Speaker 3: They were just at the hospital, like going the other way.
Speaker 3: So yeah, it's a weird one. And I of course
Speaker 3: brought you some slides so we can and I have.
Speaker 1: Them at an order.
Speaker 4: I hope and prays, oh well, if it, if it happens,
Speaker 4: it happens. If it does, I'm good with that too.
Speaker 3: Whatever, right, we try to collaborate so this is an
Speaker 3: easier time, so Janet doesn't have to go all over
Speaker 3: the universe with her stuff because it's a little daunting.
Speaker 4: May she has a couple of pages of notes on this.
Speaker 3: Yes, she's like, hold on a minute, hold on a second,
Speaker 3: and then I mess her all up.
Speaker 1: And maybe I've.
Speaker 4: Witched a page twenty seven in my notes.
Speaker 3: My gosh, and I tried to do these a little
Speaker 3: bit in order, and I'm so can you see this.
Speaker 1: Baby? And this is the cutest little old man I've
Speaker 1: ever seen.
Speaker 4: Yeah, and some of these things are going to be crazy.
Speaker 4: Some of the pictures may or may not be upsetting
Speaker 4: to people. Again, disclaimer at the top of the show,
Speaker 4: we are not making fun. Even if we make silly
Speaker 4: comments or say a stupid joke, we are not making fun.
Speaker 4: We are trying to shed light on conditions that not
Speaker 4: only were in the sideshows and the freak shows back
Speaker 4: in the day when it was popular, but also people
Speaker 4: that you may encounter out in public. And if you
Speaker 4: have the knowledge of what something could be, then maybe
Speaker 4: your face won't say at all if you know what
Speaker 4: I'm saying.
Speaker 3: Because if you've seen a little baby that looked like
Speaker 3: a wrinkly old man, you might be startled unless you
Speaker 3: know what it is.
Speaker 1: And that's what we're here to tell you about today.
Speaker 4: So the first thing that we're going to talk about
Speaker 4: today is called progeria. This to me is such a
Speaker 4: fascinating topic to cover because it is rare genetic thing
Speaker 4: that you don't see very often. It's like one and
Speaker 4: twenty million births, so uber rare that you see this.
Speaker 4: That's why I've never seen anybody with this condition in person.
Speaker 4: Have I seen them in shows, yes, but in person no.
Speaker 4: So what progeria is. It's also called Hutchinson Guilford progeria syndrome,
Speaker 4: and it is the thing that's closely linked to very
Speaker 4: untimely aging and so, like I said, it's a very
Speaker 4: rare genetic thing. And it has to do with the
Speaker 4: gene that makes a protein called lamon A, and that
Speaker 4: is important for maintaining the cell's nuclear structure. So like
Speaker 4: the roundness of the structure of the cell, and so
Speaker 4: because the cell can't maintain you know, size, shape, things
Speaker 4: like that, it has mutated proteins that make the cells unstable,
Speaker 4: which is what leads to the weird like aging things.
Speaker 3: Doesn't this baby look like a little nymph for something cosmute?
Speaker 3: This is the I know, we I know, we're talking
Speaker 3: about sad things, but this baby's darling.
Speaker 4: And that's the one of the things on this that
Speaker 4: a lot of babies we're going to talk about different
Speaker 4: kinds of uh. They're called progerroid syndromes. So progeria is
Speaker 4: the first one, but there is one that affects babies.
Speaker 4: So if you have like the progeria, it's Babies usually
Speaker 4: look normal when they're born and then by age one
Speaker 4: to two that's when their symptoms appear. They have a
Speaker 4: lot of growth failure, so they're very short in stature,
Speaker 4: very low in weight, loss of body fat and muscle,
Speaker 4: lots of hair loss, and it's not uncommon to see
Speaker 4: them bald. Even eyelashes and eyebrows are gone. Like this
Speaker 4: boy that we're looking at now completely bald head. You
Speaker 4: can see the indentation where the eyebrows were, but there
Speaker 4: are no eyebrows at all. So because the protein structure
Speaker 4: and the cell is abnormal is what causes them to
Speaker 4: have age looking skin. So it's either going to be
Speaker 4: really thin so you can see through it. You can
Speaker 4: see all the veins and arteries through the skin, which
Speaker 4: kind of creepy, kind of be off putting for some people.
Speaker 4: If you've never looked closely at an old person with
Speaker 4: paper thun skin.
Speaker 1: Shows those beings so good in the saginal area.
Speaker 4: Yeah, one hundred percent, and that's it kind of becomes
Speaker 4: like transparent skin, which, like I said, I've had a
Speaker 4: lot of elderly patients that have the very transparent skin.
Speaker 4: But along with this, they get really stiff joints, they
Speaker 4: get hyptose locations all of the time. They have a
Speaker 4: really small jaw, so the jaw is disproportionate to the
Speaker 4: rest of the face. They have a what they call
Speaker 4: a pinched nose, so it looks like somebody just like
Speaker 4: had an extra heavy duty breath right strip on the nose.
Speaker 4: And like you look at.
Speaker 3: Live cuey dolls if anybody remembers Qby dolls, Yes, yeah,
Speaker 3: they look and not in a derogatory way way and
Speaker 3: not being made.
Speaker 4: So people that get progeria, the main progeria as a child, unfortunately,
Speaker 4: life expectancy for them is fourteen to fifteen years old,
Speaker 4: so not a super long time if they're lucky to
Speaker 4: their twenties. But that's with exceptional medical care. And I'm
Speaker 4: just going to throw this out there. With the quote
Speaker 4: unquote practice of medicine that we have, I can see
Speaker 4: a progeria patient being grossly misdiagnosed a lot before they
Speaker 4: finally actually figure out what it is because a lot
Speaker 4: of the symptoms that they get closely mimics some of
Speaker 4: the things that we've talked about on previous shows. So
Speaker 4: for them to you know, narrow that down.
Speaker 3: Here, especially in a mild case, because this doesn't always
Speaker 3: look like this. This can sometimes like some of these
Speaker 3: other kids in this one right here, right like this
Speaker 3: little girl looks like she may have looked semi I
Speaker 3: don't want to say normal, but like baseline, okay, yeah
Speaker 3: for a while, like she does.
Speaker 1: I mean, you know, it's not that severe and so.
Speaker 4: Yeah, yeah, and so some of these some of these children,
Speaker 4: they're they're definitely like progressive stages of this and how
Speaker 4: severe each one of them has. One of the things
Speaker 4: that they have a really hard time with is they
Speaker 4: developed arterial schulerosis, which is hardening other arteries like really
Speaker 4: early in life, so infancy or even childhood. And so
Speaker 4: it says that most of these kids, while their life
Speaker 4: expectancy is fourteen to fifteen years old, that's because they
Speaker 4: die of heart attacks and strokes more than any other
Speaker 4: population on the planet, which is frightening if you think
Speaker 4: about that, you would.
Speaker 3: Think with our extensive like changes in cardio and everything,
Speaker 3: they would have like be able to put in stents
Speaker 3: or you know, filters or whatever.
Speaker 1: But I mean, it just doesn't seem like it's changed
Speaker 1: much for these.
Speaker 4: Yeah, And I don't. And that's a good point. And
Speaker 4: I don't think because it talks about like different types
Speaker 4: of treatments that they're experimenting with or looking at or whatever.
Speaker 4: But if you have something where your genes are mutated
Speaker 4: and it's you know, affecting the nuclear structure of the cells,
Speaker 4: and it's causing you know, plaque to build up and
Speaker 4: the arteries and all of those kind of things, would
Speaker 4: a stent or any kind of cardiothoracic surgery even hold
Speaker 4: what it any?
Speaker 1: Good? Right? Right? With such thin thin Yeah? Maybe not?
Speaker 4: Yeah, they said, And that's why, like the sad thing
Speaker 4: about this is there's no cure for it. So everything
Speaker 4: that they give is just too slow progression so it
Speaker 4: doesn't get progressively worse. One of the things that they
Speaker 4: give them used to be it was marketed as a
Speaker 4: cancer drug. They do nutrition therapy, physical therapy, cardiac monitoring
Speaker 4: of course like all of the time, but it said
Speaker 4: one of the things that they're experimenting with, and you
Speaker 4: and I talked about this technology on on another episode
Speaker 4: outside of the sideshow episodes, they're doing crisper technology to
Speaker 4: see if they can take out or cut out that
Speaker 4: gene mutation that's causing.
Speaker 1: This, and we are going to fuck around and find out,
Speaker 1: you know, with all the studying I do this last week,
Speaker 1: I ran into something where somebody was saying, and this
Speaker 1: was like in a white supremacist type comment, that they
Speaker 1: almost have it figured out how to restock their race. WHOA.
Speaker 4: And like we talked about before on the Christopher episode
Speaker 4: that we did, it is gene splicing or gene editing.
Speaker 4: It started a long time ago with like dog breeders
Speaker 4: and stuff like that, where certain types of dogs like
Speaker 4: German shepherds get hip dysplasia all the time, and so
Speaker 4: the breeders can go in and can cut out that
Speaker 4: gene or whatever and make a pure line of German shepherds.
Speaker 4: So you don't think they're doing that to human beings.
Speaker 4: They've been doing that for a long time.
Speaker 3: Well, with what we were talking about before we came
Speaker 3: on Live, with the genealogy stuff they trace you know,
Speaker 3: who's up.
Speaker 1: To no good with that.
Speaker 3: And the Howard Hughes Medical Center was continued on by
Speaker 3: the Mormon mafia after Howard's death through Gay. His name
Speaker 3: is Bill Gay, And you know, it's it's very concerning
Speaker 3: knowing what we know, because why the money is there
Speaker 3: to back it, not only through grants, but the more
Speaker 3: our church is loaded.
Speaker 1: So and they were very racial.
Speaker 3: Like the other day, I was telling somebody, I said,
Speaker 3: the stuff that I'm reading here tells me that the
Speaker 3: Church didn't support the Nazis.
Speaker 1: The Church are Nazis. And I can't prove that claim.
Speaker 3: I'm just saying from what I was reading, it was
Speaker 3: a little scary.
Speaker 4: So well, and that goes to make sense because one
Speaker 4: of our episodes that we did like a really long
Speaker 4: time ago, when we were talking about like Margaret Sanger
Speaker 4: and stuff like that, you know, and and all of
Speaker 4: the com munes that they used to have like back
Speaker 4: in the day that we're breeding other too, you know,
Speaker 4: weed out basically the lesser thans of society or what
Speaker 4: they deem to be lesser society, you know, and they're
Speaker 4: wanting all white race and you know, certain eye color,
Speaker 4: certain hair color, you know, the whole nine yards. And
Speaker 4: so that kind of stuff has been not just in
Speaker 4: American culture, but every culture around the world has some
Speaker 4: type of colony commune people they push more people scientists,
Speaker 4: you know, the scientists trust the science type people that
Speaker 4: are working to eradicate things they don't agree with.
Speaker 3: And to your point, if people want to take a
Speaker 3: look see speaking of Singer, there was a big eugenics
Speaker 3: program here in Utah of all places, where they're like,
Speaker 3: have all the kids, have as many kids as you
Speaker 3: possibly can, but only certain people, right, and then they
Speaker 3: were sterilizing people that had problems and that there was
Speaker 3: this huge eugenics pilot program that took place here in
Speaker 3: Utah of all places, where it's like very you know,
Speaker 3: pro babies and not for everyone.
Speaker 4: Apparently selective pro baby yep, kind of like selective hearing.
Speaker 4: Oh did I say all that?
Speaker 3: And with people like this like this guy, he had
Speaker 3: a little documentary. It may still be out there called
Speaker 3: life according to Sam. But like if I had a
Speaker 3: baby like this, this isn't the worst thing, or like
Speaker 3: down syndrome, like they're sweet, Like they have such a
Speaker 3: limited time frame, you would be so happy for each
Speaker 3: and every day you had with them.
Speaker 1: At least that's how I would look at it.
Speaker 4: Yeah, but there are some people that couldn't do it
Speaker 4: because the looks that other people would shoot at you
Speaker 4: or whatever. And again that's just selfishness. That's your own ego,
Speaker 4: you know, getting in the way of what could be
Speaker 4: the greatest love of your life. You know what I mean.
Speaker 3: God did not give me any handicapped children because I
Speaker 3: would have gone to jail.
Speaker 1: We'll just say that some may you mean to my
Speaker 1: kid once and that would be about all.
Speaker 4: So it's the mama bear thing. It happens. Yeah. So
Speaker 4: the next thing we have is called cocaine syndrome, and
Speaker 4: that is where it's also another type of pro gyroid syndrome,
Speaker 4: but it is also neuro degenerative and has multisystems included.
Speaker 4: It affects the DNA repair of our body, so excess
Speaker 4: mutations and then you're not able to repair it from
Speaker 4: the the damage from the DNA, and so they it
Speaker 4: has to do with UV light and oxidative stress.
Speaker 1: Okay, I was just going to ask you. I'm like,
Speaker 1: which I have it?
Speaker 4: But I find which. You know, if you think about
Speaker 4: UV light is light outside, it's like from you know,
Speaker 4: fluorescent lights, it's literally all kinds of stuff. And oxidative
Speaker 4: stress is literally every day wear and tear on your
Speaker 4: body from environmental factors, the whole nine yards. And so
Speaker 4: because they can't repair anything, the cells die off at
Speaker 4: a much more rapid rate than what we normally do,
Speaker 4: which is what causes their their aging. This is the
Speaker 4: one that starts in the infants.
Speaker 1: Okay, okay, yep.
Speaker 4: And so some of the pictures if people google this
Speaker 4: and again it's called cocka.
Speaker 3: Some of them are super cute, look right, but they
Speaker 3: have weird thumbs. This is the one with the weird
Speaker 3: thumbs right sometimes.
Speaker 4: Okay, Because because this is neurodegenerative and multi system, of course,
Speaker 4: it can affect anything in your body. This picture that
Speaker 4: we're looking at right now is two sisters. One's holding
Speaker 4: the other one on her lap, and the one that
Speaker 4: she's holding on her lap literally looks like, do you
Speaker 4: ever see beetlejuice?
Speaker 1: Solly?
Speaker 3: Yeah, oh yeah, yeah, uh huh.
Speaker 4: And so this girl has a very very tiny head
Speaker 4: and her legs are bigger than you.
Speaker 1: Know, it looks like she has lymphedema. Almost doesn't.
Speaker 4: Yes, And that's it. That's pretty common as well. And
Speaker 4: so this one, like I said, it starts in infancy
Speaker 4: to early childhood, so a lot of babies can be
Speaker 4: born with this and when they're born, some of the
Speaker 4: pictures are disturbing to look at. I ran across some
Speaker 4: and I'm like, wow, that's like they look like prunes
Speaker 4: or raisins because they're so you know whatever.
Speaker 3: Yeah, yeah, So they their thumb, holy moly, yeah.
Speaker 4: This thumb. Imagine pulling your thumb backwards, like down to
Speaker 4: your wrist. This child's thumb looks like it's actually broken
Speaker 4: backwards like that. So, of course, again they've got the
Speaker 4: short stature, very low birth weight or very low weight regardless,
Speaker 4: very small heads, so microcephaly they've got, of course, the
Speaker 4: aging appearance. They've got photosensitive skin, and so they can
Speaker 4: have lesions, rashes, burns, problems with like the picture you
Speaker 4: just showed, problems with the melanocytes in your skin that
Speaker 4: give you the pigmentation and the color. So this girl
Speaker 4: has like a very spotty appearance to her face dental problems.
Speaker 4: I was, yeah, there we go. And so this girl,
Speaker 4: it looks like she had some kind of really bad
Speaker 4: like photosensitive reaction on her face where she almost got
Speaker 4: like sun poisoning or something and it damaged the color
Speaker 4: cells in the skins.
Speaker 3: So sad like this one. I mean, I think it
Speaker 3: shows it pretty good in this one. You know he's older,
Speaker 3: but yeah, look at the feet and stuff.
Speaker 4: Like, Yeah, the the toes are like very strange, like
Speaker 4: that big toe it's pointing in towards the other toes,
Speaker 4: but it's like very long and very like the bones
Speaker 4: in the feet.
Speaker 1: Are very straight, kinder like long and skinny, skinny, skinny, skinny.
Speaker 4: So this particular thing has three different classifications. They have
Speaker 4: Type one, which is early onset and unfortunately, this one
Speaker 4: is pretty progressive and death usually occurs in the first
Speaker 4: or second decade of life, so the first ten twenty
Speaker 4: years of life happens. Type two is the most severe,
Speaker 4: and it's the severe congenital form. Symptoms appear at birth.
Speaker 4: There's little to no developmental progress in the child, and
Speaker 4: they typically die by age seven.
Speaker 1: Look at that hand deformity out.
Speaker 4: So type three is the most mild form that you
Speaker 4: can get. It occurs later on in life, has slower progression,
Speaker 4: and those are usually the children that can live into adulthood.
Speaker 4: So even though they're still young, they look very elderly.
Speaker 4: They're thin, they're frail, they have sunken faces, wrinkled skin
Speaker 4: of course, the loss of muscle and fat again, and
Speaker 4: then they have the neurological decline, so it's similar to
Speaker 4: Alzheimer's or Parkinson's. And because they have a problem with
Speaker 4: their skin, they can't absorb and synthesize vitamin D properly,
Speaker 4: which is what causes all the neurological complications. And so
Speaker 4: anything neurological, like pain receptors, things like that, especially pain,
Speaker 4: is going to be really heightened in these type of children.
Speaker 4: No cure again, but again it's a genetic thing. They
Speaker 4: don't know why, so it says not any cure, but
Speaker 4: protect them from the sunlight because they're extremely photosensitive. And
Speaker 4: so if you see somebody that has a hat with
Speaker 4: a you know, the face and neck gator on long
Speaker 4: sleeve long pants, they probably have something.
Speaker 1: Don't just assume they're germaphobe in a.
Speaker 4: Week ago something related to this. So they're going to
Speaker 4: need extra and additional support again because they can't process
Speaker 4: vitamin D. So there's going to be all kinds of
Speaker 4: things that they need again because it's neurological hearing aids,
Speaker 4: visual aids, physical therapy because they can go deaf or
Speaker 4: blind because of that. Also have a lot of seizures
Speaker 4: because again NEURALI stuff is in play. And so it
Speaker 4: says again they're exploring DNA repair gene therapies for the
Speaker 4: christ technology.
Speaker 3: And here's what I love how the doctor was so
Speaker 3: nice and put a female sign on this kid right
Speaker 3: like what is wrong with you?
Speaker 4: Well, yeah, that was very nice of them too, you know,
Speaker 4: to do that. But these these kids like very sunken chest,
Speaker 4: very abnormal bones, joints, you know, all all of the things.
Speaker 4: And you know, if they're experimenting with gene therapy, and
Speaker 4: you know, gene therapy was a thing for a little while,
Speaker 4: like the monoclonal antibodies and stuff during the outbreak or
Speaker 4: planned break, but that's too like how would you give
Speaker 4: somebody something like that and have it take effect? Because
Speaker 4: they already have it. All of those cells are already damaged.
Speaker 4: How would that repair anything?
Speaker 1: I don't even know.
Speaker 3: You'd have to do it in utero at the time
Speaker 3: it's developing, I would think. And even then that's like
Speaker 3: such a high risk when you're doing in utero procedure.
Speaker 4: I just I don't know the risk for the mom,
Speaker 4: you know, let alone the baby would be tremendously off
Speaker 4: the charts. And then you don't know how the mom
Speaker 4: is going to react to injecting the baby with something. Yeah,
Speaker 4: they share it life.
Speaker 3: I mean, you know, it's not the worst thing ever,
Speaker 3: Like I mean, it's sad to watch your child go
Speaker 3: before you, But honestly, like I always think that people
Speaker 3: end up. And most of the time I see this
Speaker 3: with the parents, right that they're grateful and stuff like,
Speaker 3: they're not you know, well, most that I've ever seen
Speaker 3: with kids with issues where they're still cognitively there, it's
Speaker 3: a little bit different. Not saying the cognitive ones are
Speaker 3: worse or anything, but they're harder on people.
Speaker 1: So one hundred.
Speaker 4: And so, the next one that we're going to talk
Speaker 4: about is called Rothman Thompson syndrome. And this is another
Speaker 4: of course, rare genetic one. But this is also just
Speaker 4: in babies, and unfortunately, this is another thing that affects
Speaker 4: the DNA repair that causes instability in the genes, premature
Speaker 4: cell death, and they are at a really increased risk
Speaker 4: for cancer because it happens so young and because again
Speaker 4: it's another one of those where it has to do
Speaker 4: with not being able to repair your DNA and so
Speaker 4: this one occurs usually between in infancy, usually between three
Speaker 4: and six months old. So this little boy that we're
Speaker 4: looking at right now, he's standing in a diaper's head
Speaker 4: is very like misshaped, so it's very large at the
Speaker 4: top and the chin is very small, kind of like
Speaker 4: the other progeria symptom type things. But he has a
Speaker 4: limb abnormality in his left arm as well. So this
Speaker 4: is a sad condition to look at. But this one,
Speaker 4: it says the hallmark sign is called poikiloderma. And this
Speaker 4: is I think we talked about this briefly with other
Speaker 4: conditions on the skin thing that we did. If I'm
Speaker 4: not mistaken, I can't remember what does it cause it's
Speaker 4: it's called poikoloderma and it's a it starts as redness
Speaker 4: or blistering or rash then develops into patches of model pigmentation,
Speaker 4: thinning skin, and visible blood vessels. I think we talked
Speaker 4: about it with the butterfly babies.
Speaker 1: This is I think this is the picture here.
Speaker 4: Yeah, and so this guy obviously starting with the facial
Speaker 4: rash and all of that kind of stuff. It says
Speaker 4: the rash often begins on the face and then it spreads.
Speaker 4: It can spread to the rest of the body. They
Speaker 4: have sparse or absent hair, eyelashes, and eyebrows, so alopecia
Speaker 4: for these people. Hair loss. That is like if if
Speaker 4: this person came into a normal office, they would immediately say,
Speaker 4: this is just tivees.
Speaker 1: Or Stevens Johnson syndrome.
Speaker 4: Yes, I'm kind of virus. You know, it's got to
Speaker 4: work its way through your system. This is going to
Speaker 4: be another one where they're good.
Speaker 1: Especially with these circulars. A lot of times it starts
Speaker 1: with these and that's so indicative of Stevens Johnson syndrome,
Speaker 1: which is caused by.
Speaker 3: An allergy to a medication, usually an antibiotic. And I
Speaker 3: actually had that, which I never had before. After my surgery,
Speaker 3: I all of a sudden became allergic to something, and
Speaker 3: so it was weird. I'd never had that before, but anyway,
Speaker 3: I knew that I got diagnosed and with these circular dots.
Speaker 3: So if he came in like that and then it
Speaker 3: eventually spread out like I'm assuming it did, they would
Speaker 3: definitely misdiagnose this.
Speaker 4: One hundred person. And this what we're looking at right
Speaker 4: now is a picture of a boy's back, and he
Speaker 4: has a lot of them are circular. There's one that
Speaker 4: actually looks like a ginger root like the bone, yeah,
Speaker 4: you know, and and some of them are kind of
Speaker 4: like shape like you would see amibas under a microscope.
Speaker 4: But this and then since it wraps around the sides,
Speaker 4: it wouldn't shock me if there wasn't a doctor that
Speaker 4: looked at this and was like, oh, well, you have shingles.
Speaker 3: Our gluten allergy or some crazy little thing. And then
Speaker 3: it's not the thing.
Speaker 1: So so.
Speaker 4: Along with you know that the skin and the hair
Speaker 4: issues that they have, of course they're they're also short again,
Speaker 4: and then they have skeletal abnormality, so they have uh,
Speaker 4: absent or malformed thumbs and forearms, which is very common
Speaker 4: in them, abnormal bones in the arm's legs, or ribs,
Speaker 4: and so because this one affects mostly their ability to
Speaker 4: repair DNA and stuff that comes from like collagen production
Speaker 4: and things like that, that's why that happens. They also
Speaker 4: are very prone to osteoporosis as babies, which that's crazy,
Speaker 4: but again they're not uptaking vitamin D like they're supposed
Speaker 4: to do. They also get cataracts in their eyes very easily.
Speaker 4: Dental abnormalities again so either really small or missing teeth.
Speaker 4: They're you know, like their teeth don't grow in properly
Speaker 4: or they're drag jagged, misshaped. They're also very sensitive photosensitive
Speaker 4: to light. And of course again the premature aging, and
Speaker 4: it says this one has an extremely high cancer risk rate.
Speaker 4: And so because it has to do with collagen and
Speaker 4: things like that, osteosarcoma, which is bone cancer is the
Speaker 4: most common thing. Also get skin cancers because they get
Speaker 4: the rashes and the pigmentation problems and things of that nature.
Speaker 4: And it says life span for these kids depends on
Speaker 4: the severity and the cancer risk that they have and
Speaker 4: how they you know, take care of that. But they
Speaker 4: also have very frail, sun damaged skin, and so it's
Speaker 4: like elderly skin where I said, it gets like almost
Speaker 4: translucent see through.
Speaker 3: And as soon as your skin opens, and isn't your
Speaker 3: line of defense anymore? Right, you get everything, You get
Speaker 3: so many diseases. And this kid again shows it on
Speaker 3: the face really well. I think it shows that mapping.
Speaker 4: And and he this little boy, because he has a
Speaker 4: rash like all over his cheeks. It wouldn't shock me
Speaker 4: if he came in with us and they were like,
Speaker 4: oh rosiola m em. So of course, you know, like
Speaker 4: protecting your skin from the sun. Orthopedic care since your
Speaker 4: bones are involved, and so they may have to do
Speaker 4: surgeries for you know, uh, straighten your bones or you know,
Speaker 4: break them and re reform them whatever. Uh, lots of
Speaker 4: eye surgery for the cataracts and glaucoma issues and things
Speaker 4: like that, and of course watching for cancer veillance, surveillance.
Speaker 4: So these conditions, these three that we've talked about so
Speaker 4: far in the sideshow, they were either marketed as old
Speaker 4: children or Methuselah children.
Speaker 1: Oh wow, that was their boy.
Speaker 4: Uh, you know, fabulous claimed to fame right, so probably.
Speaker 1: Didn't last long. That's why we couldn't find the pictures
Speaker 1: so much.
Speaker 4: Yeah, no, and that's why it said, like, uh, even
Speaker 4: though there were performers in the side shows that had
Speaker 4: these conditions, they didn't know at the time what these
Speaker 4: conditions were called, or they had such a short life
Speaker 4: expectancy that per former names weren't listed, but they were
Speaker 4: on the bills as like children that never or people
Speaker 4: that never age, or Benjamin Button syndrome was even though
Speaker 4: that's completely backward of what progeria is, so.
Speaker 1: Right, wild.
Speaker 4: So the next thing is Werner syndrome, and that means
Speaker 4: adult progeria again genetically inclined, and says that they develop
Speaker 4: rapid aging, usually in young adulthood.
Speaker 3: Wouldn't that be wild to just be like I got
Speaker 3: married to this guy and he was totally normal, like
Speaker 3: back in the day when people didn't know, and then
Speaker 3: he looked like an old man all of a sudden
Speaker 3: in his thirties.
Speaker 1: Oh my gosh. I mean, I wouldn't leave her anything,
Speaker 1: but she's Louise. It would be a shock.
Speaker 4: Yeah, exactly, you wake up one morning and like, I
Speaker 4: have a full head of gray.
Speaker 1: Hair, and right, yeah, what happened.
Speaker 4: So it says with this condition, especially since it develops
Speaker 4: later in life when they're young, adults are into adulthood,
Speaker 4: they get gray hair really quickly, develop cataracts, skin changes,
Speaker 4: and it says that of course this is another one
Speaker 4: with premature aging BOK, but this one also has to
Speaker 4: do with DNA repair and stuff like that. It's just
Speaker 4: they classify these as different syndromes because of like age.
Speaker 3: And I'd liked this graphic to show like the differences
Speaker 3: in the two because I thought they did this really well.
Speaker 3: So I put this in here because I thought, oh,
Speaker 3: that's a nice way to separate it out and show
Speaker 3: you guys, like what is the difference because it's similar,
Speaker 3: It's really similar, but it's not the same thing.
Speaker 1: And so this is also I thought this one was helpful.
Speaker 3: I don't know why they don't have these little diagrams
Speaker 3: for everything, but they don't, but this one was great.
Speaker 1: I wish they had more of these.
Speaker 4: YEP, I think that is perfect. And so because this
Speaker 4: usually lays dormant until late adolescents early adulthood, it says
Speaker 4: symptoms usually occur like in their twenties or after, so
Speaker 4: they have growth problems, they have a lack of pupidal
Speaker 4: growth spurts, and so they usually have short stature premature
Speaker 4: graying or hair loss, so they can go bald as well.
Speaker 1: Skins forty four, you guys.
Speaker 4: Yeah, and she literally does not look forty four. The
Speaker 4: woman that we're looking at has blonde hair, but because
Speaker 4: of her features from this to me, she looks like
Speaker 4: she's maybe like fifty eight.
Speaker 1: Yeah, yeah, at least ye. Yeah.
Speaker 4: And so their skin becomes thin, tight and a trophy
Speaker 4: that looks really aged.
Speaker 3: This is my favorite picture, this girl as a teenager
Speaker 3: and then by age forty eight.
Speaker 4: Wow, my house, she's changed. So the side by side
Speaker 4: picture that we're looking at right now, and of course
Speaker 4: she has this wer nurse. And from going from what
Speaker 4: she looked as a beautiful she was a really pretty
Speaker 4: girl to the picture on the on the right where
Speaker 4: she is older, she looks like ninety. Yeah. She like
Speaker 4: aged like seriously rapidly. So this says that they get
Speaker 4: of course, cataracts and both eyes at the same time,
Speaker 4: their voice gets really hoarse, they get the wrinkles, and
Speaker 4: then they have underdeveloped sexual characteristics, including in fertility.
Speaker 3: This one I kind of think it's odd too. I've
Speaker 3: never met anybody with this syndrome. But both of them
Speaker 3: are very nice looking. I don't know if that's just
Speaker 3: like an accident like whatever, But I wonder if like
Speaker 3: it's a really good to really bad that's I just
Speaker 3: am not sure and I don't know.
Speaker 4: We talked about the woman. There's a side by side
Speaker 4: underneath it of a man and you know what he
Speaker 4: looked like, as you know, was he supposed to be fifteen.
Speaker 1: To twenty yeah, like twenty fifteen.
Speaker 4: And then what he looks like, you know, just a
Speaker 4: short slider and it literally looks like uh maybe yeah, yeah,
Speaker 4: the agent is crazy.
Speaker 3: I mean, it would just be such a shock because
Speaker 3: back in the day they just didn't have enough diagnosing
Speaker 3: and and I just can't imagine all of a sudden,
Speaker 3: right like.
Speaker 4: That person, That would be shocking. Yeah. Now if you
Speaker 4: if you had a baby that was born that way,
Speaker 4: you kind of like get used to it and you're
Speaker 4: thinking maybe maybe they'll grow out of it, maybe something
Speaker 4: will change or whatever. But like you said before, if
Speaker 4: you're with somebody and they like change, oh right, but
Speaker 4: like verneractively or like what.
Speaker 2: In the world, like yeah, and then you'd be terrified
Speaker 2: to lose them, Like I mean, can you imagine all
Speaker 2: of a sudden now you expect to be with somebody
Speaker 2: till they're like old, you know.
Speaker 1: And I know people lose their other halves all.
Speaker 3: The time through other reasons, but it would just be
Speaker 3: that daunting, right, it would be there every day instead
Speaker 3: of that, Yeah, people died car rex and that's just
Speaker 3: over you know or whatever, but this would be every
Speaker 3: day well, and.
Speaker 4: This would this would be very scary because since they
Speaker 4: you know, contracted in their early or later adolescents, early
Speaker 4: adulthood or whatever, of course, they're prone to arteriosclerosis, heart
Speaker 4: and heack stroke, Diabetes is really common in them, osteoporosis
Speaker 4: because it affects the bones.
Speaker 3: You can tell she has that. You can see in
Speaker 3: her clapicals that it's already.
Speaker 4: Right, and that's you know. They're also at the increased
Speaker 4: cancer risk because of you know, the DNA repair factors.
Speaker 4: So thyroid cancer, melanomas, and sarcomas are common. And also
Speaker 4: leg older leg ulcers is a very common thing in
Speaker 4: these older progeriaations. So the their lifespan is usually only
Speaker 4: forty to fifty years and that's it because they have
Speaker 4: all these complications for it. Wow, so I don't know,
Speaker 4: kind of crazy, yeah, side sid again, no cure but
Speaker 4: we're working on experimental approaches to see if we can
Speaker 4: use any of you as lab rats for gene therapy
Speaker 4: or crisper technology or drugs.
Speaker 1: Thank you.
Speaker 4: Hard pass. So the next one and is the only
Speaker 4: patient that I have ever, ever ever seen in all
Speaker 4: of my ears on this planet with one of these
Speaker 4: premature aging or skin changes. And it is called sclroderma,
Speaker 4: So it gives the appearance again of the premature or
Speaker 4: untimely aging. But this one is the only one on
Speaker 4: all of our lists today that is not genetic in nature.
Speaker 4: It's autoimmune. And this one is autoimmune with connective tissue stuff.
Speaker 4: And they have no idea why, but your body attacks
Speaker 4: connective tissue. So what we're looking at right now is
Speaker 4: a person that it's hands and fingers that we're looking at,
Speaker 4: and they're very discolored. They're like the fingertips and down
Speaker 4: to the you know, first knuckle, second knuckle are white,
Speaker 4: but the rest of the hand is like solid purple.
Speaker 1: And they break off. I had it.
Speaker 3: So my aunt's husband had this, and he had really
Speaker 3: bad lupus and then he got this on top of it,
Speaker 3: and oh my gosh, she started losing fingers.
Speaker 1: So that was scary.
Speaker 4: That would be very Hey, honey, could you give me
Speaker 4: I found this?
Speaker 1: Okay, we're smart as well. You guys already know, like right.
Speaker 4: So don't take offense. But if you find my finger
Speaker 4: on the floor, it's not a dog.
Speaker 1: Yeah, throw it away because there's nothing they can do.
Speaker 4: So it it almost looks like like this other guy
Speaker 4: that we're looking at. It shows the palms of the hands. Uh,
Speaker 4: so everything is normal except for uh the second and
Speaker 4: third finger the right hand and the index finger on
Speaker 4: the left hand are super white, like there's no.
Speaker 1: Color, like what when you burn off all your skin
Speaker 1: white like.
Speaker 4: That, Like he's albino down to the first knuckle.
Speaker 1: That's right, and then they're immobile from it, which is
Speaker 1: so sad.
Speaker 4: So imagine like not being able to especially if you
Speaker 4: work with your hands or something and you're not able
Speaker 4: to like bend because your joints stiffened in your fingers
Speaker 4: can fall off and people, that's not a joke. That
Speaker 4: really does happen because it cuts off the blood supply
Speaker 4: and the whole nine yards in your in your fingers.
Speaker 4: So scary, so this one because it causes your skin
Speaker 4: and connective tissue to become tight, thick and hard. It
Speaker 4: can affect not just your skin, but multiple organs because
Speaker 4: of the connective tissue involved. So you know with the
Speaker 4: skin changes and stuff, especially on the face of the hands,
Speaker 4: loss of normal skin folds. And if you don't know
Speaker 4: what that is, like, look at your hands right like
Speaker 4: I have. I have wrinkly hands. I don't have sclare
Speaker 4: derma or any of the other stuff. I just have
Speaker 4: wrinkly hands. But you you get changes. Your face looks
Speaker 4: mask like. It talks about that a lot where it
Speaker 4: almost looks like, what are those white? I don't I'm
Speaker 4: talking about masks white like porcelain mask or whatever.
Speaker 1: Yep, yep.
Speaker 4: So because your fingers become tapered and stuff which tapered
Speaker 4: means they become thinner like a taper candle.
Speaker 1: Right that pinky shows it perfectly.
Speaker 4: Yes, they get sclerodactyly. So we talked about ectodactyly on
Speaker 4: the Mermaid episode episode the number one that we did
Speaker 4: on this. So this happens, and then they also get
Speaker 4: because of the connective tissue, it affects the vascular system,
Speaker 4: so they get ray nods, which I have seen ray
Speaker 4: nods like multiple times in my life. So your fingers
Speaker 4: are toes turned white blue and then red in response
Speaker 4: to cold or stress. Sometimes discoloration stays like permanently.
Speaker 1: The bluish on her fingers is rain ods here, you guys.
Speaker 4: And then also because it affects the vascular ture of
Speaker 4: the body, you get tele anglictosis, which is it looks
Speaker 4: like a dilated blood vessel, but it's like a kind
Speaker 4: of looks like a spider web. It has the like
Speaker 4: the ball and the metal and then tons of little
Speaker 4: fingers that come out from it. And so you'll see
Speaker 4: those a lot of times on people that have like
Speaker 4: thinner skin. It's generally common to see it on the
Speaker 4: thighs or the ankles. But you can have these inside
Speaker 4: your body as well, and so your veins can start
Speaker 4: spidering like this inside your body, which who can cause
Speaker 4: a whole host of other problems, and it in turn
Speaker 4: goes into the organs. This can affect the lungs, the kidneys,
Speaker 4: the GI tract, or the heart, so they get fibroids
Speaker 4: and the lungs. Pulmonary hypertension is very common, so your
Speaker 4: blood pressure is going to raise because your pulmonary vessels
Speaker 4: aren't releasing the pressure like they're supposed to. But the kidneys,
Speaker 4: people often go into a renal crosss and so you
Speaker 4: can die from that because you can't excrete the toxins
Speaker 4: and things like that from the body. Common to have
Speaker 4: reflux which will also erodure esophagus after time, malabsorption so
Speaker 4: they can't absorb vitamins, nutrients, minerals, things like that. And
Speaker 4: the heart, it's really common to have arrhythmias and cardiomyopathy
Speaker 4: because with the formation of all these spider type things,
Speaker 4: it causes the blood in your heart not to pump properly,
Speaker 4: and so it causes a build up or a backup
Speaker 4: of blood and as all calling up.
Speaker 1: Terrible.
Speaker 4: So this can be localized, which means that its only
Speaker 4: skin or the systemic type, which like I said, can
Speaker 4: can go everywhere, and even your esophagus can stop moving
Speaker 4: with this. And because that's a problem, and it also
Speaker 4: affects your gi tract, your bowels like and the motility
Speaker 4: and your bowels and your ability to poop right and
Speaker 4: to because we have what's called peristalsis, which is the
Speaker 4: squeezing motion in your any kind of muscle in your body.
Speaker 1: And so let me get the poop back.
Speaker 4: That kinda Yeah, it kind of gets deadened and so
Speaker 4: that you're not able to excrete what you need to.
Speaker 4: And so is it common for people with us to
Speaker 4: end up with that?
Speaker 1: Sure? Of course, right makes sense.
Speaker 4: So this is the only person I've ever seen, Like
Speaker 4: I said, I had a patient and her skin was
Speaker 4: so hard, Like going to try to get a blood drill,
Speaker 4: it got like uber thick and was like trying to
Speaker 4: stick the tiniest needle.
Speaker 1: The dummy, like the dummy at class, Like.
Speaker 4: It's like trying to stick a needle into a very thick,
Speaker 4: very hard rubber sole of a shoe. It was so
Speaker 4: hard to get blood from her, and it was like
Speaker 4: hardened and weird like, but her like skin everything she
Speaker 4: was it was very wrinkly and discolored and all of
Speaker 4: that stuff. So yep, So this is prognosis wise depends
Speaker 4: on the type, whether it's localized or whether it's systemic
Speaker 4: organ related, and what kind of proactive things that you
Speaker 4: do to help this along. Because it is autoimmune, they
Speaker 4: say there's no cure. There's always something you can do
Speaker 4: for autoimmune. But anyway, they say take immunosuppressants, or they
Speaker 4: could do vasodilators for the raynods, the bluing or purpling
Speaker 4: in the hands, proton pump inhibitors for any kind of
Speaker 4: reflex or esophageal thing. But you may end up having
Speaker 4: to have especially and this is not just for these patients,
Speaker 4: but any patient has chronic reflux. What it does over
Speaker 4: time is eroad the mucosal lining in your esophagus and
Speaker 4: then it starts to build up what we call webbing,
Speaker 4: so kind of like spider webbing or whatever, which prevents
Speaker 4: you from being able to swallow properly. And they actually
Speaker 4: have to go in and dilate your esophagus to be
Speaker 4: able to get things to move up and down. So
Speaker 4: people that have chronic reflux and stuff, a lot of
Speaker 4: times food gets stuck. We've have patients where like steak
Speaker 4: or you know, a piece of meat if some kind
Speaker 4: got stuck and they had to go in and actually surgically.
Speaker 1: Yeah, my grandpa had to have is dilated like four times. Yeah, yeah,
Speaker 1: I think he had a little bit of Marfan syndrome.
Speaker 3: And anyway, it just kept happening and happening, and what
Speaker 3: you're talking about where they had to.
Speaker 1: Go in after it and it was sad. It was
Speaker 1: just yeah, I'm glad they have things like that.
Speaker 4: But a hundred yeah. And so they've also of course
Speaker 4: they're gonna tell them physical therapy. But if your fingers could.
Speaker 1: I don't know.
Speaker 4: I don't know that be very beneficial.
Speaker 3: I don't not with the way they dally out pain
Speaker 3: medicine anymore. Man, I'm like, uh, y'all, don't give people
Speaker 3: anything anymore, And you're gonna tell him take some time
Speaker 3: at all and live through almost losing your hand, I
Speaker 3: don't know if i'd.
Speaker 4: Got So they do have new biological medicines that you know,
Speaker 4: come up that they can treat with or whatever.
Speaker 1: Would you do it? Would you do a biological Yeah?
Speaker 4: No, because these are currently still understudy. So would I
Speaker 4: be a guinea pig knowing what I know now about pharma?
Speaker 4: Hail to the know.
Speaker 3: Just the biologics are so sketchy because we just don't
Speaker 3: know the future for it, right, Like even if they
Speaker 3: say they know, they don't know they.
Speaker 4: Have one hundred percent. And if you're giving somebody a
Speaker 4: biologic kind of like during the colored stuff again, when
Speaker 4: they're giving like monoclonal antibodies and they're saying like uh,
Speaker 4: if you get vaccinated, like it won't shed and then
Speaker 4: we find out that, yes, there is shedding that comes
Speaker 4: from the vacs. So what happens with monoclonal antibodies. They
Speaker 4: aren't studied well enough to know if you can transfer
Speaker 4: anything like that to other people through.
Speaker 3: I think those were safer and like some of the
Speaker 3: things we saw because they pulled it so fast, like
Speaker 3: it must have really been good.
Speaker 1: For you or something. Because one day they were like
Speaker 1: everywhere like these.
Speaker 4: Clinics and we don't have anymore. Sorry.
Speaker 1: I was like, what, this seems weird.
Speaker 3: And I don't know what happened with that, but I
Speaker 3: found it fascinating, right, But then you know, then I
Speaker 3: think it what it was is in my personal opinion,
Speaker 3: then people weren't taking the gbg ab and so yeah.
Speaker 4: One hundred percent, and that's why they immediately it disappeared,
Speaker 4: disappeared by bye ye like overnight it disappeared. So those
Speaker 4: are the things that they are working on for it.
Speaker 4: But when they were these people were in a sideshow.
Speaker 4: They were billed as the mummies or living statues because
Speaker 4: they do tend to be like start to freeze, dried out, stiff,
Speaker 4: and aged and so, like I said, lady, I had
Speaker 4: good luck to anybody that's not a skilled at the
Speaker 4: botomy or anything trying to get get So the next one,
Speaker 4: this is uber interesting. This one is metatrophic dysplasia. And
Speaker 4: it's a rare skeletal dysplasia, which means disorder of bone
Speaker 4: and cartilage growth. Also can give the person like unusual
Speaker 4: body proportions, also premature to give you well, yes, and that.
Speaker 1: I don't know how else to describe it.
Speaker 4: Man, it is we're looking at a butt a baby.
Speaker 4: But and so this baby definitely as like the sacrum
Speaker 4: grew into a tail, and so it is pretty a
Speaker 4: pretty prominent tail.
Speaker 1: It has another tail.
Speaker 4: The other picture that we're looking at now, it is
Speaker 4: definitely sorry there it goes very disproportionate size boeing of
Speaker 4: the legs, disproportion of the joints, like really extra large knees,
Speaker 4: or the arms are disproportionately shit.
Speaker 3: I have to give it to the kid in picture
Speaker 3: A though, he's like trying to be ripped like, which
Speaker 3: is good.
Speaker 4: But notice like the limb difference in his arms. Oh yeah, almost. Well,
Speaker 4: the last picture you can't really tell so much. But
Speaker 4: the first two. There's definitely a limb difference where it looks.
Speaker 2: I think this might be the same kids difference.
Speaker 3: Uh huh, look at this arm. I think this is
Speaker 3: the same kid grown up. Maybe because look at the
Speaker 3: arm length difference. I don't know, but anyway, Yeah, it's weird.
Speaker 1: Yeah, so this is.
Speaker 4: An interesting one because this is another genetic one. But
Speaker 4: this is a skeletal disorder. So we could have also
Speaker 4: talked about this and the last you know, skeleton thing
Speaker 4: we did. But this is a mutation of a gene
Speaker 4: that helps to regulate calcium flow for cartilage and bone cells.
Speaker 4: And so they say that like they named it this
Speaker 4: because metatrophic comes from the Greek world mean changing shape.
Speaker 4: So these kids are literally shape shifters by the meaning
Speaker 4: of the word right, and body proportions change as the
Speaker 4: child grows, and so like the little kid in in
Speaker 4: D he has a little bit of a difference, but
Speaker 4: it's not as pronounced as the patient in a is
Speaker 4: where you can tell that one arm continue growing in
Speaker 4: the other one did not, or even the legs.
Speaker 1: Severe.
Speaker 4: Yeah, so this says, uh, usually occurs at birth. They
Speaker 4: have a normal sized trunk and short limbs. Uh, they
Speaker 4: will get a large head with a prominent forehead. As
Speaker 4: the child grows, uh, the trunk growth slows and so
Speaker 4: then they get like a very short torso and compared
Speaker 4: in comparison to like extra long limbs.
Speaker 1: Are they are they taller? Are they midget type? Are they?
Speaker 4: No, They're they're smaller because the way that the legs
Speaker 4: and stuff like that grows, the arm bones will grow,
Speaker 4: but the legs generally tend to be shorter. Okay, this
Speaker 4: says they're very likely to have spinal curvatures like we
Speaker 4: talked about on the last show, typhosis, scoliosis and lore
Speaker 4: dosis of the spine. So their chest gets an arrow
Speaker 4: and their ribs get really stiff. I can only imagine
Speaker 4: the amount of chest pain that these kids would have
Speaker 4: because a lot of times you'll get what's called kostrochondritis
Speaker 4: and an inflammation of the cartilage that holds your ribs
Speaker 4: to your rib cage, and it feels like a heart attack.
Speaker 4: It can memo heart attack symptoms or like stroke symptoms
Speaker 4: because you'll have the pain that shoots up your neck.
Speaker 4: So with these kids, since their bones are no longer
Speaker 4: pliable and they become stuff, I can't imagine the amount
Speaker 4: of chest pain that these kids would have because of
Speaker 4: the pole.
Speaker 1: Look at how much pressure. Look at this diagram right here,
Speaker 1: everybody this is in a neoy even look at the
Speaker 1: amount of pressure from the below to this rip cage.
Speaker 1: That's small.
Speaker 4: Yeah, because the all the what we're looking at as
Speaker 4: a like an X ray of the baby next to
Speaker 4: the actual image of the baby. The upper chest is
Speaker 4: very very tiny, it's tapered, it's very narrow, and all
Speaker 4: of the organs are pushed down into the abdomen. The
Speaker 4: abdomen is very misshaped and very bloated. And that's what
Speaker 4: happens because since you don't have that cartilage in the
Speaker 4: ribs to let them expand and contract. Even breathing is
Speaker 4: difficult because your lungs have to expand. Your heart expands
Speaker 4: when it pumps, so it's literally shoved every organ down
Speaker 4: into the abdominal cavity.
Speaker 1: Oh scy and as that liver grows, the amount of
Speaker 1: size that's gonna get is going to be rough one
Speaker 1: hundred percent.
Speaker 4: So the hips get very abnormal. Because you have cartilage
Speaker 4: also in your hip joints that allows expanding and contracting,
Speaker 4: especially for females, if you regret to that age with
Speaker 4: one of these kids, but that hardens and stiffens as well,
Speaker 4: so you you not only have the bowd legs, but
Speaker 4: it becomes stiff and your joints are stuff.
Speaker 3: This kid is one on a that has the cayphosis
Speaker 3: like she was talking about. But you can literally see
Speaker 3: the pulling of his rib cage like inward to the scapula.
Speaker 3: It looks right, very painful.
Speaker 4: It is like pulled over to one side. And so
Speaker 4: this kid, because of the curvature of the spine, it
Speaker 4: looks like his organs have shifted to the right side
Speaker 4: of the body.
Speaker 3: So painful looking. And he does have a weird tail. Also,
Speaker 3: it's strange, I don't.
Speaker 4: Know, and very abnormal legs. Look at the right knee
Speaker 4: on this kid, it's like the it's like the knee
Speaker 4: joint fuse to the bone or something instead of being
Speaker 4: free floating. Yeah, And so with that, they also get
Speaker 4: the age look because they have a small chin, very
Speaker 4: prominent eyes. They've said that the eyes kind of like
Speaker 4: stick out as the facial feature to look at, and
Speaker 4: wrinkling from tight skin over the bone and so loss
Speaker 4: of col relig and stuff like that. Some of these
Speaker 4: people look like skin hanging over bone because there's nothing
Speaker 4: underneath of it, like we normally have a fatty layer
Speaker 4: and stuff, but that doesn't happen. And a lot of
Speaker 4: these kits, so it says they're often always very short
Speaker 4: in stature, less than four foot tall. No, I am
Speaker 4: not one of these patients. I am four foot so
Speaker 4: I don't qualify.
Speaker 1: Sorry, yeah, it's bigger than that. She's taller, I am.
Speaker 1: I have a whole foot not very much, yes, but
Speaker 1: to them.
Speaker 4: Exactly so, because of the hardening of the bones and
Speaker 4: stuff like that, and the stiffening of the connective tissues
Speaker 4: and whatever we talked about their organs moving and shifting
Speaker 4: things like that. Obviously respiratory issues because they can't inflate
Speaker 4: their lungs because there's no room for the alveoli, which
Speaker 4: are like the balloons in your lungs. There's no place
Speaker 4: for them to like expand and get bigger. Joint stiffness
Speaker 4: and arthritis is a problem. Spinal cord compression because it
Speaker 4: hardens because the disk in your back get compressed because
Speaker 4: you know, all of that dries up as well, so
Speaker 4: you'll have spinal cord issues and compression progressive disability with age,
Speaker 4: so the older they get, the worse they get. Like
Speaker 4: life expectancy depends on severity. But the lethal form causes
Speaker 4: death and infancy, but the non lethal they may be
Speaker 4: able to if they're lucky survive into early adulthood. Wow,
Speaker 4: so not great, not great at all.
Speaker 3: I would think that these guys they could fix. I know,
Speaker 3: but if you weren't gonna live very long, if I
Speaker 3: wouldn't do it.
Speaker 1: If you weren't gonna live very long. Yeah, but they
Speaker 1: can make you taller.
Speaker 3: In Asia, people are like freaking chopping their knees open
Speaker 3: and making themselves taller and crazy stuff.
Speaker 1: So you would think they would be able to fix
Speaker 1: a lot of these deformities, at least in the bone
Speaker 1: structures and stuff.
Speaker 4: Well, I me, I don't know if I would want
Speaker 4: to have anything done if I had this, even if
Speaker 4: I had like the bony abnormalities and stuff like that,
Speaker 4: because since everything is so like stiffened and hardened, I
Speaker 4: can't imagine the amount of pains that they would have,
Speaker 4: like if they went in did reconstructive surgery or put
Speaker 4: like external fixation, which means like putting rods and stuff
Speaker 4: like that. From the outside of the body through the
Speaker 4: bone to you know whatever, stuff like that. I can't
Speaker 4: imagine how that would go. And if this is progressive
Speaker 4: and it gets progressively harder, the bone gets stiffer with age, Like,
Speaker 4: how would she be able to get any hardware out
Speaker 4: of your body? I would think it would grow over
Speaker 4: it rapidly.
Speaker 1: I hope this isn't her tail.
Speaker 4: She does. Okay, we're looking at a picture.
Speaker 1: I'm just I don't know what's happening here.
Speaker 4: This girl is in a nightgown and it literally looks
Speaker 4: like a weyous something's going on. So either it is
Speaker 4: a tail or, it is a drape flap in the front.
Speaker 4: Not sure.
Speaker 1: I really hope it's a wardrobe error. I don't know
Speaker 1: what's happened there, but I had to say something.
Speaker 4: I'm glad we can point these things out, especially for
Speaker 4: the people who are not watching.
Speaker 1: There you go.
Speaker 4: So these patients were billed as little old men or
Speaker 4: ancient children.
Speaker 1: I don't know why.
Speaker 4: No cure, but lots of orthopedic surgery for scoliosis or
Speaker 4: joint problems if you want to go through that, physical
Speaker 4: therapy for mobility.
Speaker 1: But how much I would have I would have my
Speaker 1: tail removed.
Speaker 4: I'm sorry you would would you save it in a jar?
Speaker 1: Oh? I don't know, but I wouldn't want that big one.
Speaker 4: Hey that looks like does your tail hang low? Does
Speaker 4: it work? Can you te to bow?
Speaker 3: I mean this kid can't, but that first kid could.
Speaker 3: The girl that first kids tell man? I was like,
Speaker 3: what is doing on here? This is Oh boy, that's
Speaker 3: a lot.
Speaker 4: That would be awful And I can't imagine like trying
Speaker 4: to clean around that because like they're such deep uh
Speaker 4: clere crevices.
Speaker 1: Yep, very weird.
Speaker 4: Yeah, I don't know, but would you outside of doing
Speaker 4: your tail, would you do anything else?
Speaker 1: Depends on if I was going to live right, like
Speaker 1: and if I if it would help my mobility, if
Speaker 1: it like do you give up pain for mobility? Maybe so?
Speaker 1: Maybe so?
Speaker 4: But even like when they say, uh, physical therapy.
Speaker 1: Like how I don't know if I would?
Speaker 4: Now was physical therapy going to help you if you
Speaker 4: have no ability to.
Speaker 3: We all know that that's just a lie now because
Speaker 3: they don't want to give pain meds because the world changed.
Speaker 3: And I understand that there is addiction and problems in NASCO,
Speaker 3: but there's also real pain, and so we have to
Speaker 3: pull our heads out of our asses and start treating
Speaker 3: the people that have these problems, that have real pain
Speaker 3: versus you know, the other situation. And I'm sorry, if
Speaker 3: they're gonna die at twenty, who cares if they're an addict?
Speaker 3: Not really, I don't really care. Like, let them be
Speaker 3: pain free and live a normal life. Yeah, I'll get
Speaker 3: this on the road.
Speaker 4: I can't imagine people with this having a normal job,
Speaker 4: holding down a normal job, like if they had to go,
Speaker 4: like to a corporate job or something. Maybe if you
Speaker 4: work from home where you could like be you know,
Speaker 4: relaxed and whatever in your own surroundings, But I can't
Speaker 4: imagine having to go somewhere to work.
Speaker 3: No, I think this is probably a permanent disability, is
Speaker 3: my guess.
Speaker 1: Although the one kid looked very functional, so.
Speaker 4: This one of course, uh, respiratory stuff because they can't
Speaker 4: expand their lungs. But again, even an inhaler that's not
Speaker 4: going to do anything. If you're if your ribs or
Speaker 4: are squishing together and you can't inflate your lungs, how
Speaker 4: is a inhaler or sperometery gonna help. It's not because
Speaker 4: you can't inhale deeply enough, and it says genetic counseling
Speaker 4: for the families.
Speaker 1: So don't make any more kids, basically, I mean pretty much.
Speaker 1: I guess.
Speaker 3: I guess if you're only going to live till you're twenty,
Speaker 3: probably not too responsible to pop out a bunch of kids.
Speaker 1: So I don't know, that's up to the couple.
Speaker 4: Though, Yeah, who knows, who knows what they're going to
Speaker 4: do with this. So the next one is zero derma
Speaker 4: pigmentosum and it's also got the untimely aging and stuff.
Speaker 4: Also respond full for DNA repair, but this one, again
Speaker 4: being genetic, this has to do with nucleotide excision repair,
Speaker 4: the system cells normally use to repair dnate damage from
Speaker 4: ultraviolet light. Again, some more skin conditions, and it says
Speaker 4: because damage isn't repaired, mutations actually will accumulate in your skin,
Speaker 4: leading to premature aging or very high rates of skin cancer.
Speaker 3: And so I would say that's some premature aging on
Speaker 3: the bottom.
Speaker 4: That okay. So it's a collage of four pictures. So
Speaker 4: the first one, the little girl, she's got a little
Speaker 4: bit of pigmentation discoloration because of some damage. The second
Speaker 4: one it literally looks like the girl like her entire
Speaker 4: face is full of freckles or age spots. The third one,
Speaker 4: this is where we start crapy because this no longer
Speaker 4: looks like age spots or or freckles or anything. It
Speaker 4: looks like the skin is starting to like blister or something.
Speaker 4: It's on the tip of her nose, it's all over
Speaker 4: above her eyebrows, all her cheeks, and her eyes are
Speaker 4: starting to look like blistered or damaged. And then in
Speaker 4: the last picture, the woman has no eyeballs. Yeah, that's
Speaker 4: there gone.
Speaker 3: You would think she would have learned to stay out
Speaker 3: of the sun a that would have been my first
Speaker 3: plan of attack.
Speaker 4: Or if they know about photosensitivity and stuff, because I
Speaker 4: don't know how old that woman is, but uh, if
Speaker 4: she's like around the age of my parents, which is old,
Speaker 4: Uh they don't.
Speaker 1: That was that top picture, That little girl looks like
Speaker 1: a nineties kid kind of you know what I mean.
Speaker 1: It doesn't look like I don't know, but uh, it's definitely.
Speaker 4: Yeah. The two on the bottom, it literally looks like
Speaker 4: because all of this sun damage and stuff started to accumulate,
Speaker 4: it literally looks like it's eating her face off.
Speaker 1: Yeah, she looks like like and I think they did
Speaker 1: build them even as vampires or moon children because they
Speaker 1: couldn't go outside at the daytime.
Speaker 4: So this so this is, oh that that last picture
Speaker 4: that is some great stuff where it's like, yeah, there's
Speaker 4: there are no This one is creepy too, And I
Speaker 4: say creepy even though I've seen a lot of things
Speaker 4: in my lifetime, Like this child's eyeballs are almost like zombified.
Speaker 1: It's very overgrown cataract and then very like all skin
Speaker 1: eating where he's pigmented dark, and then it's why it
Speaker 1: just looks really scary.
Speaker 4: Yeah, So it says that this happens in early childhood,
Speaker 4: usually before the age of two. Extreme sunsensitivity, so they
Speaker 4: get very severe sunburns after just very minimal exposure. Starts
Speaker 4: out as freckles, then goes to blistering, then goes into
Speaker 4: pigment changes. And so that's like we were talking about
Speaker 4: with the progression of the pictures, like how it has changed.
Speaker 4: So it causes wrinkling, leathery skin, loss of elasticity, dry
Speaker 4: thick skin with old age appearance. They have photophobia, so
Speaker 4: light sensitivity, conjunctivitis which is infections in the eyeballs, carotitis,
Speaker 4: and cataracts are common. And then because you not only
Speaker 4: take sun or vitamin D and through your skin, but
Speaker 4: also light is absorbed through your eyeballs, they get that's
Speaker 4: where they get the eye problems from, but also neurological
Speaker 4: problems of certain things. They developmental dislay, delays, hearing loss,
Speaker 4: poor coordination, and microcephala. Again because of the vitamin D processing,
Speaker 4: they can't process that, and your eyeballs can't process the
Speaker 4: light rays it's taking in.
Speaker 3: Either that girl seem like she lived quite a while too,
Speaker 3: like she looked, unless she just looks adult like what
Speaker 3: we're talking about.
Speaker 4: But yeah, so these are extremely high risk of cancers
Speaker 4: and they can get all kinds basal cells squamos cel
Speaker 4: or melanomas occurs in early childhood or adolescents. And then
Speaker 4: of course they're telling you use sun protection. Of course,
Speaker 4: no cure.
Speaker 1: Uh.
Speaker 4: It says they need to have full avoidance of UV light,
Speaker 4: including indoor geesh and they need specialty windows and UV
Speaker 4: blocking clothing. So how would you do that indoors?
Speaker 1: It would be rough because you know the government or
Speaker 1: whoever is not going to help you pay for all that.
Speaker 4: Yeah, that would be so expensive. But I mean, think
Speaker 4: about it, like there's literally light from how many sources
Speaker 4: in your house.
Speaker 3: You have to you'd have to tinfoil, like a whole
Speaker 3: basement or something, probably.
Speaker 4: And the only thing that you could use would be
Speaker 4: like candle light.
Speaker 1: Mm hmm yep.
Speaker 4: So that's wild, that's great, And maybe that's why that
Speaker 4: lady's eyeballs are missing.
Speaker 1: Oooh, you know what I mean, that's the thing that
Speaker 1: I would want fixed the most.
Speaker 3: Like, I mean, I get like I am vain enough
Speaker 3: to say I would miss my looks, but I would
Speaker 3: want my eyes.
Speaker 4: I yeah, even even like the fake eyeballs.
Speaker 1: Yeah something, I mean, yeah, you would just hope you
Speaker 1: could at least have your eyes, you know.
Speaker 3: I don't know, this seems like there should be more
Speaker 3: for these people by this point. This seems silly to
Speaker 3: not have figured out, like we have all this SPF everything,
Speaker 3: and it just seems like we should have a better,
Speaker 3: Like don't.
Speaker 1: Ever let this kid go outside ever, you know, blah
Speaker 1: blah blah.
Speaker 3: Like I just don't know, like why is there a
Speaker 3: first time or is this before diagnosis? But it says
Speaker 3: they get it as babies, so I don't know, Like
Speaker 3: I sure you would not take the chance and be like,
Speaker 3: you know what, junior, We're going to risk it today.
Speaker 1: You want to get some sun.
Speaker 4: But that's the thing is like when how how did
Speaker 4: how long did it take for people to diagnose the
Speaker 4: right children? And how much UV light exposure indoor or
Speaker 4: outdoor did any of these kids have before anybody realized
Speaker 4: what was going.
Speaker 1: On before shit got real, right, yeah.
Speaker 4: Right before their eyeballs opt out, all out and if
Speaker 4: you're going to eat, yeah. So, so it says some individuals,
Speaker 4: not very many can live into adulthood and that is
Speaker 4: literally if they avoid every single type of UV light.
Speaker 4: But life expectancy for this is very short, generally speaking,
Speaker 4: because of the high rate of cancer that they these
Speaker 4: could good and do what you want with the cancer diagnosis,
Speaker 4: but you know, whatever. Theory. So this next one is
Speaker 4: called cutest laxa uh that that has untimely aging and
Speaker 4: things like that. But this one is mostly a connective
Speaker 4: tissue disorder affecting the skins lacticity. So think what was
Speaker 4: it the Incredibles skin? Yeah, with the super stretchy elastic
Speaker 4: man type whatever, you can pull your skin and wrap
Speaker 4: it around you as a winter.
Speaker 1: No skin folds are unfortunate. These are going to be
Speaker 1: a problem later.
Speaker 4: So this this is super interesting. This is another rare
Speaker 4: genetic thing.
Speaker 1: It's this is a mix. I'm almost positive.
Speaker 4: Yeah. It has has to do with the elastin, which
Speaker 4: is what gives you the elastic mobility of your skin
Speaker 4: to like snap back into the place and connective tissues.
Speaker 4: So it's going to affect a lot of things. So
Speaker 4: this one says can be congenital at birth or acquired
Speaker 4: later in life. So the skin is loose, saggy, wrinkled,
Speaker 4: and giving an aged and elastic appearance. Wrinkles are immature
Speaker 4: even in infants. So baby's born with us. Some of
Speaker 4: the pictures again are we're kind of frightening of this.
Speaker 1: It looks like a massive weight loss patient in a child.
Speaker 4: Yes, anybody that's ever seen somebody that's had like gastric
Speaker 4: bypass surgery done and how their skin literally just wrinkles
Speaker 4: and drew.
Speaker 1: Creeps me out that he's pulling his wings.
Speaker 4: So this guy, I thought they were birthmarks and then
Speaker 4: I realized, oh shit, So so this guy has he
Speaker 4: looks like he has had gastric bypass done even though
Speaker 4: he has not his skin on his chest is sagging
Speaker 4: all the way down to his belly and relly, but
Speaker 4: having over it, you can't see his nipples on the
Speaker 4: first picture. Then in the bottom picture he actually took
Speaker 4: those skinfolds and hold them out like he said, like
Speaker 4: chicken wings, and his nipples chicken tits have slid like
Speaker 4: all the way down too. So this would be like
Speaker 4: a woman who tucks her boobs in her pants when
Speaker 4: she gets older. This guy can tuck his nipples in
Speaker 4: his short snoe.
Speaker 1: I would have this fixed.
Speaker 3: I would not want chicken tits, especially as a man,
Speaker 3: but also chicken tits, yeah yeah it I and the
Speaker 3: kids and faces.
Speaker 1: But when it's kids, it's sad.
Speaker 3: But when it's a grown up holding his chicken tits,
Speaker 3: it's a little bit funny.
Speaker 1: And I don't know.
Speaker 3: How to you know, it is what it is. I'm
Speaker 3: gonna say word thinks sometimes like this one is sad
Speaker 3: to me because he's sad, and he looks sad, and
Speaker 3: you know, in.
Speaker 4: The front we're looking at like a compilation of pictures
Speaker 4: from the same little boy from the front, like sitting down,
Speaker 4: he does not look bad, but his legs are so wrinkled.
Speaker 1: He's got wrinkly.
Speaker 4: But and he's little. He's tiny. This guy is a
Speaker 4: tiny kad and his butt and his thighs and everything
Speaker 4: is is super wrinkly and saggy.
Speaker 3: This face one, the face one is rough. I would
Speaker 3: have my kid's face fixed.
Speaker 4: Yeah, this this one is a sagging of the face
Speaker 4: that we're looking at. And it so like the cheeks
Speaker 4: have dropped below like the chin and the jawline.
Speaker 3: And it's not I wouldn't have my kid's face fixed
Speaker 3: because of me. I would have my kid's face fix
Speaker 3: if they wanted it because of the people are mean,
Speaker 3: that's all.
Speaker 1: Yeah, people are assholes.
Speaker 4: So this this kid looks like they're like every bit
Speaker 4: of fat in their face like just slid down underneath
Speaker 4: their jewling.
Speaker 1: And took everything with like just pulling.
Speaker 4: So it's like very hollow under the eyeballs and around
Speaker 4: the eyeballs, and then it's very like puffish, misshaped underneath
Speaker 4: the chin.
Speaker 3: Oh my gosh, it looks like Drewpy the Dog. And
Speaker 3: I don't mean to be a dick, but that is
Speaker 3: the best.
Speaker 1: Way to describe it. Like jewels, mm hmm, yep.
Speaker 3: The way it looks, Yeah, that's the best way and
Speaker 3: this pery orbital swelling. Man, Like, whoa, what's going on there?
Speaker 3: That is that's got it hurt?
Speaker 4: She's talk about is like excessive swelling right under the
Speaker 4: bottom eyelid on both sides. Because again this kid like
Speaker 4: his faces drooping down, you know, and same thing as
Speaker 4: the previous one where it looks like all the all
Speaker 4: the fat and everything has been pulled down underneath his jawline.
Speaker 4: But he has this very enormous swelling underneath his eyes.
Speaker 1: Yeah, you would think they could help that.
Speaker 3: That seems think of your worst hungover day over times,
Speaker 3: like so many more.
Speaker 1: It's just not Yeah, it's rough. You would think there'd
Speaker 1: be something they could do for these kids other than
Speaker 1: just leaving them like that and battling boob.
Speaker 4: I don't know, we're gonna keep clipping back to that
Speaker 4: battling eddy.
Speaker 1: Ah.
Speaker 3: Okay, this one was really bad and sad because this
Speaker 3: guy did make it to older age and he's got
Speaker 3: another thing obviously going on.
Speaker 1: But he also has the sagging.
Speaker 4: Yeah, and this I don't know how old this person is,
Speaker 4: but he like his whole face is very elongated and
Speaker 4: it looks like again all of the fat and stuff
Speaker 4: like pulled down to underneath his jawline, but his looks
Speaker 4: full like his face doesn'onekly that much, but his body
Speaker 4: is very misshaped. His nipples are in a very strange place.
Speaker 1: His abdoms better than.
Speaker 4: Yeah, yeah this this, this guy's got lots of different
Speaker 4: things going on, because you can definitely tell he's got
Speaker 4: curvature of the spine and even like one shoulder is
Speaker 4: higher than the other one if you look at that
Speaker 4: second picture.
Speaker 3: So he's still showing up in his sexy panties though
Speaker 3: I mean his underwears, right, he does wear those.
Speaker 4: Guys, he does have some the uh what do you
Speaker 4: call those?
Speaker 1: They're underwears.
Speaker 4: He's got like bikini's beetles on.
Speaker 1: Yeah, it just don't right, yeah no, but a he's
Speaker 1: he's showing up for it. He actually looks like a
Speaker 1: super happy guy.
Speaker 4: So the legs look like kid legs mm hmm. But
Speaker 4: the rest of this guy looks old and very deformed.
Speaker 4: So even his face, uh, even his face is like
Speaker 4: slanted and curved, which was abnormal.
Speaker 3: Found this over and over with the people that have this. Like,
Speaker 3: she doesn't have the wrinkles as bad, but they're there,
Speaker 3: but it seems like a multi diagnosis situation often.
Speaker 4: Yeah, I would agree, so and very she's also very
Speaker 4: like abdomen is distended, arms are really long because they're
Speaker 4: literally down to her knees, not the malformation of the feet. Yeah,
Speaker 4: the long hetted face.
Speaker 1: Strange how much it changes.
Speaker 3: And this person literally looks like they have saram wrapped
Speaker 3: themselves because it's so many folds and I'm sure they haven't.
Speaker 1: I'm sure it's a fold cutting the circulation to the
Speaker 1: other fo.
Speaker 4: Yeah, and we're looking at a person's back and like
Speaker 4: how wrinkly and stuff, not just the back is, but
Speaker 4: also the back of the arms.
Speaker 1: Yeah, so yeah, it's weird.
Speaker 3: It's almost like drape draping in a way. And then
Speaker 3: this isn't quite as bad. This is, I mean, sort
Speaker 3: of bad, but hey, seeing the way.
Speaker 1: Worse to me.
Speaker 4: This it's a picture of three different ladies and it
Speaker 4: shows their face and then the shows their neck and.
Speaker 1: There it's her progression as she ages.
Speaker 4: Maybe maybe the first the first picture, like, okay, I
Speaker 4: don't really see anything wrong with that. The second one
Speaker 4: it's getting a little creepy. And the third one, especially
Speaker 4: on the abdomen, it is very drapery skin, yeah.
Speaker 1: And creepy like, yeah, it's gonna tear.
Speaker 4: Something like crape paper yep.
Speaker 1: And then this lady's face.
Speaker 4: Neither one with the dog jawls gewls.
Speaker 1: Yeah.
Speaker 3: I don't know what else you say about that. But
Speaker 3: her ears are also impressive. I don't know if that's
Speaker 3: on purpose or not. I don't know if that's part
Speaker 3: of her disease or if she stretched them, but weird.
Speaker 4: Nevertheless, her ears look like they're down halfway down her
Speaker 4: neck almost her shoulder. So yeah. Interesting. So these people,
Speaker 4: of course the skin things that we talked about and whatever,
Speaker 4: and the lawyer looks like their stuff is sliding off
Speaker 4: of their face or or whatever. But they also are
Speaker 4: going to have respiratory problems, especially emphysima or tracheal collapse
Speaker 4: that would be awful in certain cases depending on the
Speaker 4: type and severity of it. They have cardiovascular problems, heart
Speaker 4: valve abnormalities, aortic dilation, they have musculo skeletal issues like
Speaker 4: we talked about. Hernias are very common in these people.
Speaker 4: And then of course gastro intestinal problems, so they can
Speaker 4: also outside of the hernias, get diverticuli because of the
Speaker 4: elastin in connective tissue in your vowels.
Speaker 1: So yep, everything's not just on the inside. Here's something inside.
Speaker 4: There's something very interesting about this. So the acquired forms
Speaker 4: can cause or can come from inflammatory skin disorders, drug reactions,
Speaker 4: So pharmaceuticals can cause problems. Ladies, stop taking the boatox
Speaker 4: and stuff because.
Speaker 1: Oh, how about the weight loss stuff.
Speaker 4: H like we talked about on the previous episode, or
Speaker 4: connective tissue degrading following infection or autoimmune stuff. Those so
Speaker 4: those are acquired so you can literally give yourself the
Speaker 4: saggy baggies or the chickens.
Speaker 1: All this stuff.
Speaker 3: Yeah, Like to me, I'm like, okay, listen, you do
Speaker 3: know that's Geela monster poison or the botox is just poisoned. Like,
Speaker 3: quit poisoning yourself. Here's a great idea. Don't take poison.
Speaker 4: And here's the thing. Don't be so vain that you
Speaker 4: think you need the poison and you don't know what
Speaker 4: it's going to do to your body. So just saying
Speaker 4: probably not a good idea unless you want to have
Speaker 4: chicken boob wings.
Speaker 1: Anyway.
Speaker 3: Well, and at some point, look all these people that
Speaker 3: are doing it, and we watch them and we're like, oh,
Speaker 3: they look so great, and look at this person. And
Speaker 3: then they get to a certain timeframe of the plastic surgery, fillers,
Speaker 3: whatever's happening, and it gets crazy and they have like
Speaker 3: tons of money and look at Priscilla Presley ruins her
Speaker 3: face she was.
Speaker 4: There's a lot of people that are like that, and
Speaker 4: you're like, what the hell did you do to your face?
Speaker 1: And that's people that had all the money in the
Speaker 1: world to fix it.
Speaker 4: You guys, like a hundred person like I, yeah, not,
Speaker 4: I'm not signing up for that, No, thank you.
Speaker 1: No. I did bo talk once and I had an
Speaker 1: allergic rea.
Speaker 3: Of course I did, and I got a scar and
Speaker 3: it still like puffs up every.
Speaker 1: Now and again. So I'm good. I don't want to
Speaker 1: try twice.
Speaker 4: I have no desire to do that. And so these
Speaker 4: these phasians again, they're also you know, if they were
Speaker 4: in the side shows, they called a mummies because they
Speaker 4: do look pretty mummified. And so because of this, there
Speaker 4: is no cure, so only treatment. So go get to
Speaker 4: some plastic surgery to fix what you cause.
Speaker 3: I would fix the face, yeah, I would fix the
Speaker 3: face just because dang oh.
Speaker 4: I'm not sure and again, they're like, oh, do physical
Speaker 4: therapy or plastic's or we're just looking in you know,
Speaker 4: go get Jubider or something like that was probably a
Speaker 4: trademark name.
Speaker 1: Sorry about that.
Speaker 4: Any of the things with like the micro needling or whatever.
Speaker 4: It's all the rage, now go do that.
Speaker 3: But it's not gonna help. When it's a literal disease,
Speaker 3: it's help help.
Speaker 4: So these performers, like I said earlier, no names were
Speaker 4: given because they didn't know what these people had. They
Speaker 4: just knew they build these people was specific things. So
Speaker 4: the oldest boy in the world, the boy who never
Speaker 4: grew eighty years, the living death. Wouldn't that be nice?
Speaker 1: Wow?
Speaker 4: The old woman in miniature anonymous exhibits under like I
Speaker 4: said before, the Benjamin Button type thing. So interestingly enough,
Speaker 4: one of the things that I find interesting is I
Speaker 4: was like, I wonder where, like a lot of these
Speaker 4: things come from, because I've literally only seen this glare derma,
Speaker 4: not seeing any of these other things.
Speaker 1: Stool, I didn't know that.
Speaker 4: She did not fart.
Speaker 1: I did not there is a stool. Sure my gosh, yeah,
Speaker 1: I've got the wiggles because problems.
Speaker 4: I'm kidding, it's.
Speaker 3: The one problem I didn't get this back today.
Speaker 4: She We're gonna have to check her for nipples on her.
Speaker 1: Back and yeah, no, my nipples are good.
Speaker 4: So I asked, I was like, what is a summary
Speaker 4: of countries by region that have these the most? So
Speaker 4: prigeriat were actually listed as the number one nation for this,
Speaker 4: which is weird because again, never seen anybody in real
Speaker 4: life with us at any of the facilities I've worked
Speaker 4: at or nothing. Ever, India, Turkey, and South Africa. So
Speaker 4: two of those places are well three of them, three
Speaker 4: of the four are on the list of places where
Speaker 4: do we do experimentation with jibby jabbers and medications so.
Speaker 1: Hmm, and tons of in breeding as well. Ye.
Speaker 4: So the Werner syndrome Japan is the highest, which makes
Speaker 4: sense because a lot of the pictures that we were
Speaker 4: looking at in the slides they were Japanese or Sardinia.
Speaker 4: Italy is the next week, so very interesting that I
Speaker 4: don't know what's going on there. So the Rothman Thompson
Speaker 4: syndrome Europe is the highest. We are number two. Again,
Speaker 4: places that have experimentation going on. Cocaine syndrome is mostly
Speaker 4: Europe or the Middle East. Nothing here, uh, there is
Speaker 4: one called the Bloom syndrome. I don't know what that is.
Speaker 4: We didn't cover that, but it says only in Asconagi
Speaker 4: Jewish populations, so the US, Israel, and Europe.
Speaker 3: I wonder if that's a second name for one of
Speaker 3: the other names, you know what I mean.
Speaker 1: Maybe probably the rapt one bloom.
Speaker 4: Maybe I don't know. I don't know what that is,
Speaker 4: but that's what it put in the chart, so I'm
Speaker 4: not sure. Scleroderma actually here is the highest, which y uh,
Speaker 4: and Europe is the second highest, but mostly in women.
Speaker 4: It doesn't discriminate in the United States. And then the
Speaker 4: Stoneman syndrome, which was the fop stuff. It's equal worldwide
Speaker 4: document in over sixty plus countries.
Speaker 1: And Bloom syndrome, for anybody curious, is a rare genetic
Speaker 1: disorder that causes growth issues, skin rashes and infections. I
Speaker 1: assumed because.
Speaker 4: They's something we covered, but I don't know what that Nope,
Speaker 4: you don't know it by that name.
Speaker 1: Yeah, I think it's probably that other one that you
Speaker 1: talked about. But the rushes.
Speaker 4: Sool interesting weird little oddities. I love doing these because
Speaker 4: even I learned stuff when I'm doing these things, and
Speaker 4: stuff we learn.
Speaker 3: Yeah, this is like being back in school when they
Speaker 3: give you your first medical dictionary.
Speaker 1: You're like, holy shit, real, Yeah, you're like what and
Speaker 1: and to that.
Speaker 3: We're coming up on Spooky season and me and Janet
Speaker 3: have been talking and I think I have a little
Speaker 3: name for for some of the things we might go into.
Speaker 3: It'll still be the Oddities, or maybe it will change it.
Speaker 1: I don't know, but I was thinking ghoulish, ghastly, and grotesque,
Speaker 1: and that might be fun.
Speaker 4: That works well because we got some crazy, crazy things
Speaker 4: to talk about.
Speaker 3: Granted, some of these are already those three words, but
Speaker 3: Jane was telling me about some things that she had
Speaker 3: in mind, and I thought, I'm gonna think about another
Speaker 3: name for that, and I think that might just fit
Speaker 3: the bill for Spooky season.
Speaker 4: So that works perfectly for me because we are definitely
Speaker 4: going to have some some things.
Speaker 3: There's there's be more than just side shows, you guys,
Speaker 3: there is some shit that is real, that is terrifying, And.
Speaker 4: So I so tickled that you do these episodes with me,
Speaker 4: because who else would come on here and you know, talking.
Speaker 3: About talking schoolish and ghastly and nipples and you know,
Speaker 3: stool farts, not stoolism.
Speaker 1: Immediately go to a wrong thought.
Speaker 3: But yeah, we podcasters, you know, especially we have bad
Speaker 3: backs and we need little footstools because you know.
Speaker 4: It makes so much better.
Speaker 1: Yeah.
Speaker 3: I got to move around constantly too, because you put
Speaker 3: the ADHD with chronic pain, You're gonna move a lot.
Speaker 4: I have told be very careful moving a lot because.
Speaker 1: I'll get in trouble.
Speaker 3: But tiger Baum I I don't get paid by them,
Speaker 3: but by some of that.
Speaker 1: It's all natural. It works good, much better than being gay.
Speaker 4: Yeah, that's very true. That does speak like.
Speaker 1: Yeah, I like it.
Speaker 3: It's got a cinnamon e smell and it's more natural.
Speaker 1: So yeah.
Speaker 4: Tip for people if you do use like ben Gay
Speaker 4: blue Emu, like any of that stuff, be mindful of
Speaker 4: the fact that it has menthol in it. Do not
Speaker 4: touch your eyes areas of your body.
Speaker 1: Might end up with with the one lady with no eyes.
Speaker 4: That's exactly right. My eyes are gonna pop right out.
Speaker 1: My oh my gosh. Oh.
Speaker 3: And also I was thinking after spooky season or even during,
Speaker 3: we could do like devastating disasters because there has been
Speaker 3: some ship. My daughter works well, she does it now,
Speaker 3: but she worked in this place where she took care
Speaker 3: of people that only had work related job like issues,
Speaker 3: and one guy got buried a lot, and one guy
Speaker 3: got electrocuted.
Speaker 1: And there's some crazy stories.
Speaker 4: And you know what's funny about that, Like anybody that's
Speaker 4: ever done like, uh, medical coding, this whole section in
Speaker 4: the day, crazy accidents of just off the wall and
Speaker 4: you're like looking at him, going, how in the hell
Speaker 4: would that?
Speaker 1: How did you do this?
Speaker 4: Yeah?
Speaker 1: What did you do? Why?
Speaker 3: You know the first lobotomy ever done, you guys, And
Speaker 3: this is a real story. The guy accidentally shot himself
Speaker 3: in the eye with a nail gun and it went
Speaker 3: clear through and this is how they figured out we
Speaker 3: could make people lobotomized like this because he was never
Speaker 3: the same again.
Speaker 4: So that's that's a great idea. Yeah, that as regular
Speaker 4: tools for people.
Speaker 1: Yeah, well some people need it in.
Speaker 2: Yeah.
Speaker 3: Actually that was the other one right up the nose
Speaker 3: and in the eye. There's like two ways. There was
Speaker 3: two different accidents, so anyway, it gets weird.
Speaker 4: That's some crazy stuff.
Speaker 3: That guy was an ice pick in the nose, wasn't it.
Speaker 3: How do you have an ice pick up your nose?
Speaker 1: Like, what are you doing that?
Speaker 4: You are you running with an I.
Speaker 1: I think I might have been first.
Speaker 3: Yeah, I don't like, I don't know what you're doing,
Speaker 3: but it seems like those are a weird place to be.
Speaker 4: I don't know. We can do a whole episode about
Speaker 4: things people insert as well.
Speaker 3: Oh lord, I have had as an ear nurse so
Speaker 3: many interactions with this, And let me tell you all
Speaker 3: one thing. Don't use people's remote controls unless you know them. Well,
Speaker 3: bring some iceol or something.
Speaker 1: I don't know. You're safe at my house, your mark
Speaker 1: safe on the remote controls because weird. They make Coles
Speaker 1: stores to sell shit like this. Now you can even
Speaker 1: have it delivered in the privacy of your own home,
Speaker 1: and we're still digging shit out of people, so.
Speaker 4: In a plain brown wrapper. Oh the funny thing is, okay,
Speaker 4: I went shopping yesterday. I always go to Ben's stores,
Speaker 4: and I'm like looking around for things to you know,
Speaker 4: put like together baskets for charity and all that stuff,
Speaker 4: And a lot of times they have boxes and you
Speaker 4: don't know what's in the box. And I was like,
Speaker 4: I don't know. Well, some lady like I gotta grab
Speaker 4: bag some lighty grabbed a like a knife out of
Speaker 4: her purse slipped this box open or whatever. She looked
Speaker 4: at it and walked away. So I grabbed the box
Speaker 4: and peeked in it, and it was a giant Oh,
Speaker 4: you're like WHOA. I was like, I'm not. I don't
Speaker 4: want to charity basket, although I.
Speaker 1: Mean, I'm just kidding. Oh my gosh.
Speaker 3: You know, people, I won't judge you if you buy
Speaker 3: something that belongs there, but I will certainly. I had
Speaker 3: to leave the room one time, and I won't say
Speaker 3: it now, I'll save it.
Speaker 1: And because I was gonna hysterically start laughing, and I
Speaker 1: was so trying hard not to because this person was
Speaker 1: not okay. But I had to leave the room.
Speaker 4: And I've had that kind of stuff happened too, So.
Speaker 1: I don't know.
Speaker 4: We are both quirky and weird, so you never know
Speaker 4: what the hell the topics we're going to have on
Speaker 4: a future show.
Speaker 1: Ladies, you won't want to miss it, that's for sure.
Speaker 4: Grab your popcorn because it's always entertaining with us.
Speaker 1: Yes, you know what, we got chicken tits and yeah,
Speaker 1: all kinds of things. Yeah.
Speaker 4: So, miss Heidi, I love you so much. Thank you
Speaker 4: for joining me for another episode in our side show
Speaker 4: Attraction series, tell everybody where I can find you at
Speaker 4: my Love you Bet.
Speaker 3: I am Heidi Love of the Unfiltered Rise. I'm everwhere
Speaker 3: podcasts are served. You can do a search up luv
Speaker 3: on YouTube or whatever for any guest appearances, but the
Speaker 3: most place you will find my things is either on
Speaker 3: Patreon or on Spotify. And yes, YouTube does get some drops,
Speaker 3: but not nearly as many, so find me there and
Speaker 3: check me out. And miss Janet for those that don't
Speaker 3: know you, please let my viewers know where to find you.
Speaker 4: You can find a plorabal Nation on every podcast platform,
Speaker 4: plus videos are available on Spotify and on Rumble. And
Speaker 4: if you like Christian music, go check out Anchor and Flame.
Speaker 4: That's the and with the hand sign on all kinds
Speaker 4: of music platforms, because that's my little baby that I'm
Speaker 4: working on, So go check that out. If you want
Speaker 4: to hit me up for a show or have comments, questions,
Speaker 4: anything like that, you want to tell us how awesomely
Speaker 4: wonderful we.
Speaker 1: Are, We're any great ideas well.
Speaker 4: Exactly or any great ideas feedback on shows, feedback for shows,
Speaker 4: hit me up on Instagram at deplorable Janet or on
Speaker 4: Twitter at no Janet Kate in Ow.
Speaker 3: And give us a five star on Apple. I know
Speaker 3: it's annoying to have people say this, but it's the
Speaker 3: only way we can stay on top of the algorithm.
Speaker 1: And for two ladies.
Speaker 3: Out of the whole podcast community, I don't know how
Speaker 3: many others are even left right now.
Speaker 1: Yeah, help us out.
Speaker 4: It's a small pool and we're big shark swimming in
Speaker 4: a tiny pool, so we need more water.
Speaker 1: Please.
Speaker 4: Thank you so for me and for the wonderful, amazing
Speaker 4: Bessie from the Westy Miss Heidi. Thanks for tuning in
Speaker 4: and we will see you next time. Have a fantastic
Speaker 4: day and don't get wrinkled.