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Speaker 1: You were listening to Petlifradio dot com.

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Speaker 2: And welcome, welcome, and have me Sunday to all.

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Speaker 3: Good morning if you're out here in the west by

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me or good just break it that afternoon if you

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are in the east, and hope all is well with you.

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We are enjoying a nice, clear, beautiful day out here.

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Hope yours is the same. Very curious to know how

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how everybody did Halloween wise, you know, it's interesting here.

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I am promoting all the things you need to do

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and all the things you need to be careful of.

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Speaker 2: We talked about a lot last week.

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Speaker 3: So what I usually do for my office is I

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will bring some candy just for my clients. You know,

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we put them out on the counter in the front.

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So I had I had two bags. One was Nessi's crunch,

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one of mine. I always get my favorite that way.

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Don't eat him a least. I'm going to enjoy something

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that's left over. And snickers. Well, I had the bags

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here in my home office. Now, mind you, my dogs are,

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especially my labradors, are insane when it comes to getting

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into things. They are masters and I literally have to

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have baby locks on cabinets because they know how to

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get into cabinets, and I have to block the kitchen

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door so they don't get into the kitchen if they're

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in the house anyway.

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Speaker 2: So I had.

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Speaker 3: Totally didn't realize they were in my office. I forgot

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that's safe because they never go into my office. All

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of a sudden, I get a call. I forgot to

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bring the bags, and there's my lab, my old lab,

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thirteen and a half. Now, mind you, this guy can

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barely get upstairs, but he could jump on top of

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a counter for food.

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Speaker 2: Anyway.

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Speaker 3: He gets into about ten of those little teen nesties grunds.

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Speaker 2: He's eighty five pounds.

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Speaker 3: I'm not worried about the toxicity issue with milk, chocolate,

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et cetera, et cetera. But you know, he doesn't like

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to take things out of rappers. He thinks, you know,

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I'm gonna smell it right through the wrapper. I'm gonna

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eat the whole thing. So I knew this happened. I

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figured some of the stuff would come out of his poop.

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I wasn't too worried about it. Since then he ate

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like what. So that was Friday morning early, he ate,

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Friday evening, he ate Saturday, Saturday morning right ate all

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these meals, and late last night I hear him up chucking,

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and I hear that typical you know, that vomiting thing,

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and outcome that mind He's had normal meals and normal

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poops over this last day and a half, and all

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of the rappers in a bunch came up in his vomit.

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It's like, I'm thinking about, how does the food get

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by and go through the intestine and get digested. It

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all is fine and develop a nice verso and the rappers,

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the Nessie's Crunch Rappers are still there in their entirety. Anyway,

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I hope you guys had better luck than I did.

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As I used to say to my kids, do as

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I say, not as I do, because I'm the worst

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lesson to learn from when I do stupid things like that. Anyway,

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I'm glad you're here with me. I'm doctor Jeff Weerber,

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your host for today's Ask the Vets with Doctor Jeff

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here on the pet Life Radio and iHeart Radio station partner.

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Speaker 2: And we're here for you. In fact, it's easy to

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get ahold of us.

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Speaker 3: And last week we did get a call, well actually

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someone wrote in joined in in the conversation, which you

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could easily do. If you are shy and you don't

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want to call us at eight seven seven three eight

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five eight eight eight two, you can just go online

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to petlifradio dot com, click on Ask the Vets with

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Doctor Jeff tab and on that page you will see

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a little box that says join the conversation. Log into

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our live chat during the show.

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Speaker 2: Please do so.

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Speaker 3: Last week we didn't get someone who called in.

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Speaker 2: And also you can.

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Speaker 3: Email me to Dr Jeff. That's doctor Jeff at pet

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Life Radio. And you know, look, we want to make

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your lives easier. Just think about all the benefits the

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benefits of joining us either via phone or joining the

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conversation the following hopefully you're going to get some answers

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to your questions. And if I don't have the answers,

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I will get them. As a general practitioner, for this

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is my thirty first year, I kind of know a lot,

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but when it comes to really tough things, I have

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a great network of experts in pretty much every specific discipline,

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so I will get an answer. Secondly, it's free, doesn't

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cost you a time. My goal here is to help

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you and maybe even help you save a little money

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in the process, and of course we're here thanks to

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our sponsors, pro Tense Pet Products and cong As a

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matter of fact, when you call, not if, but when

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you call, when you join in on the conversation, we

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will send you out a pro Sense pet product as

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well as a free Kong toy. And contoys are great

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because they're therapeutic at the same time, So you have

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no excuse, no excuse not to join in. So first

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of all, I would love to hear about any Halloween stories,

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the good ones and the bad ones, if you had

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a problem, if you had a dog that got out,

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if you had a cat that got out, if you

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had dog that was growling at some of these kids, whatever,

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we want to know about it. So again eight seven

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seven three eight five eight eight eight two, you're just

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kind of joining in the conversation and we'd love to

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hear from you what I wanted to do. And we've

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been sort of going through and until you contact me

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to speak about a specific subject, which I'm happy to do.

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Speaker 2: I have a game plan.

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Speaker 3: My lesson plan, as you will, is if I were

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a teacher, and what we're going to do now is

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we're going to cover the very many endocrine diseases. These

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are diseases of the hormone system of the body that

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seem to go astray and ry at certain points. And

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most of these are fairly easy to diagnose.

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Speaker 2: Some are more difficult.

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Speaker 3: Some of the growth hormone problems could be very tough,

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but they're somewhat easy diagnosed, not always easy to treat.

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Speaker 2: Very fewer curable.

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Speaker 3: However, we can control them. There are great medications, great

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choices we have. Some, believe it or not, are pretty

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much curable. When you're done, you don't have to do

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a thing. But those are the rare ones. But we'll

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get to all of them. So what I wanted to

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do is, we have a land in our body called

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the adrenal gland. It is basically attached to the crania

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poles of our kidneys, and the adrenals have different zones

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within the gland and they're responsible for the sex hormones,

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for the mineralid corticoids. Those are the hormones if you will,

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that will control the mineralid corticoids, which are like our

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calcimine phosphorus balances, and so you know that's very important

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for the body. Sodium potassium also very important to the body,

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and also the glugle corticoids, which are the steroids that

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are body secretes. Basically, I'm sure you've heard of a

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drug pregna zone or any of the corticosteroids that are

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used to treat many conditions and pets in different dose

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ranges depending on whether we need an anti inflammatory component

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or whether we need to have an iminosuppressive component, So

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there's some different dose ranges. The adrenal plays a major function,

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and the signal for the adrenal to work usually comes

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from a gland in the brain called the pituitary gland,

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and there's a number of feedback mechanisms where the body

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is able to read what's already there and then with

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a healthy gland make necessary adjustments and whether it's going

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to make them on its own or make them as

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a result of secretion from the pituitary gland. So the

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petutary gland sort of is the master gland that dictates

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for the adrenal what to do.

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Speaker 2: Well.

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Speaker 3: There are two conditions that we frequently see and also

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the effects are a little bit different where concerning the

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adrenal gland. Where one is an over secretion of the

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adrenal gland, and the other one is an under secretion,

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and the one that we see more commonly is the

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over secretion, and we call this Cushings syndrome or cushions

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disease technically. And the Cushing's syndrome is actually where the

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problem is coming from the brain, the petuitary gland, and

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the petuitary land is overfiring, over signaling the adrenal gland

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to secrete it's glucocorticoids, not really listening to the rest

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of the body when the body says, hey, slow down.

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We got plenty of cortisol running around our blood. We

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don't need anymore. It just keeps on firing and signaling,

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and that is Cushing syndrome. Cushions disease is where the

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problem is actually coming from the gland. The adrenal gland itself.

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Ptuitary has nothing to do with it. It's all coming from

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the gland. There's a functional increase of secretion coming from

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the adrenal and that's Cushing disease. The reason why there

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is somewhat of a difference is that when it comes

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to treatment, when you can I clearly identify Cushion's disease,

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it might be easier, well not easy, but it can

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be treated by removing the adrenale. Obviously, that can require

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the hands of an excellent technical hands of a surgeon,

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but can be done. Whereas, obviously if the peturit arry

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is the problem, so it's really by definition Cushing's syndrome,

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you can't do that. So that's that we have to

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rely on medical therapy. So what are the symptoms? And

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this is what's so important because a lot of the

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symptoms that we see with some of these hormone diseases

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are very similar. For example, a dog comes in and

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it's classic cushings. I got a funny story about my

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early days in practice with this condition, and it is

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a dog that comes in and the complaint, the chief

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complaint from the owner is my dog is drinking water

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like crazy and peeing like crazy. Now there is another

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disease we're going to get to, not probably not this week,

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but maybe in a couple of weeks, and that's diabetes.

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Two types of diabetes, diabetes melodists and diabetes and simpetus.

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And guess what they too present with dogs that are

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drinking and being like crazy. So cushions disease typically we

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call it pupd polyuria that's excessive urinating, and polydipsia, which

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is excessive at drinking. Other things we see with cushings.

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We see kind of like the body is changing. The

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skin is getting kind of thin and oily. Sometimes we'll

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see hair loss that's not associated with scratching the skin,

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the belly looks bloated. Basically, a lot of the changes

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we see are the same changes we're going to see

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in a dog that we have to treat with an

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excessive amount of cortico steroids for whatever disease they may have.

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So when I'm sure you've seen people that had to

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be on steroids for a long time, it's similar type

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of changes take place in the body. So you get

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that thin, sometimes greasy looking skin, thinning hair, big, bloated belly, pup,

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the excessive drinking, excessive pin and you say to yourself,

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oh my god, this is classic cushings. Now, to this point,

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you still don't know whether it's cushions disease or a

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cushing syndrome, but it's cushings. So now the fun begins,

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and that fun is we need to start doing some

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tests to see where are problem is and to try

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to make a determination because the disease actually is not curable,

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but it is treatable, it is controllable, and we have

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many cases that dogs with cushings that are just doing

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just fine. There is actually a relatively new drug. When

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I say relatively in vetterney world, that means that it's

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not like yesterday, but it's been around for probably seven.

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Speaker 2: Or eight ten years.

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Speaker 3: Maybe it is a major improvement over the drug that

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we used to use back in the day when I

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started practicing. So there's some new things out there that

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are great. Also, testing, one of the tests that we

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used to use is still used often, but there's no

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other test of many of the experts like a little

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bit better, so we use that one too, And this

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other test, the one that's a little bit better, might

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actually help us determine the difference between cushion disease and

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cushing syndrome. And of course, with the advent of ultrasound

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in the hands of an amazing ultrascenographer, the adrenal gland

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sitting bite by that kidney is often visible and it

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can be measured, and a determination can be made merely

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an ultrasound whether we're dealing with the adrenal problem.

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Speaker 2: Or the pituitary problem.

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Speaker 3: So there's a lot to do, a lot to talk about,

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and we will as soon as we come back from

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our quick break, So stay tuned. We're learning about cushings

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disease in dogs predominantly, and we'll be back in just

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a few and we'll talk about testing and we'll talk

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about treatment, and we'd love to hear from you if

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you have any questions about your dog that may have

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or might your concern might have cushings or is currently

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being treated. We'd love to hear from you and get

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your input as well. Here at eight seven seven three

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eight five eight eight eight two. We'll be back in

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just a minute.

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Speaker 1: We'll be right back right after these messages. Stay tuned.

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Speaker 4: This is my tired of itching face.

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Speaker 3: Does your dog suffer from persistent itching and scratching? Allergies

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and skin irritation is caused by environment, including pollens, insects,

246
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especially please, food and common household allergens are common problems

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250
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you for That's love Life. Love them back with pro Sens.

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Speaker 6: Pet Life Radio, the number one pet radio network on

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Speaker 7: Hey there, pet parents, this is Christy Vaughan post of

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The Doggie Dish. Do you love your furry companion? Do

280
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you love making him or her healthy treats but can't

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Doggy Dish for yummy and healthy recipes for your canine kids.

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Speaker 1: Every week only on Petlifradio dot com. Let's Talk past,

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00:14:04,399 --> 00:14:07,360
Let's done, pet Talk about Life Radio, Hetline Radio.

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Speaker 8: At live radio dot com.

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Speaker 2: And welcome back and thanks for being here.

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Speaker 3: And you're here with doctor Jeff Werber, your host here

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on Ask the bect for doctor Jeff here on pet

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Live Radio. And before the break we were talking getting

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a little science here education about a disease we commonly

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see in dogs, I shouldn't say commonly with innive medicine

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or in medicine in general, we get to use the

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term it's not uncommon. Now usually if you look at

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it double negative. Well, if something is not uncommon, you'd

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say it is common. But common means it happens a lot.

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In medical ease, when we say it's not uncommon, it's

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just this means uncommon is something you rarely see. So

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if it's not uncommon, it's not that we don't We

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don't not rarely see it.

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Speaker 2: We don't see it a lot.

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Speaker 3: It's not common, so you kind of Yet, you have

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to be very careful in using the term. So when

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we see something it's not uncommon, I mean, yeah, we

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see it. We see it, you know, kind of frequently,

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but not not a ton. But it's not surprising. It's

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not like you know, my old expression I've shared with

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you before that you're running along the beach, and I'm

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gonna use Malibu because I'm here in southern California. Say

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you're running along the beach in Malibu and you hear

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hoof beats chasing you from behind. Are you thinking horses

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or zebras? So you're not thinking zebras, so you're thinking

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horses now. So therefore, when I say something is not uncommon.

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Speaker 2: It's not a zebra. It doesn't mean you're gonna see

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it every.

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Speaker 3: Day, but it's not something And oh my god, you know,

319
00:15:44,759 --> 00:15:46,759
I got to call a Guinness Book a World Records

320
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here because I got a case of cushings. So we

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are talking about the testing. First of all, you have

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the clinical disease, clinical disease. Once again, you have the

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dog typically that's drinking water like crazy, therefore peeing like crazy.

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Their skin is very thin. It's they have a bloated

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belly appearance, sometimes a sway back. They're losing a little

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bit of muscle tone, some hair loss, and we call

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it endocrine alopecian. The reason why we say endocrine is

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because usually the endocrine alopecies alopecia meaning hair loss, they

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are more symmetrical and they're not associated with scratching. So

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if you look at the skin itself, it's you don't

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see scabs and sores things like you would typically see

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with allergic condition.

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Speaker 2: And if you're sort of like.

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Speaker 3: You know, if you were to mentally don't do this

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at home, folks, But if you are mentally going to

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chop the body in half along the longitudinal access the

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right side will look almost exactly the left side like

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mirror image. That's what we call bilaterally symmetrical. And that's

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what we see with these kinds of alopeches with our

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endocrine diseases. If they are going to be endocrine and alopeches,

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so testing so we have a we get a good history.

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And the first thing, of course we're going to do

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is do a basic blood test. And one of the

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things that we pretty much often see when we do

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our basic blood tests is going to be an elevated

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alkaline phosphatase. Now, the ALKN phosphatase is one of the

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four major liver enzymes that we often look at, and

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we know that dogs that are on certain medications like

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corticosteroids also like phenobarbitol, but like steroids, when that dog

350
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is on chronic pregnosoon for some reason, or prenis alone

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or dexamethosone or you name it, they're going to have

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an elevated alkalin phosphatase. Well, when we have a dog

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with cushings, where in essence, the body is giving itself

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too much cortisome, we're going to see an elevated alkan phosphatase.

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Then I mean elevated like high normal is like one

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00:17:32,640 --> 00:17:34,279
hundred to one hundred and thirty, depending on the lab

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00:17:34,279 --> 00:17:37,720
you're gonna use. We're talking dogs that present with values

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00:17:37,839 --> 00:17:40,599
over one thousand, eight hundred. I had a dog as

359
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high as twenty five hundred, I mean three thousand.

360
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Speaker 2: It's ridiculously high.

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Speaker 3: So given the presentation, the PUPD, the skin changes, those

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00:17:48,960 --> 00:17:53,279
sway back, all that stuff, and an elevated alkalin phosphatase

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that is highly suggestive. Note that we did not say

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it's diagnostic. These are things that are highly suggested. And

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00:18:01,000 --> 00:18:03,359
the reason I say that is we've had dogs that

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present a typically where they have all the PPD, the

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00:18:07,039 --> 00:18:09,599
drinking and the peeing, they have their skin the body changes,

368
00:18:09,720 --> 00:18:12,200
but their alkaline phosphase is totally normal. Are you going

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00:18:12,240 --> 00:18:14,160
to stop there and say no, it's not cushings, Of

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course not. It just means that one major test, that

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00:18:17,240 --> 00:18:20,559
major clue isn't there. So that outcomes one of the

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00:18:20,599 --> 00:18:23,160
real tests that we do to determine the drug ivan

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00:18:23,240 --> 00:18:25,839
determine the disease, and that is called wether one of

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00:18:25,839 --> 00:18:27,960
two back in the day, and it's still used. Nothing

375
00:18:27,960 --> 00:18:31,160
wrong with using it is called the a ctight response

376
00:18:31,200 --> 00:18:34,480
test the adreno cordicotropic hormone response test.

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00:18:34,759 --> 00:18:37,240
Speaker 2: How does this work? Well, this is basically the following.

378
00:18:37,559 --> 00:18:41,559
Speaker 3: We know that a dog that is going to have

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00:18:41,640 --> 00:18:44,599
a stimulation of the adrenal is going to have a

380
00:18:44,640 --> 00:18:49,839
normal increase in its output of the hormone. So basically,

381
00:18:49,960 --> 00:18:52,480
the ACTS typically comes from the pituitary gland in the

382
00:18:52,519 --> 00:18:56,000
brain signaling the adrenal gland to fire and it releases

383
00:18:56,119 --> 00:18:59,920
it's hormone, it's cortisol. But dogs with cushings, as I said,

384
00:19:00,279 --> 00:19:03,720
they don't look at your normal type of release of

385
00:19:03,759 --> 00:19:08,000
the cortisol from the adrenal gland. They go gangbusters. So

386
00:19:08,160 --> 00:19:10,279
we know what the normal dog does. So what the

387
00:19:10,279 --> 00:19:13,200
actate response test does is we give a certain measured

388
00:19:13,200 --> 00:19:16,319
amount of the corticotropic hormone and then depending on what

389
00:19:16,319 --> 00:19:18,200
we use in which technique we use, whether it's given

390
00:19:18,200 --> 00:19:20,119
IVY or I AM, but once to two hours later,

391
00:19:20,240 --> 00:19:23,039
we then go ahead and remeasure the cortisol level of

392
00:19:23,039 --> 00:19:25,720
the blood and if it is off the charts high,

393
00:19:25,960 --> 00:19:29,039
then we assume cushings. Another test that seems to be

394
00:19:29,039 --> 00:19:31,039
a little bit more in vogue now is called the

395
00:19:31,279 --> 00:19:35,880
low dose dexmethisone suppression test. As I also mentioned, typically

396
00:19:36,279 --> 00:19:39,920
dogs respond is like a feedback mechanism continually going on

397
00:19:40,160 --> 00:19:42,759
between the petutary land, the bloodstream, the amount of cordothol

398
00:19:42,799 --> 00:19:45,599
the blood stream, and the firing of the adrenal gland.

399
00:19:45,880 --> 00:19:49,319
So what happens is if we give the body a

400
00:19:49,440 --> 00:19:53,119
measured amount of cortisome in the form of dex methisome,

401
00:19:53,480 --> 00:19:57,440
then the normal dog, sensing and seeing the body has

402
00:19:57,559 --> 00:20:01,480
plenty of cortisol on board, will shut down and stop secreting,

403
00:20:01,680 --> 00:20:04,599
and therefore the adrenal gland will not secrete anymore of

404
00:20:04,599 --> 00:20:07,759
its own cortosol. Basically the pituitary and the adrenal combined,

405
00:20:07,799 --> 00:20:11,440
whichever whether it's your cushions disease crushing syndrome, is basically saying, hey,

406
00:20:11,680 --> 00:20:13,759
we got enough, we don't have to work, sit back

407
00:20:13,799 --> 00:20:16,440
and relax, but dogs with cushions don't.

408
00:20:16,880 --> 00:20:20,200
Speaker 2: So what we do is, even though we're suppressing.

409
00:20:20,000 --> 00:20:24,640
Speaker 3: With the decimethisoone, we are still seeing firing and based

410
00:20:24,680 --> 00:20:28,519
on some calculations and measurements, this test, it's a blood

411
00:20:28,519 --> 00:20:31,599
test taken. We inject the steroid, we take a follow

412
00:20:31,680 --> 00:20:34,039
up at four hours and at eight hours and then

413
00:20:34,319 --> 00:20:37,480
at eight hours they depending on the levels, you can

414
00:20:37,559 --> 00:20:40,039
determine that whether the problem is coming from the actual

415
00:20:40,200 --> 00:20:44,759
adrenal land meaning Cushing's disease or to the pituitary land

416
00:20:45,000 --> 00:20:47,759
meaning Cushing's syndrome. So that's why a lot of the

417
00:20:47,759 --> 00:20:49,759
internet is like it because it helps us. And then

418
00:20:49,799 --> 00:20:52,160
of course, if we really want to try to suppress,

419
00:20:52,400 --> 00:20:55,920
then you go in and do a high dose dexamethisone

420
00:20:55,920 --> 00:20:59,119
suppression test with a high dose basically of the normal.

421
00:20:59,240 --> 00:21:01,880
If it's a normal suitary problem, it's going to suppress

422
00:21:02,039 --> 00:21:04,440
and then we'll know if it's still not listening to us,

423
00:21:04,640 --> 00:21:08,519
most likely then we have a adrenal problem. So if

424
00:21:08,559 --> 00:21:12,559
those tests are abnormal, then we and have a suspicion.

425
00:21:12,920 --> 00:21:14,839
We can do the next step, and that is well

426
00:21:15,079 --> 00:21:18,680
to really confirm, let's go to the ultrasound machine. And

427
00:21:18,720 --> 00:21:20,640
with the ultrasam machine again in the hands, a lot

428
00:21:20,640 --> 00:21:23,440
of general practitioners may not have the skill or the

429
00:21:23,559 --> 00:21:26,920
quality of ultrasound machine to actually make this determination, but

430
00:21:27,039 --> 00:21:29,319
certainly the intern is do and that is let's go

431
00:21:29,400 --> 00:21:33,519
ahead and check out the adrenal gland at the kidney

432
00:21:33,680 --> 00:21:35,599
through the ultrasound and see doesn't look huge.

433
00:21:35,720 --> 00:21:36,680
Speaker 2: So if the.

434
00:21:36,680 --> 00:21:39,559
Speaker 3: Assumption is everything checks out that we have cushions disease,

435
00:21:39,839 --> 00:21:42,559
now it's time to treat, and the treatment options are

436
00:21:42,839 --> 00:21:44,680
quite a few. There is a drug that we all

437
00:21:44,759 --> 00:21:47,640
used to use years ago called lycodron. The chemical name

438
00:21:47,720 --> 00:21:50,359
was either might attain or OPDDD, and that was a

439
00:21:50,480 --> 00:21:54,839
drug that would actually suppress the adrenal gland. It would

440
00:21:54,839 --> 00:21:58,599
actually eat the adrenal gland up, and in fact one treatment.

441
00:21:58,640 --> 00:21:59,960
In Europe, what they do is they used to give

442
00:22:00,119 --> 00:22:02,960
the opdd so much that they used to obliterate the

443
00:22:03,119 --> 00:22:06,400
entire gland and then treat the dog as an Addisonian,

444
00:22:06,440 --> 00:22:08,400
which is the disease we're going to talk about next week,

445
00:22:08,440 --> 00:22:12,079
which is an under secretion of the adrenal gland. That's

446
00:22:12,079 --> 00:22:15,880
Addison's disease, and Addison's disease. Dogs are pretty are actually

447
00:22:16,000 --> 00:22:18,480
much easier to treat. So in some places in Europe,

448
00:22:18,480 --> 00:22:20,920
I think in Sweden, their treatment of bushings is to

449
00:22:21,240 --> 00:22:23,039
let's make them into an Adisonian and treat We.

450
00:22:23,119 --> 00:22:23,720
Speaker 2: Never did that here.

451
00:22:23,759 --> 00:22:27,079
Speaker 3: We tried to tighter exactly tight trade I should say

452
00:22:27,319 --> 00:22:28,119
how much.

453
00:22:28,000 --> 00:22:29,279
Speaker 2: OPDDD could be given.

454
00:22:29,400 --> 00:22:32,960
Speaker 3: There's a newer drug called Trilastain was first used in

455
00:22:33,000 --> 00:22:36,200
Canada a lot now under the trade name Veteral that

456
00:22:36,319 --> 00:22:38,920
most of us are using, and that is again measured

457
00:22:38,920 --> 00:22:43,359
by weight, and its goal is to again decrease the

458
00:22:43,400 --> 00:22:47,440
amount of output put out by the adrenal gland and

459
00:22:47,799 --> 00:22:50,720
thus monitor these dogs via the actate response test. So

460
00:22:50,880 --> 00:22:53,880
even if we made the diagnosis originally using the low

461
00:22:53,920 --> 00:22:58,359
dose dex methosone suppression test, we monitor our success on

462
00:22:58,400 --> 00:23:02,400
the veteral using the act response tests, and that drug

463
00:23:02,559 --> 00:23:03,240
is very safe.

464
00:23:03,319 --> 00:23:04,720
Speaker 2: Dogs do very well on it.

465
00:23:05,039 --> 00:23:08,759
Speaker 3: And of course if we have confirmation via our testing

466
00:23:08,880 --> 00:23:11,799
and our ultrasound that our problem is most likely the

467
00:23:11,839 --> 00:23:15,079
adrenal tumor itself, then of course in the hands of

468
00:23:15,119 --> 00:23:18,319
a qualified surgeon, that adrenal gland or the adrenal glands

469
00:23:18,480 --> 00:23:20,960
can be removed. And then again we're going to have

470
00:23:21,000 --> 00:23:24,039
an Adisonian and then we treat accordingly as we would

471
00:23:24,119 --> 00:23:27,079
in Addison's which we're going to cover next week. So

472
00:23:27,319 --> 00:23:31,319
the options are many. These dogs can live somewhat normally.

473
00:23:31,400 --> 00:23:34,119
We do see some complications, however, in that many of

474
00:23:34,119 --> 00:23:36,920
these not many. Some dogs that have it cushions might

475
00:23:36,920 --> 00:23:39,480
also have diabetes going on at the same time, it's

476
00:23:39,480 --> 00:23:41,599
a disease we're going to cover in a few weeks

477
00:23:41,920 --> 00:23:45,160
that diabetes melodis. Now we get complicated because it's almost

478
00:23:45,160 --> 00:23:48,759
like the treatments are opposing each other because the anti

479
00:23:48,799 --> 00:23:52,440
insulin effect of high dose steroids. And then we really said,

480
00:23:52,440 --> 00:23:54,279
now we're giving you know, we have a disease that

481
00:23:54,440 --> 00:23:57,480
is secreting too much steroid. We get this anti insulin

482
00:23:57,480 --> 00:23:59,519
effect because of the steroid. That's where it gets very,

483
00:23:59,599 --> 00:24:02,599
very comp and these dogs are a lot more difficult

484
00:24:02,799 --> 00:24:05,400
to adjust, but it can be done. I'm in the

485
00:24:05,400 --> 00:24:07,440
midst of treating one right now. We've been you know,

486
00:24:07,519 --> 00:24:09,559
kind of going on for a while ago Lucy who

487
00:24:09,559 --> 00:24:13,880
has both diabetes and cushings just to throw us a

488
00:24:13,920 --> 00:24:16,119
hell of a curve when it comes to treating these

489
00:24:16,200 --> 00:24:20,960
endocrine disorders. So again, to recap cushing disease, it's a

490
00:24:21,000 --> 00:24:24,119
drenal and or pituitary problem. It's an over secretion and

491
00:24:24,160 --> 00:24:26,920
the body is presenting too much cortisol. The changes in

492
00:24:26,960 --> 00:24:30,319
the blood will usually dictate that. Behavior changes will dictate

493
00:24:30,359 --> 00:24:32,759
that the skin how these dogs present and look, we'll

494
00:24:32,799 --> 00:24:37,000
dictate that. And so our job is to minimize that

495
00:24:37,039 --> 00:24:40,200
secretion to regulate it as best we can. We have

496
00:24:40,240 --> 00:24:42,720
a number of drugs or surgery available to us, but

497
00:24:43,079 --> 00:24:46,400
don't fret because it is a condition that we can

498
00:24:46,720 --> 00:24:50,279
and often do, work with. So if you have any

499
00:24:50,400 --> 00:24:54,039
questions about Cushing's disease, Cushing syndrome, if you have a

500
00:24:54,079 --> 00:24:56,920
dog who's being treated or has been treated, or you've

501
00:24:56,920 --> 00:24:58,759
had a dog in the past, we would love to

502
00:24:58,759 --> 00:25:00,720
hear from you, find out how how it went. Get

503
00:25:00,759 --> 00:25:04,960
your input because other listeners are going to learn from you,

504
00:25:05,440 --> 00:25:07,400
just like taking learn from me, because you've been there,

505
00:25:07,480 --> 00:25:09,640
done that. Here, I am been treating this for years.

506
00:25:09,680 --> 00:25:12,640
I've never, in all my years of being a pet

507
00:25:12,720 --> 00:25:16,200
dad a dog dad, have had a dog with Cushion's

508
00:25:16,200 --> 00:25:19,000
disease or diabetes. For that fact, I shouldn't jinx myself.

509
00:25:19,039 --> 00:25:21,720
But so we want to hear from you to see

510
00:25:21,759 --> 00:25:24,319
how things are going for you. How is it working out,

511
00:25:24,480 --> 00:25:27,000
Are you happy that you're treating? Do you have any

512
00:25:27,000 --> 00:25:29,039
doubts that maybe you shouldn't have? This is what we

513
00:25:29,079 --> 00:25:30,359
want to know. So I want you to give us

514
00:25:30,359 --> 00:25:32,240
a call next week or send me an email and

515
00:25:32,279 --> 00:25:34,880
I'll share it on air. To Drgeff at Petlife Radio

516
00:25:34,960 --> 00:25:36,880
dot com or you can give us a call next week.

517
00:25:36,920 --> 00:25:38,160
We'd love to hear from you as we're going to

518
00:25:38,160 --> 00:25:41,359
be talking about Addison's disease, which is the opposite the

519
00:25:41,480 --> 00:25:45,240
under secretion of the adreno gland. And you can give

520
00:25:45,319 --> 00:25:47,480
us a call at eight seven seven three eight five

521
00:25:47,680 --> 00:25:50,200
eight eight eight two. Thanks for joining us here. I'm

522
00:25:50,200 --> 00:25:52,799
your host, doctor Jeff Werber. Thanks again to our sponsors

523
00:25:52,799 --> 00:25:55,440
Pro Sense and Kong, and we will see you here

524
00:25:55,759 --> 00:25:56,480
next Sunday.

525
00:25:56,880 --> 00:26:01,440
Speaker 1: Let's Talk Pets every week on demand only on petlight

526
00:26:01,599 --> 00:26:16,880
radio dot com.

