Speaker 1: You were listening to petlife Radio dot com.
Speaker 2: Well, welcome, welcome, welcome, hopefully to another fun filled half
hour here on pet Life Radio. I asked the best
of doctor Jeff. I am your host, doctor Jeff Warber,
and I'm here to talk about anything. I mean anything
really dog and cat, preferably because that's my bag. But
if I don't know the answer about something else, we
will get it for you. Talked about last week, talked
about Henry, who is by the way, doing amazingly well.
Of course, we have to thank our sponsors pro Tens
Pet Products, and we are trying to bring you a
veterinary quality product at a price that you can and
available at your local retailers as well as Pet Health Network.
It's one of my blog sites, and I have a
lot of friends and colleagues that blog on Pet Health
Network and you can just get so much great information
how to be the best pet owner, pet parent. Call
yourselves what you want you can be, and we want
to hear from you. And it's very easy to get
a hold of me. I'm going to give you a
number of ways. Number one probably the easiest call me
eight seven seven three eight five eight eight eight two
you can also if you're listening online right now to
pet Life Radio, there is a little chat box you
can just go on to the bottom that says click
year to join the conversation. Go ahead and join that
conversation and we can talk. And lastly, you can send
me quick email.
Speaker 3: To Dr Jeff.
Speaker 2: That's doctor Jeff at petlife radio dot com. So, first
of all, we had spoken to Sarah. She read an
email and she just answered back, I'm gonna read it
to you. It says it's she did just what I
want you to do pet Life Radio. She goes, thank
you so much for your suggestions. My twelve year old
Westipoo flower did indeed have a your night track infection
and is now an annibatus to clear that up. She's
back to her old self. I have a new question
for you. I listened to your podcast while I drive
my mail truck in a Chicago suburb. Can you imagine
how tough it is to drive that struck around?
Speaker 3: Anyway?
Speaker 2: I was recently listening to a show from a few
months back when you mentioned a new allergy medication to
be released hopefully in January of this year. Can you
please share the name of this product? Flowers suffered from
skin issues due to allergies for most of her life,
and we're now looking at starting her on accutane. I
know that this drug is very hard on the liver,
kidneys and humans, so if there's something new to try instead,
I would rather try that. Thank you again, doctor Jeff
From Sarah, Well, Sarah.
Speaker 3: You are in luck.
Speaker 2: Maybe why maybe this drug did hit the market in
January was released and because.
Speaker 3: Of its amazing and I mean amazing.
Speaker 2: Success, and I can attest firsthand because I have a
number of patients on it already. The company which is
Zoetis now Zoetis is formerly Pfeiser Animal Health. Pfiser Animal
Health Group broke away from the parent company, which was Pfizer,
and they are their own company called zoetis doing extremely well.
And the new drug that we talked about is called Apoqueil.
That's a po quel. It comes in three sizes, three
strains basically for different weights of dog. And it really
is amazing and I'm gonna explain how it works in
a second. But the one problem is already, because of
its amazing success, probably faster than they had expected anticipated,
it is now tough to get. They are already back ordered.
They are obviously keeping patients that are already on it
to stay on it, and it is it's just an amazing,
amazing medication. So here's basically the nuts and bolts how
it works. I don't want to be too scientific, but
as we know, in humans, the allergic response is mediated
by a cellular mediator called histamine, and therefore when we
want to block that allergic response, we take anti histamines. Well,
histamine does not play a major role, much any role,
very minor role at best in the canine allergic response.
So therefore we don't recommend taking antihistamines, certainly not for
the anti allergy effect. However, sometimes we do recommend some
of the good old fashion antihistamines like benajol, which is diphenhydromene,
like ataracs, because those which is called hydroxyzine, will have
a bit of a sedative effect, and I think a
lot of the allergists that we're using the nonesedation type
of anihistamines, we're finding that they really didn't work that well. Well,
the search for years has been on how do we
find out what exactly is happening in the canine allergic response?
What is making literally them itch, what is making that
skin get inflamed? So the folks at Zoetis have been
studying this for quite some time, and the basic physiology
is that there is a type of white cell called
the T cell. The T cell is a cell that
is a cell that responds to antigenetic stimulate. The T
cell releases and agents that are called cytokines, and there's
one that are interlukens, and the interlukens the are number
of them that are involved in the allergic response two, four, six, thirteen,
and thirty one and interraluken or IL thirty one seems
to have a pretty major role in the allergic response.
But in order for the IL thirty one to do
its thing, to actually cause the body to itch, cause
that inflammatory response, it needs the help of an enzyme
or actually a couple of enzymes that are called janis
kinse enzymes, and for short we call them JACK and
the two enzymes that are very very important for this
response to happen are JACK one and JACK three, And
the new drug called apoquil actually blocks the Jack one
and the Jack three enzymes. So therefore, even though those ils,
those interlukens are just dying to do what they do
to make our dogs uncomfortable. Without the help of the
jack enzymes, now blocked by aplequil, they can't, so it
is literally amazing, and the beauty of it is it's
not like the cyclost foreign which many of us have
had to resort to put our dogs on, which is
an immunosuppressive agent. It's not like the Cordi zones, the
pregna zone which has been the industry standard, which also
potentially though it has excellent anti inflammatory effects, it also
can cause immunosuppression at higher doses, and there are a
lot of other conditions that we know from long term
steroid use, so we can't use it long term. In fact,
when we have to resort to using corticosteroids, pregna zone
being the most common for the dog, we often have
to go on alternate day therapy. So we start with
like twice a day, made that for a few days,
I we'll go to one a day and ultimately settle
it every other day because there are too many side
effects with everyday therapy. Well, with the apoquil, it has
now been tested for years. First of all, it's been
used in Europe for years and here in the States
to get through FDA approval, which it has done a
lot of the specialty groups. In fact, one of my colleagues,
who is a board short of veterinary dramatologist, has had
her own dog on apple quill now for four years
every day with zero side effects.
Speaker 3: So it really is. It's an amazing drug.
Speaker 2: So Sarah, talk to your veterinarian if he or she
is lucky enough to still have any on the shelf.
It's called apple quill, and it might be the perfect
medication for flower. With aplequill, you can use antibotics, you
don't need to use steroids, you do not need to
use the cyclosporins. There are some drug interactions which your
veterinarian can share with you. We also want to use
it only in dogs that are over a year of age.
But as far as safety and dogs that I know
personally that have been on very long term, it is
just amazing.
Speaker 3: So I understand. We have a caller. Hello, are you
on with us?
Speaker 4: Yes, I am Hey.
Speaker 3: How you doing?
Speaker 4: I'm good? How about you?
Speaker 3: I'm doing great. What's your name?
Speaker 4: My name's Scott.
Speaker 3: Hey Scott, So what can I do for you?
Speaker 4: Well, my wife and I are talking about adopting a
dog sometimes in your future, and we just want to
know quickly, you know, when you would recommend having them
space at what age is that appropriate to do?
Speaker 2: Okay, So, first of all, it's a great question, and
I really appreciate the fact you're adopting narios. Tell people,
you know, save the breeding for the breaders and go
out and adopt. You know, you're going to save a
life for sure, So if anything else, in addition to
the wonderful addition to the family, you're going to save
a life now a lot of times, just so you know,
many adoptions facilities across the country, I think, for a
pretty good reason will not even release a dog until
it's already spader neuter. I have some issues with that,
depending on the breed, but it is just the way
it is. It used to be you would adopt a
young dog and you would get a voucher and you
then when the dog is ready, you could take that
voucher to the local Spain neuter clinic or the hospital
that works with that adoption agency or the shelter and
get the neuter or stay for free. The problem is
that most pet I wouldn't say most there are many
pet owners or new pet owners out there, probably not
as much chancious as like you would be, and don't
care about the voucher and just keep their dogs and
the dogs hit the streets and then a breed and
you know, all these bats can happen. But let's talk
about the perfect world. In the perfect world, if you
had the ability, I would recommend the following. I don't
like spaying and neutering any dog before six months.
Speaker 3: Okay, here's the reason.
Speaker 2: The dogs that you can safely spay or neuter young
before six months of age or around six months of
age are the small breeds. And the small breeds, however,
have another very common issue that we often have to
deal with, and that is called retain deciduous teeth.
Speaker 3: They don't lose.
Speaker 2: Their baby teeth on schedule. When the adult tooth erupts,
it is supposed to push the baby tooth out of
the way, and therefore it's a tooth replacement. The baby
falls out and in that same socket and the gum
line the adult comes in. Often, however, with the small breeds,
that doesn't happen, and the roots of those baby teeth
are so long that they hold their ground and it
forces the adult tooth to come in in an inappropriate position.
But you now have double teeth, so we need to pull.
Speaker 3: The baby tooth.
Speaker 2: We're not gonna know which of the baby teeth are
going to require extraction until all the adult teeth are in.
And when does that happen. That whole process is done
by five and a half to six months of age.
So if you take that little Yorki or a little
multi pool whatever, and you spay her or new to
her at four months, which you can do, is a
very good chance that comes six months, you're gonna have
to knock her out a second time to pull the
baby teeth. And that's insane because the most dangerous part
of these procedures is the anthesia.
Speaker 3: Do you want to do it twice?
Speaker 2: So therefore I prefer holding off the small breeds, even
though it be okay to do until they're at least
six months of age.
Speaker 3: Now let's talk to large breeds.
Speaker 2: I used to feel the exact same way, and I
used to use the same schedule. Large breeds, wait till
they're six months, get the females at least before their
first heat, which is at seven months of age, if
they read the book, and therefore you will virtually eliminate
any threat of mammary cancer. And everyone is happy. But
we learned something new recently, and when I say recently
in the in the medical world that can be back
within even two or three years, and that is that
there was a study out of one of the veterinary schools.
I don't want to misquote myself. I think it was Purdue,
but I'm not guaranteed where. They were studying aging, and
they were using the Rottweiler as their model, and the
theory was that they had never seen a pure rottweiler
hit thirteen. Whether it's true or not, I don't know.
But in the midst of their study and studying all
aspects of aging and the bloods and the bone and
all these things, they came upon a very very frightening statistic,
one that I think surprised them as much as it
did me when I read it, and that is they
found a sixty five percent greater incidents in long bone
cancer in males that were pre pubertly neutered, and a
thirty five percent increase in females that were pre pubertly spayed.
That is so amazing. So that tells us that there's
got to be We hadn't understand the mechanisms, but there's
got to be some protective effect of the sex hormones
on developing bone that is going to protect that bone
eight ten years down the road from developing cancer. Bone
cancer is a killer one hundred percent. So therefore, if
I can do something that is gonna slow down that
process or help sixty five percent chance of not getting it,
you darn right I'm.
Speaker 3: Gonna do it.
Speaker 2: So therefore, my new recommendation for the large breeds, and
these are all the large breads, because these are all
dogs that are prone to bone cancer as older dogs,
is I'm waiting. My new recommendation is a following small breeds.
If you can control it, you can spay them six months.
Try to get your females just before their first heat.
I'm okay with it, but make sure you do it
after all their adult teeth have erupted. The large breeds,
I'm waiting a year. I'm waiting a year. Let the
female have her first heat. You can still make a
dramatic reduction in a memory cancer if you spay her
after her first but before her second heat, that comes
at around fourteen months of age. So therefore my recommendation
is spay. Those large breed females are eleven or twelve
months of age, so they've already sexually mature, so you're
gonna hopefully help the bone cancer issue, but you're still
getting them where you can make a big difference in
their memory cancer issue. The males you can wait almost
any time. I would do a year only because with
the males, especially the big breeds, I mean, let's face it,
a male is a male. You know, they're gonna be
picking up the sense of those and the pheromones released
by the females in season, and they are going to
be sending flowers and wine to those bitches and heat
and you know, and and they're gonna be roaming in
the streets at dogs sound and US roads and highways
are non neutered males.
Speaker 3: So did that to help you?
Speaker 4: Definitely? Yeah, thank you, Thank you for all that. I
appreciate it.
Speaker 2: What type of dog or size wise are you thinking
of adopting big or small?
Speaker 4: You know, probably somewhere in between. My wife, you know,
I like big dog in my wife solways like small dogs.
So I think we're gonna kind of compromise. You know
something you know, maybe like a little bigger than corny.
Speaker 2: You say, okay, so just keep one thing in mind
if you get a get mine, but it was just great.
For example, you know the big crosses now are the doodles,
and there are now you can get many like labberdodle
or golden doodle.
Speaker 3: Don't kid yourself.
Speaker 2: The retriever part is a dog that does carry the
bone canter gene. So even though you get a mini
which or you know, which means that it might be
hit only hit twenty five to forty pounds, it gets
killed carry that gene. So I would still follow the
rule of the larger dog if you know that in
the breed mix that you're getting, even though you might
be a small version of it, if one of the
parents was a larger dog, I would stick with the
one year.
Speaker 3: As far as fixing.
Speaker 2: If you can, I just said it might be tough
because some of these shelters and rescues won't even let
you have them until they're fixed. And if that happens,
you got to go with their rules. But you know,
what can you do anyway? Scott, thanks for the call in.
If you can do me favor and either call back
and talk to Mark. I want to get your name
and address, and we are going to send you out
a free pro Sense product. Probably since you are getting
a new dog, we'll send out a pro Sense pack
of itamins for your new pump to make sure that
here she stays healthy all the time. And thanks for
the call, and it is time forrop breaks and we'll
be back in a few minutes. Thanks for listening in
and stay tuned. We'll be back in a few here
on pet Life Radio. Ask the vets with doctor Jeff.
Speaker 1: We'll be right back right after these messages. Stay tuned.
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Speaker 1: Petlight Radio dot.
Speaker 2: Com and welcome back. You are listening to doctor Jeff Werber,
your host here on.
Speaker 3: Pet Life Radios.
Speaker 2: Ask the bets with doctor Jeff and we want to
hear from you, just like Scott just called in. Hopefully
we can help. If nothing else, just think about it.
You get free advice and a free pro sens product.
What could be bad? So you can reach us here
at eight seven seven three eight five eight eight eight two.
You can reach us also just online here by joining
in on the conversation and finally send me an email
to Drjef. That's doctor Jeff at Petlife Radio dot com.
So we helped Sarah with and hopefully you all learned
about the new apical medication. I think it's great. I'm
gonna be working actually with them. I got was fortunate
enough to be asked to do their media campaign when
they hit the national media tour, which will be coming up. Well,
they were hoping to do it in spring. I was
just to do it like late March early April. Is
because the drug has been so amazing and so successful
and they've been having such a tough time keeping up
with the demand. They didn't want me to do the
national media launch. And that means to you the consumer.
So there are two reasons that The initial reason why
you want to always hold off on a new product
like that is you don't want the consumers, you guys,
to know more about something in the veterinarians. So whenever
there's a new product out like this, they want to
spend the first several months priming, educating, and promoting this
to the veterinarians. So if nothing else, even though the
veterinarian choose is not to carry the medication. I have
no idea why, but many are very very shy about
brand new medications. At least they know about it well.
They know about it so well that they've sold it
off the shelves. So it looks like we're going to
do our campaign coming up in a late spring early summer,
and it's fun for me.
Speaker 3: It's called a national.
Speaker 2: Media tour where I probably get to go to New
York and work in the studio and talk to the
big national magazines and really educate everybody, educate the masses
about the benefits of apaquil and the benefits of apple
quil over some of the drugs that we've been forced
to use over the years. I mean, we're talking excellent
drugs like pregnant Zone certainly has its place in medicine
and veteran medicine, but we also has its disadvantages, and
the same thing with cyclosporins. So I'm looking forward to
that and you will certainly over the next several months
be hearing more and more about aplequil. And then we
talked to Scott about a subject near and dear to
my heart, and that is Spain Hooter adopting. We hit
it all in one phone call, and that's great because
we know obviously love to help these animals. In fact,
we've been talking about Henry over the last couple of weeks.
Henry is that the American eskimo that was found on
streets here in Los Angeles that was mauled by something
or some things. Don't know whether they were much larger dogs,
don't know where they were, coyotes, But this poor dog,
but the fact that most of its injuries were literally
around its neck, where its entire neck was ripped open
down to and including the trachea. It's amazing that his esophagus,
his carotid artery, and jugular vein were not severed like
all the muscles and the other tissue and his trachea.
So instead of putting him to sleep, which was really
our initial recommendation because he was really really suffering, and
the road ahead was very, very long and expensive. Even
at the break we give rescues. Because of the Good
Samaritan Act, we sort of were forced to at least
keep this guy going. We did a major surgery and
sewn up is drachia and cut away all the democratic tissue.
Speaker 3: Here we are three almost four weeks.
Speaker 2: Later, and Henry is doing amazingly well. He is probably
has one more surgery we're waiting on until we get
a better what we call a granulation bed. We want
the body to do what it's going to do and
do it really well, and then he's going to have
a new home.
Speaker 3: He's doing just.
Speaker 2: Great, and I'm thrilled as much as I still you know,
I always have this discussion with our rescue groups, these
bleeding heart rescue groups, about how they want to save
every single one, and I try to educate them that
you can't and take that money that you would spend
and spend it on saving hundreds of others, that if
they don't get out of this shelter, they're going to
be put to sleep. Unfortunately, here in Los Angeles and cities,
there are not enough no kill shelters. They just can't
afford to be no kill. But nonetheless, Henry is a
success story. We're doing something. We're going to put him
up on our blog on pet Health Network, which is
by the way, I want all you to visit pet
heealthnetwork dot com, and I'm going to be posting some
pictures before during and after pictures of Henry, so you
can clearly see how amazing this dog is and just
what type of fantastic recovery's had. Then next week, I
and also my good friend Mark Winter from Pet Life Radio,
we're going to be in Orlando at the Global Pet
Expo and that's where we get to visit the pet world.
And I just came back from two big veterinary trade shows,
one in Orlando, interestingly, and then the following month in
Las Vegas. And now we're going to the Pet world,
which is where I work with my product line, the
pro Sens Pet Products, one of our sponsors of this
radio show. And also just see what's new and innovative
in the pet world.
Speaker 3: And it's amazing.
Speaker 2: This exhibit hall is huge, that's convention center, and we
really get to see there is so much innovation, so
many great things going.
Speaker 3: On in the pet world.
Speaker 2: And you know, it's great to see the economy having
bounced back to the point where we have these large
companies doing so much to help make life easier for
you and your pets. And I'm always intrigued by some
of the new things out there. You know, again, behavior
is always a big problem so to see some of
these companies coming up with these toys, these games, literally
games that dogs can play in your absence, that keep
them stimulated, stop them from barking, help them with their
separation anxiety, almost getting to the point where they are
not so dependent on you for their health and well
being that they can do it on their own. Those
things are great. So when I get back, we will talk.
So next week I'm going to be at the show,
but the following week we are going to be live,
and I'm going to share with you some great things
that I found at the Global Pet Expert Show in Orlando.
Speaker 3: So anyway, it is time for me to go.
Speaker 2: This half hour go so quickly, so once again, thanks
for joining in and tuning in.
Speaker 3: We will see you or.
Speaker 2: You'll be visiting with me live in two weeks here
on pet Life Radio Asking Beat with Doctor Jeff and
we will see you.
Speaker 3: Then, have a great week.
Speaker 1: Let's talk bets every week on demand only on Petlifradio
dot com.