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<v Speaker 1>Oh hey, it's the bowl that's chipped, but not chipped

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<v Speaker 1>enough to throw it away. Ali Ward, this is ologies,

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<v Speaker 1>this is OCD. Okay. We asked y'all on Patreon your

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<v Speaker 1>most desired episodes, and this was among the top, which

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<v Speaker 1>was both a surprise. It was also a delight to me.

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<v Speaker 1>Also a delight we got the world's most revered expert

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<v Speaker 1>in OCD to talk to me for an hour. This

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<v Speaker 1>person invented this scale by which OCD is measured. They've

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<v Speaker 1>been working in this field for many, many decades and

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<v Speaker 1>is pioneering a bunch of new treatment and research for it.

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<v Speaker 1>They studied at Boston University and Yale School of Medicine.

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<v Speaker 1>They've also been instrumental in nonprofit work for OCD treatment

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<v Speaker 1>and research. They're now a professor and the chair at

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<v Speaker 1>the manager Department of Psychiatry and Behavioral Sciences at Baylor

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<v Speaker 1>College in Houston. And if you have OCD, or you

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<v Speaker 1>know someone who does or might, their life is better

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<v Speaker 1>because of this absolute OCD icon And just a content note,

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<v Speaker 1>of course, we talk about some parts of OCD that

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<v Speaker 1>are distressing to people, and that's part of why we're

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<v Speaker 1>doing this to talk about it. But just to content

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<v Speaker 1>warning up top that we do touch on self harm

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<v Speaker 1>and some intrusive thoughts that might be a little disturbing

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<v Speaker 1>to people. Now. I was nervous as hell to hop

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<v Speaker 1>on this interview because I know their time is very limited,

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<v Speaker 1>but we were able to cover so much, including questions

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<v Speaker 1>from patrons at patreon dot com slash ologies, you also

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<v Speaker 1>can ask questions before we record. You can join that

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<v Speaker 1>for less than twenty five cents an episode. Also, Ologies

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<v Speaker 1>Merch is available at ologiesmerch dot com should you need it,

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<v Speaker 1>and for no dollars. You can support the show just

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<v Speaker 1>by leaving a review and I read them all and

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<v Speaker 1>then I pick freshy to read, such as this one

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<v Speaker 1>this week from Mishar, who wrote, if you were a

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<v Speaker 1>kid who went to these Scholastic book fairs looking for

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<v Speaker 1>nonfiction books or fun facts books, this is the podcast

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<v Speaker 1>for you, Meshar. Let's crack into the catalog. Let's get

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<v Speaker 1>some mo CD but verse. Also thanks to sponsors of

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<v Speaker 1>the show for making it possible to donate to a

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<v Speaker 1>Okay is OCD a niche condition. I would have thought so,

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<v Speaker 1>since people don't talk about it a lot unless it's

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<v Speaker 1>an offhand punchline or like an excuse for a complicated

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<v Speaker 1>Starbucks order. But research reveals that OCD is now considered

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<v Speaker 1>one of the most common psychiatric conditions, afflicting two to

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<v Speaker 1>three percent of the general population. I did not know that.

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<v Speaker 1>And because of the high demand for this episode, and

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<v Speaker 1>because it's so close to my heart, surprise, we have

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<v Speaker 1>a bonus episode coming out in a few days. We've

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<v Speaker 1>been cooking up. It's all about lived experience. It's with

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<v Speaker 1>a lovely neuroscientist, researcher, board certified mental health peer specialist,

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<v Speaker 1>and mental health advocate UMA Chatterjy so Yes an extra

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<v Speaker 1>episode this week. Enjoy. That's a great conversation. But for now,

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<v Speaker 1>let's take a deep breath. Let's treat our brains to

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<v Speaker 1>a feast of info on overt versus covert, perfectionism, obsessions

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<v Speaker 1>versus compulsions, neurodivergence and OCD, pediatric illness induced OCD symptoms, ruminations, checking, counting, reassurance, seeking,

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<v Speaker 1>a few famous folks who are helping break stigmas, medicines

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<v Speaker 1>on the forefront some hopeful treatments in the future, finding

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<v Speaker 1>a therapist, deep brain stimulation, genetic components overlap with trust syndrome,

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<v Speaker 1>advice for loved ones, and the behavioral therapy that is

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<v Speaker 1>the gold standard for OCD. With doctor, psychiatrist, researcher, advocate,

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<v Speaker 1>and OCD neurobiologist, the doctor Wayne Goodman.

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<v Speaker 4>I'm Wayne Goodman, he him. I'm a psychiatrist and I

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<v Speaker 4>work at the Balacology of Medicine down in Houston, Texas.

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<v Speaker 1>Really excited to talk to you. We've wanted to do

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<v Speaker 1>this episode for literally years, and everyone we've talked to

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<v Speaker 1>has said you are a perfect choice for this, so

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<v Speaker 1>we're very excited to be speaking to you. Specifically, hundreds

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<v Speaker 1>of papers last I saw on research Gate thirty six

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<v Speaker 1>thousand citations to your work. I believe you started in

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<v Speaker 1>the eighties.

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<v Speaker 4>Yes, it's hard to believe. It was the nineteen eighty five,

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<v Speaker 4>so forty years.

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<v Speaker 1>Forty years. What got you started down this path?

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<v Speaker 4>So I was at Yale doing my residency and starting

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<v Speaker 4>a research fellowship, and I came across a patient with OCD,

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<v Speaker 4>and it was the first patient I had seen with OCD,

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<v Speaker 4>and started reading about it and I began to realize

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<v Speaker 4>it wasn't that much known, particularly about the neurobiology or

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<v Speaker 4>the treatment. So long story short, wound up launching the

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<v Speaker 4>OCD program at Yale, and I've been focusing on OCD

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<v Speaker 4>ever since.

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<v Speaker 1>Was there something about this patient? Was it the level

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<v Speaker 1>of suffering or the level of OCD that really hooked you?

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<v Speaker 1>Were they particularly nice? Were they a patient you liked?

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<v Speaker 4>Were he well, I like all my patients. But of

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<v Speaker 4>course this patient had kind of a classic form of

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<v Speaker 4>OCD involving contamination concerns and fear that if they didn't

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<v Speaker 4>wash their hands carefully they would get somebody else sick,

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<v Speaker 4>particularly somebody they loved. And they realized that whatever they

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<v Speaker 4>were doing, whatever they were thinking about, was excessive. So

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<v Speaker 4>that's what really struck me. You know, that this person

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<v Speaker 4>was driven to the point that she used to have

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<v Speaker 4>to use bleach on our hands. Her hands were red bleach,

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<v Speaker 4>I mean it could be caustic because not only skin irritation,

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<v Speaker 4>but actual damage. And she was consumed by these thoughts

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<v Speaker 4>almost every hour the waking day. But yet again, she

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<v Speaker 4>had complete insight into how absurd it was. And that's

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<v Speaker 4>what struck me was that paradox between the irrationality of

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<v Speaker 4>the thoughts, the excessiveness of the behaviors, and totally preserved

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<v Speaker 4>insight and executive functioning.

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<v Speaker 1>So this is a classic presentation of OCD and it's

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<v Speaker 1>probably what people think of first because it's just easy

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<v Speaker 1>to explain too. And according to the research, up to

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<v Speaker 1>forty six percent of folks with OCD do deal with

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<v Speaker 1>contamination fears, but the other fifty four percent, the majority,

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<v Speaker 1>don't struggle with that. And at that time, were there

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<v Speaker 1>scales to measure this? Was it something that was being

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<v Speaker 1>treated with medicine? I know, the Yale Brown Obsessive Compulsive

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<v Speaker 1>Scale is something that you pioneered, which among people who

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<v Speaker 1>know OCD, they're like, WHOA that dud? Did the actual

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<v Speaker 1>test OG? So the Yale Brown Obsessive Compulsive Scale, or

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<v Speaker 1>y box as it's known, is a clinician administered ten

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<v Speaker 1>items scale with each item rated from zero for no

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<v Speaker 1>symptoms to four for extreme symptoms. So scores can run

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<v Speaker 1>zero to forty. And it was developed in nineteen eighty

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<v Speaker 1>nine by a Yale doctor and this OCD legend named

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<v Speaker 1>Wayne Goodman, who we are talking to right now. What

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<v Speaker 1>interventions are, what qualitative analysis was it back then.

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<v Speaker 4>So at the time there were only case reports that

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<v Speaker 4>one medication in particular was effective. It was a medication

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<v Speaker 4>called clomipramine, which is still available, and it was one

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<v Speaker 4>of the older medications with lots of side effects, and

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<v Speaker 4>the case report suggested it was the only medication that

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<v Speaker 4>seemed to work, and there was a theory that the

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<v Speaker 4>reason it worked is because it had potent effects on

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<v Speaker 4>the brain's serotonin system. Serotonin is one of the brain's

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<v Speaker 4>neurotransmitters or neurochemicals, and my training at Yale really focused

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<v Speaker 4>on trying to understand not only treatment but neurobiology. So

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<v Speaker 4>that led me to want to test a newer generation

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<v Speaker 4>of medications that were selective for their effects and serotonin.

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<v Speaker 4>And then I looked around and back to your question

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<v Speaker 4>about rating scales, there really weren't any gold standard scales.

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<v Speaker 4>So I work with my colleagues on developing one.

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<v Speaker 1>Is that something that a person can administer themselves or

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<v Speaker 1>is that really something that you got to talk through

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<v Speaker 1>with a doctor who can figure out, you know, very impacted,

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<v Speaker 1>somewhat impacted. Can people self diagnosed OCDA? Yes?

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<v Speaker 4>So the way the y box, that's the Yale Brown

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<v Speaker 4>Obsessive Compulsive scale is administered, is it should be by

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<v Speaker 4>a clinician who has experience in treating OCDA. There are

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<v Speaker 4>forms of the scale that are self rated so that

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<v Speaker 4>the patient fills them out, but really the diagnosis is

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<v Speaker 4>left up to the clinician.

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<v Speaker 1>We hear so often and I'm wondering how you feel

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<v Speaker 1>about this when people say I'm so OCDA, Like I

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<v Speaker 1>love to have all my pens in the same spot

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<v Speaker 1>on my desk. People with OCD, from what I understand,

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<v Speaker 1>hate that a lot.

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<v Speaker 4>Yeah they do.

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<v Speaker 1>Yeah, how do you feel as a professional and a

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<v Speaker 1>clinician when you hear people say I'm so OCDA.

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<v Speaker 4>Well, you know, I'm not judgmental. That's one of the

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<v Speaker 4>good things that you need to be as a psychiatrist.

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<v Speaker 4>But I do point out that that's not the same

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<v Speaker 4>as OCD.

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<v Speaker 1>Doctor Goodman says it's healthy and common to have certain

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<v Speaker 1>preferences or routines.

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<v Speaker 4>Sure, meaning being perfectionist, liking things orderly. Those are good,

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<v Speaker 4>but it's not a disorder until it takes up a

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<v Speaker 4>lot of time and by definition would be more than

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<v Speaker 4>an hour a day. It would be distressing and for

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<v Speaker 4>most of the patients. I treat and I focus on

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<v Speaker 4>treatment resistant OCD. I focus on severe OCD. We're talking

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<v Speaker 4>about patients that can't go sometimes fifteen minutes without having

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<v Speaker 4>an intrusive thought or having to perform a compulsion.

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<v Speaker 1>Well to find those in a moment, and our Surprise

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<v Speaker 1>Owners episode out later this week with Uma goes into

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<v Speaker 1>a ton of detail about lived experience.

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<v Speaker 4>So that's very different from the people who are you know,

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<v Speaker 4>have a little bit of OCD in them, like things

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<v Speaker 4>orderly and are still able to work and lead a

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<v Speaker 4>very productive life. People with very severe OCD can be incapacitated.

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<v Speaker 4>Although many of my patients, despite their severe symptoms of

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<v Speaker 4>figure out ways of still working around them, and a

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<v Speaker 4>lot of patients. The other thing about patients with OCD

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<v Speaker 4>is they're really good at camouflaging their symptoms.

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<v Speaker 1>Now we'll get to kind of outward behavior versus inward,

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<v Speaker 1>but you mentioned severe versus kind of high functioning or

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<v Speaker 1>people who can function around it. Well, is it a

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<v Speaker 1>spectrum like a lot of other conditions.

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<v Speaker 4>Yeah. Yeah, So even on the Y box, the rating

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<v Speaker 4>scale goes from zero to flority, and most patients that

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<v Speaker 4>we treat in an outpaidation setting of first line treatments

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<v Speaker 4>they discore around twenty, you know, like the midpoint, and

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<v Speaker 4>those patients can continue to work, go to school, lead

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<v Speaker 4>a very productive life. But the OCD is kind of

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<v Speaker 4>annoying at them and interfering with their ability to be

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<v Speaker 4>fully functional and fulfilling life.

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<v Speaker 1>One thing that really surprised me about OCD is that

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<v Speaker 1>it's not the same as an anxiety disorder. It's not

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<v Speaker 1>underneath the umbrella of anxiety disorders. Is that correct?

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<v Speaker 4>That's correct as of the DSM five, the Diagnostic Statistical Manual,

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<v Speaker 4>fifth edition that came out in twenty thirteen. Before that,

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<v Speaker 4>it was considered an anxiety disorder, and actually I'm not

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<v Speaker 4>sure it was the right decision not to call it

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<v Speaker 4>an anxiety disorder. It's now listed in this DSM five

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<v Speaker 4>manual as in the obsessive, compulsive and related disorders. But

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<v Speaker 4>anxiety is almost always a component of OCD.

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<v Speaker 1>Does the anxiety tend to come from trying to control

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<v Speaker 1>the OCD? Like people who have ADHD might have a

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<v Speaker 1>lot of anxiety because executive function is difficult for them.

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<v Speaker 1>Is the anxiety sometimes a byproduct?

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<v Speaker 4>It comes in various forms, but OCD comes in various flavors.

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<v Speaker 4>But all patients with OCD by definition have obsessions and compulsions,

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<v Speaker 4>and the obsessions are the intrusive thoughts or images, and

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<v Speaker 4>those by themselves are distressing kind of by definition, an

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<v Speaker 4>obsession is something that is disturbing.

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<v Speaker 1>More on these in a sec and in the bonus

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<v Speaker 1>episode with uma. But these can again be the fear

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<v Speaker 1>of getting sick and getting someone else sick, existential OCD

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<v Speaker 1>about whether you really exist. There's a false memory OCD,

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<v Speaker 1>perfectionism OCD relating to order and symmetry and counting that

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<v Speaker 1>just feel off if incorrect. It's also harm OCD worrying

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<v Speaker 1>that you might impulsively hurt yourself or others on accident

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<v Speaker 1>or on purpose. And a very seldom discussed facet of

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<v Speaker 1>OCD is pedophilia OCD. And this is a distressing worry

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<v Speaker 1>that you will harm a child. But wait, there's more.

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<v Speaker 1>There's moral scrupulosity, worrying about if you're a bad person

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<v Speaker 1>who doesn't know it. There's checking OCD like with matters

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<v Speaker 1>of safety like ovens or curling irons or locks, and

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<v Speaker 1>there's reassurance seeking OCD. All of these obsessions can run

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<v Speaker 1>like a ticker tape in your brain, and you would

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<v Speaker 1>really like them to shut up. How do you do that? Compulsions?

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<v Speaker 4>And then the compulsions are designed in a way to

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<v Speaker 4>reduce the anxiety associated with that obsession. But sometimes the

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<v Speaker 4>compulsions themselves can be so time consuming, so like the

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<v Speaker 4>patient I mentioned before, you know, or even painful. I've

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<v Speaker 4>had patients who took a shower so long that they

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<v Speaker 4>ran out of hot water and they wound up taking

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<v Speaker 4>the cold shower until they feel that they're clean enough.

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<v Speaker 1>You mentioned your one of your first patients had contamination OCD,

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<v Speaker 1>but I understand there's a lot of flavors. As you mentioned,

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<v Speaker 1>there's pure OCD, there's moral scrupulosity, there's checking OCD numbers,

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<v Speaker 1>there's reassurance seeking. So there's a lot of different ways

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<v Speaker 1>that the obsessions and compulsions show up. Can you talk

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<v Speaker 1>a little bit about pure OCD versus contamination versus moral.

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<v Speaker 4>Well, yeah, so again going back to the Y box,

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<v Speaker 4>we had this first part where we do the symptom checklist,

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<v Speaker 4>and when I worked out that with my colleagues, we

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<v Speaker 4>saw hundreds of patients together and came up with a

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<v Speaker 4>list of different categories. So different categories of obsessions include contamination,

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<v Speaker 4>but also, like you mentioned, scrupulosity is a big one.

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<v Speaker 4>It could be about taboo thoughts about religion or sexuality,

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<v Speaker 4>unwanted aggressive thoughts, you know, fear that you would be

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<v Speaker 4>responsible for harming somebody or harming yourself even though you

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<v Speaker 4>don't want to. And there's a whole bunch of miscellaneous

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<v Speaker 4>ones that can occur as well.

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<v Speaker 1>So in response to those thoughts.

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<v Speaker 4>And the compulsions are generally designed. Again, design is probably

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<v Speaker 4>not the right word, but they're functionally connected to the

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<v Speaker 4>obsessions that try to reduce them, and they're not always

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<v Speaker 4>in the form of something like washing or contamination that

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<v Speaker 4>you can observe. They can be if say, somebody has

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<v Speaker 4>an intrusive thought of something terrible happening to a loved one.

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<v Speaker 4>They could recite something in their head, or they can

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<v Speaker 4>review something in their head and you can't see that,

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<v Speaker 4>but we would count that as a compulsion as well.

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<v Speaker 1>And via the paper Prevalence and Clinical Characteristics of Mental

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<v Speaker 1>Rituals and Longitudinal Clinical Sample of Obsessive Compulsive Disorder in

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<v Speaker 1>the Journal Depression Anxiety, there are overt and physical, which

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<v Speaker 1>you're probably more familiar with, but there are also covert

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<v Speaker 1>or mental compulsions with no behavioral signs, and those types

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<v Speaker 1>of compulsions include acts like silently repeating words or phrases,

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<v Speaker 1>or praying or counting, or mental checking or thinking of

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<v Speaker 1>good or safe thoughts to neutralize distressing mental images, among others. Now,

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<v Speaker 1>that has to be a slim majority, right, that has

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<v Speaker 1>the covert kind right. Nope. So this paper cites research

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<v Speaker 1>suggesting that as many of sixty percent of OCD patients

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<v Speaker 1>present without overt compulsions, meaning the majority of folks with

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<v Speaker 1>OCD may just be struggling internally with mental compulsions, trying

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<v Speaker 1>to undo the obsessive thoughts with other thoughts.

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<v Speaker 4>Now you mentioned about pure obsessions. Yeah, there was a

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<v Speaker 4>country star talking about did you see this about the

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<v Speaker 4>pure ocday? Oh? Okay, Oh I want met the name,

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<v Speaker 4>but you can look it up.

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<v Speaker 1>Okay. It's Luke Comb's and he's been super public about it,

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<v Speaker 1>and an article in NBC News reported that Combs hopes

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<v Speaker 1>to use his platform to support others facing similar struggles,

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<v Speaker 1>and in a recent interview with sixty Minutes Australia, Luke

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<v Speaker 1>Combs explained his experience that it's thoughts essentially that you

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<v Speaker 1>don't want to have, and then they cause you stress,

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<v Speaker 1>and then you're stressed out, and then the stress causes

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<v Speaker 1>you to have more of the thoughts, and then you

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<v Speaker 1>don't understand why you're having them, and you're trying to

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<v Speaker 1>get rid of them, but trying to get rid of

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<v Speaker 1>them makes you have more of them. So what is

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<v Speaker 1>pure O? Just obsessions?

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<v Speaker 4>And said that he had the form of pure OCD.

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<v Speaker 4>It's a controversial entity. Most of us in the field

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<v Speaker 4>who have seen a lot of OCD can identify mental

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<v Speaker 4>rituals that patients perform when they have their intrusive thoughts.

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<v Speaker 4>So I don't think pure oc Well, pure O is

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<v Speaker 4>actually that common. I think most patients who have really

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<v Speaker 4>a real case of O and they may not perform

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<v Speaker 4>overt rituals, but they're probably doing something mentally to try

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<v Speaker 4>to ameliorate the anxiety associated with their thoughts or their images.

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<v Speaker 1>Oh got it. So pure O is just the obsessions,

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<v Speaker 1>is what they're saying without compulsion.

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<v Speaker 4>Yes, it's just the obsessions. Yeah, and the vast majority

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<v Speaker 4>of patients with OCD you have both.

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<v Speaker 1>So Goodman is iffy on pure O because again, compulsions

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<v Speaker 1>to stop the obsessions can be covert or mental and

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<v Speaker 1>not outwardly behavioral. But usually yes, the ways that you

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<v Speaker 1>try to stop the obsessions are compulsions. The O and

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<v Speaker 1>the C are the buddy comedy that you never asked for.

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<v Speaker 4>And they seem to be functionally connected.

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<v Speaker 1>So is it possible that some people might not realize

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<v Speaker 1>the compulsions that they're even doing, and they might just think, Oh,

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<v Speaker 1>because I'm not doing something physical, then I don't have

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<v Speaker 1>a compulsion, right.

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<v Speaker 4>They might think they hit pure o, which they probably don't.

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<v Speaker 1>Oh that's interesting, Okay, I wasn't sure about that.

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<v Speaker 4>Yeah.

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<v Speaker 1>Now, what are some of the more overlooked types of

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<v Speaker 1>OCD that you feel like the general public doesn't know

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<v Speaker 1>much about. I feel like the ones I hear about

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<v Speaker 1>a lot are contamination and checking, making sure that the

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<v Speaker 1>curling irons unplugged, that everything's stove is off, that the

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<v Speaker 1>front door is locked. You have difficulty believing that you've

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<v Speaker 1>done those things, and so you have to keep checking.

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<v Speaker 1>But can you elaborate on some of the other, maybe

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<v Speaker 1>more overlooked ones.

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<v Speaker 4>Yeah, there's a category we sometimes refer as just se

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<v Speaker 4>or just write OCD where people have to repeat something

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<v Speaker 4>I have patient recently who was looking at the clock,

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<v Speaker 4>and she really wasn't looking to see what time it was.

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<v Speaker 4>She had superstitious concerns about she had to watch the

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<v Speaker 4>second hand of the clock and see it hit twelve,

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<v Speaker 4>because otherwise she had had this thought if she doesn't

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<v Speaker 4>see the twelve, something bad is going to happen to her.

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<v Speaker 4>And the other things that she would do could be

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<v Speaker 4>really random. She could just repeatedly touch something or repeat

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<v Speaker 4>something and you wouldn't notice it. And I would ask her,

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<v Speaker 4>how do you know when it's done? How do you

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<v Speaker 4>know when you've done enough of these performed enough of

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<v Speaker 4>these compulsions, And she would say, and to it feels

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<v Speaker 4>just right. So it's kind of the just right feeling,

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<v Speaker 4>and people have a hard time articulating that, but that's

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<v Speaker 4>a common form that's often overlooked and just full disclosure.

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<v Speaker 1>I was diagnosed two years ago with OCD. Never realized

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<v Speaker 1>that I had it. I don't have a super severe case,

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<v Speaker 1>but I look back and I'm like, I had some

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<v Speaker 1>stationary that I've had for twenty years, and I was like,

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<v Speaker 1>if I use the last piece of the stationary, my

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<v Speaker 1>dad will die. Things that I didn't tell anyone that

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<v Speaker 1>I that I even thought because it sounded bonkers, but

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<v Speaker 1>I was very afraid that if I use that something

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<v Speaker 1>bad would happen. Or I have terrible procrastination problems. I'm

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<v Speaker 1>really avoidant because I'm always afraid of making a mistake,

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<v Speaker 1>and then it'll lead to my downfall. My career will

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<v Speaker 1>be over if I make one mistake. And so there's

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<v Speaker 1>there's like a certain kind of magical thinking.

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<v Speaker 4>It feels like, yeah, that's a good category too. Yeah,

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<v Speaker 4>magical thinking.

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<v Speaker 1>This feeling that you can maybe control the outcome of

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<v Speaker 1>bad things and avoid them if you do something concrete

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<v Speaker 1>about it.

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<v Speaker 4>Yeah, even though you know it doesn't make any.

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<v Speaker 1>Sense, right, Yeah, it doesn't make any sense.

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<v Speaker 4>But you don't want to take a chance, exactly because

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<v Speaker 4>the stakes are too high. Stakes are high, and the

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<v Speaker 4>OCD is telling you to do it.

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<v Speaker 1>Oh yeah, or not to do it right exactly because

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<v Speaker 1>if it landed on you, you can never forgive yourself.

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<v Speaker 1>But I feel like, you know, when you mentioned the

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<v Speaker 1>contamination OCD with one of your first patients, worried about

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<v Speaker 1>she would hurt someone else. It feels like the avoidance

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<v Speaker 1>of a bad outcome can fuel a lot of obsessions

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<v Speaker 1>and compulsions. Do you find that with a lot of

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<v Speaker 1>your patients.

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<v Speaker 4>Yeah, I think that's a universal. So again, we talked

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<v Speaker 4>about all the kind of different forms of flavors of OCD,

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<v Speaker 4>but I think most of them have in common that

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<v Speaker 4>patients with OCD are harm avoidant. They're worried about some outcome.

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<v Speaker 4>That outcome, you know, could be something happening to themselves

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<v Speaker 4>or their loved ones, you know, failing at work, you know,

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<v Speaker 4>or having their career go up in smoke. And we've

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<v Speaker 4>talked about scrupulosity. It maybe something that's most dear to

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<v Speaker 4>that particular person is the thing that they're going to

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<v Speaker 4>worry about most.

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<v Speaker 1>That makes sense. And what about onset? When do you

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<v Speaker 1>tend to see OCD become apparent enough? Because I'm sure

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<v Speaker 1>a lot of people might have this as kids. I mean,

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<v Speaker 1>don't step on a crack, You'll break your brother's back.

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<v Speaker 4>I was going to mention that one. Yeah, that's that's

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<v Speaker 4>the classic magical thinking one, but you actually do see it.

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<v Speaker 1>Just a side note, this superstition has folkloric origins and

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<v Speaker 1>it was a common and racist rhyme originally, and about

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<v Speaker 1>five percent of adults still avoid cracks in the sidewalk.

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<v Speaker 1>So let's just retire this one forever. Okay, good love that.

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<v Speaker 1>I wonder how much that particular rhyme is responsible. Yeah,

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<v Speaker 1>but what do you think the onset might typically be?

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<v Speaker 4>So about half the cases of OCD have onset in childhood,

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<v Speaker 4>and then there's another large group in early adulthood. So

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<v Speaker 4>I actually I see a lot of people who first

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<v Speaker 4>have onset of OCD after they go off to college.

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<v Speaker 4>Oh so around that age range. It's unusual to see

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<v Speaker 4>onset after age thirty five.

419
00:24:39.839 --> 00:24:44.680
<v Speaker 1>Okay. Have you seen more people seeking treatment after the

420
00:24:44.799 --> 00:24:48.960
<v Speaker 1>COVID pandemic hit with especially with contamination?

421
00:24:50.160 --> 00:24:52.359
<v Speaker 4>You know, it's funny I should know the answers to that.

422
00:24:52.440 --> 00:24:54.200
<v Speaker 4>In fact, I was on a paper that looked at it.

423
00:24:54.599 --> 00:24:57.039
<v Speaker 4>I don't think it's had a huge impact. It just

424
00:24:57.119 --> 00:25:00.039
<v Speaker 4>made it a little bit more confusing. For example, so

425
00:25:00.079 --> 00:25:02.319
<v Speaker 4>I had a patient who I was treating with very

426
00:25:02.359 --> 00:25:07.640
<v Speaker 4>severe OCD during the pandemic, and he used to wear

427
00:25:07.720 --> 00:25:12.160
<v Speaker 4>three layers of gloves and a mask, and once the

428
00:25:12.480 --> 00:25:14.720
<v Speaker 4>COVID struck, he didn't stand out anymore.

429
00:25:15.200 --> 00:25:15.400
<v Speaker 5>Ah.

430
00:25:15.759 --> 00:25:19.079
<v Speaker 4>He Actually he thought that was really really helpful in

431
00:25:19.200 --> 00:25:22.720
<v Speaker 4>a way that it kind of normalized his appearance. Yeah,

432
00:25:23.000 --> 00:25:25.039
<v Speaker 4>but I don't think so. It may have had a

433
00:25:25.160 --> 00:25:28.039
<v Speaker 4>temporary impact, guess. I mean we were all concerned, but

434
00:25:28.119 --> 00:25:30.599
<v Speaker 4>I don't think it really caused that many new cases

435
00:25:30.680 --> 00:25:31.240
<v Speaker 4>of OCD.

436
00:25:31.880 --> 00:25:33.519
<v Speaker 1>And for more on this you can see the twenty

437
00:25:33.599 --> 00:25:37.319
<v Speaker 1>twenty three paper doctor Goodman co authored titled COVID nineteen

438
00:25:37.400 --> 00:25:41.920
<v Speaker 1>Related Intrusive Thoughts and Associated Ritualistic Behaviors, which looked at

439
00:25:42.200 --> 00:25:46.319
<v Speaker 1>a new thing you could have called CRB or COVID

440
00:25:46.480 --> 00:25:53.519
<v Speaker 1>nineteen related Intrusive Thoughts and Associated Ritualistic Behaviors. But the study, however,

441
00:25:53.640 --> 00:25:57.119
<v Speaker 1>concluded that while it's helpful and even critical for providers

442
00:25:57.240 --> 00:26:01.480
<v Speaker 1>to see and take into account COVID related distress, it's

443
00:26:01.680 --> 00:26:04.039
<v Speaker 1>likely a Chicken or the X situation. That is, if

444
00:26:04.079 --> 00:26:09.359
<v Speaker 1>you only noticed obsessive compulsive traits after the COVID pandemic hit,

445
00:26:09.839 --> 00:26:12.000
<v Speaker 1>chances are you already had a little bit of OCD

446
00:26:12.160 --> 00:26:16.759
<v Speaker 1>before then. Also, there is a very baseline preoccupation with

447
00:26:16.960 --> 00:26:19.720
<v Speaker 1>germs that came out of this. The September twenty twenty

448
00:26:19.759 --> 00:26:23.559
<v Speaker 1>study COVID nineteen and OCD Potential Impact of Exposure and

449
00:26:23.640 --> 00:26:28.160
<v Speaker 1>Response Prevention Therapy acknowledges right up top that the TSARS

450
00:26:28.240 --> 00:26:33.759
<v Speaker 1>COVID two coronavirus disease nineteen pandemic is the greatest international

451
00:26:33.880 --> 00:26:36.920
<v Speaker 1>health crisis in our modern era. So if you've been

452
00:26:36.960 --> 00:26:40.839
<v Speaker 1>on edge about microbes, just about COVID, that's just kind

453
00:26:40.880 --> 00:26:44.559
<v Speaker 1>of normal. This is a novel virus killing millions of people,

454
00:26:44.720 --> 00:26:47.759
<v Speaker 1>And to this day, half of reported COVID deaths in

455
00:26:47.799 --> 00:26:51.519
<v Speaker 1>the world are in the United States. The US has

456
00:26:51.680 --> 00:26:55.400
<v Speaker 1>half the deaths, and because of truly unhinged politics, half

457
00:26:55.480 --> 00:26:58.079
<v Speaker 1>the country won't wear masks or take a vaccine. So

458
00:26:58.160 --> 00:27:01.519
<v Speaker 1>what the fuck? But yeah, there are rational precautions in

459
00:27:01.599 --> 00:27:04.759
<v Speaker 1>a pandemic, and then there are OCD behaviors that prevent

460
00:27:04.880 --> 00:27:09.200
<v Speaker 1>you from daily functioning And reading through doctor Goodman's list

461
00:27:09.720 --> 00:27:14.319
<v Speaker 1>of published papers, so many of them, it's astonishing. I'm

462
00:27:14.319 --> 00:27:16.359
<v Speaker 1>going to be real with you, I started crying. And

463
00:27:16.440 --> 00:27:19.559
<v Speaker 1>how much work he's done in your research, which again

464
00:27:19.640 --> 00:27:25.039
<v Speaker 1>you've done so much research neurochemistry versus neurobiology. You mentioned serotonin,

465
00:27:25.119 --> 00:27:30.799
<v Speaker 1>You mentioned SSRIs as a treatment line or SNRIs have.

466
00:27:31.039 --> 00:27:34.160
<v Speaker 4>We you know your stuff, by the way, Unite didn't

467
00:27:34.200 --> 00:27:34.440
<v Speaker 4>really do.

468
00:27:34.519 --> 00:27:36.000
<v Speaker 1>It's because I'm on one of them.

469
00:27:37.400 --> 00:27:37.599
<v Speaker 5>I have.

470
00:27:38.640 --> 00:27:41.759
<v Speaker 1>I've got put on lamicdall actually after I was diagnosed

471
00:27:41.799 --> 00:27:43.960
<v Speaker 1>and it's been so I have questions about glutamate of

472
00:27:44.039 --> 00:27:48.880
<v Speaker 1>course too. So limotogen brand named Lamikdahl was developed for

473
00:27:48.960 --> 00:27:51.640
<v Speaker 1>the treatment of certain types of epilepsy because it slows

474
00:27:52.000 --> 00:27:56.079
<v Speaker 1>bursts of electrical activity that could cause seizures. But some

475
00:27:56.240 --> 00:28:02.279
<v Speaker 1>psychiatrists prescribe limotogene off label or depression associated with bipolar

476
00:28:02.519 --> 00:28:06.039
<v Speaker 1>and also for things like fibromyalgia, certain types of migraines,

477
00:28:06.200 --> 00:28:10.200
<v Speaker 1>panic disorder, binge eating disorder, and yep OCD. So the

478
00:28:10.319 --> 00:28:14.400
<v Speaker 1>twenty fifteen paper Role of loamotrogen Augmentation and Treatment Resistant

479
00:28:14.480 --> 00:28:19.119
<v Speaker 1>Obsessive Compulsive Disorder a Retrospective Case Review notes that genetic,

480
00:28:19.440 --> 00:28:24.720
<v Speaker 1>behavioral and neuroimaging studies have shown evidence of abnormally high

481
00:28:24.839 --> 00:28:28.400
<v Speaker 1>glutamaturgic concentrations in certain parts of the brains of people

482
00:28:28.440 --> 00:28:33.599
<v Speaker 1>with OCD, and adds that resistance to pharmacotherapy is one

483
00:28:33.680 --> 00:28:36.359
<v Speaker 1>of the major challenges in the management of OCD, but

484
00:28:36.559 --> 00:28:41.480
<v Speaker 1>one avenue for that is glutamaturgic modulators like lamotrogen. So

485
00:28:41.640 --> 00:28:43.400
<v Speaker 1>we're going to link a few other papers on our site,

486
00:28:43.440 --> 00:28:46.279
<v Speaker 1>but just something to explore maybe with your doctor. And

487
00:28:46.440 --> 00:28:50.559
<v Speaker 1>also because limotrogen can cause some severe allergic reactions in

488
00:28:50.640 --> 00:28:53.000
<v Speaker 1>some people, and it needs to be closely monitored. It

489
00:28:53.079 --> 00:28:55.200
<v Speaker 1>can also affect your white blood cell count. So talk

490
00:28:55.240 --> 00:28:58.400
<v Speaker 1>to an actual doctor because I'm not one, and Doctor

491
00:28:58.440 --> 00:29:01.319
<v Speaker 1>Goodman cannot treat or die ignows you from a podcast,

492
00:29:01.799 --> 00:29:04.319
<v Speaker 1>nor can you take a transcript of this podcast to

493
00:29:04.359 --> 00:29:08.319
<v Speaker 1>your pharmacist. But yeah, neurochemistry versus neurobiology is it a

494
00:29:08.400 --> 00:29:09.200
<v Speaker 1>combination of both.

495
00:29:10.559 --> 00:29:13.880
<v Speaker 4>So got through my own career, which we already established

496
00:29:13.920 --> 00:29:16.200
<v Speaker 4>has gone on for a long time. The first half

497
00:29:16.400 --> 00:29:21.160
<v Speaker 4>was more neurochemistry neurobiology, looking, for example, the role of serotonin,

498
00:29:21.240 --> 00:29:25.720
<v Speaker 4>and I published a lot of negative studies looking to

499
00:29:25.839 --> 00:29:30.599
<v Speaker 4>try to identify an abnormality in the brain the serotonin system,

500
00:29:30.720 --> 00:29:33.559
<v Speaker 4>and that's proved elusive, not only for me, but for

501
00:29:33.640 --> 00:29:37.759
<v Speaker 4>the whole field. And you mentioned glutamate. That's another neurotransmitter

502
00:29:37.920 --> 00:29:41.440
<v Speaker 4>that's been implicated in OCD, and there's some interesting work

503
00:29:41.519 --> 00:29:45.039
<v Speaker 4>on that and some medications that are being tried. But

504
00:29:45.519 --> 00:29:50.880
<v Speaker 4>at some point I pivoted more to looking at OCD

505
00:29:51.000 --> 00:29:54.880
<v Speaker 4>as a brain circuit disorder instead of a neurochemical disorder.

506
00:29:54.960 --> 00:29:58.559
<v Speaker 4>Not that serotonin clearly plays a role in treatment, but

507
00:29:58.599 --> 00:30:01.720
<v Speaker 4>it's not clear it plays a in the origins or

508
00:30:01.920 --> 00:30:05.440
<v Speaker 4>pathophysiology of the illness. So I started getting involved more

509
00:30:05.519 --> 00:30:08.599
<v Speaker 4>and looking at the brain circuits that mediate the symptoms

510
00:30:08.640 --> 00:30:09.160
<v Speaker 4>of OCD.

511
00:30:09.720 --> 00:30:11.920
<v Speaker 1>So he's been in the game so long, he's gone

512
00:30:12.000 --> 00:30:15.200
<v Speaker 1>deeper into the actual brain, and even in twenty twelve

513
00:30:15.480 --> 00:30:20.160
<v Speaker 1>published the study Deep Brain Stimulation for Intractable Psychiatric Disorders,

514
00:30:20.519 --> 00:30:23.960
<v Speaker 1>exploring treatments for patients who had exhausted other avenues. And

515
00:30:24.160 --> 00:30:28.559
<v Speaker 1>by helping these cases, he's also pioneering new understanding in

516
00:30:28.599 --> 00:30:29.640
<v Speaker 1>the process, and.

517
00:30:29.720 --> 00:30:33.960
<v Speaker 4>That's led me to different treatments, more neuromodulation, medical devices

518
00:30:34.640 --> 00:30:37.839
<v Speaker 4>instead of drugs, not that there's still a role for drugs,

519
00:30:37.960 --> 00:30:40.279
<v Speaker 4>and there's definitely The other thing we haven't touched on

520
00:30:40.440 --> 00:30:44.039
<v Speaker 4>we need to is the role of behavior therapy. If

521
00:30:44.079 --> 00:30:46.559
<v Speaker 4>I don't do that, my psychologist colleagues will be very

522
00:30:46.680 --> 00:30:47.240
<v Speaker 4>upset with me.

523
00:30:47.519 --> 00:30:52.079
<v Speaker 1>Damn right, Okay, So behavioral therapy, the right kind is huge.

524
00:30:52.160 --> 00:30:54.960
<v Speaker 1>We're going to get into that, especially the gold standard,

525
00:30:55.240 --> 00:30:58.680
<v Speaker 1>which is exposure response prevention or ERP therapy. And just

526
00:30:58.680 --> 00:31:00.519
<v Speaker 1>a little bit, but I do. I want to give

527
00:31:00.559 --> 00:31:04.680
<v Speaker 1>you some broad strokes of the neurobiology and the medication

528
00:31:04.799 --> 00:31:09.200
<v Speaker 1>options for OCD. So let's start with SSRIs. SSRI. It

529
00:31:09.279 --> 00:31:14.160
<v Speaker 1>stands for selective serotonin reuptake inhibitors, because these medications target

530
00:31:14.200 --> 00:31:17.240
<v Speaker 1>serotonin and they prevent it from getting sucked back up

531
00:31:17.359 --> 00:31:21.160
<v Speaker 1>into the brain cells, so there's more serotonin that stays

532
00:31:21.279 --> 00:31:24.960
<v Speaker 1>floating between the nerve cells to relay messages between them.

533
00:31:25.480 --> 00:31:27.880
<v Speaker 1>And there are a ton of other SSRIs on the

534
00:31:27.920 --> 00:31:30.039
<v Speaker 1>market as well that go buy a lot of different names.

535
00:31:30.359 --> 00:31:34.960
<v Speaker 1>Now SNRIs, they're not as selective as SNRI stands for

536
00:31:35.279 --> 00:31:40.039
<v Speaker 1>serotonin and nor epinephrine reuptake inhibitors, and they work to

537
00:31:40.160 --> 00:31:43.599
<v Speaker 1>keep more of both of those neurotransmitters between the cells,

538
00:31:43.960 --> 00:31:47.240
<v Speaker 1>so SNRIs can have fewer side effects and some people

539
00:31:47.680 --> 00:31:52.799
<v Speaker 1>than SSRIs do and SNRIs are sometimes prescribed for anxiety

540
00:31:52.920 --> 00:31:57.079
<v Speaker 1>and nerve pain. And limiicdol or Lamotrogene is neither an

541
00:31:57.200 --> 00:32:00.599
<v Speaker 1>SSRI or an SNRI. It's what's called a phenel triazine

542
00:32:00.680 --> 00:32:03.839
<v Speaker 1>drug and it's used to prevent seizures in types of epilepsy.

543
00:32:04.160 --> 00:32:06.720
<v Speaker 1>It's also used as a mood stabilizer, which can help

544
00:32:06.799 --> 00:32:10.039
<v Speaker 1>with bipolar depression, and it's been shown to modulate those

545
00:32:10.119 --> 00:32:12.839
<v Speaker 1>glutamate levels in the brain. We have a whole episode

546
00:32:12.920 --> 00:32:17.519
<v Speaker 1>on neurotransmitters. It's called molecular neurobiology with doctor Brain aka

547
00:32:17.680 --> 00:32:20.519
<v Speaker 1>doctor Crystal Delworth, which will link in the show notes.

548
00:32:20.720 --> 00:32:23.920
<v Speaker 1>But let's put that skull juice to work to learn

549
00:32:24.000 --> 00:32:27.079
<v Speaker 1>more about itself. Would you say that the majority of

550
00:32:27.160 --> 00:32:31.000
<v Speaker 1>cases can be helped with medication or is it really

551
00:32:31.160 --> 00:32:31.880
<v Speaker 1>a crapshoot?

552
00:32:34.240 --> 00:32:37.079
<v Speaker 4>Depends who you ask, Okay, but you're asking me, so

553
00:32:37.400 --> 00:32:40.240
<v Speaker 4>I would say, you know, it's really a lot up

554
00:32:40.359 --> 00:32:44.039
<v Speaker 4>to the patient. I mean, if I'm seeing a patient

555
00:32:44.039 --> 00:32:47.839
<v Speaker 4>who say I'm first diagnosing them with OCDA and they

556
00:32:47.920 --> 00:32:51.680
<v Speaker 4>have moderate OCD not severe OCDA, well a moderate is

557
00:32:51.720 --> 00:32:54.480
<v Speaker 4>through not great, I mean still can be quite distressing

558
00:32:54.559 --> 00:32:57.680
<v Speaker 4>and empairing. I would outline, you know, you have two options.

559
00:32:57.799 --> 00:33:00.039
<v Speaker 4>You can do the cognitive behavioral therapy, you can do

560
00:33:00.160 --> 00:33:02.960
<v Speaker 4>the medications, and I'll give the pros and cons. A

561
00:33:03.079 --> 00:33:05.480
<v Speaker 4>lot of patients will do well with one or the other,

562
00:33:06.160 --> 00:33:08.839
<v Speaker 4>and sometimes you wind up doing a combination of both.

563
00:33:09.759 --> 00:33:12.680
<v Speaker 1>Do SNRIs because they work in Europe and effort? Do

564
00:33:12.720 --> 00:33:15.920
<v Speaker 1>those tend to help with the anxiety that can be

565
00:33:16.640 --> 00:33:18.359
<v Speaker 1>a result of OCD.

566
00:33:19.480 --> 00:33:23.279
<v Speaker 4>That's a good theory. I like that theory, but if

567
00:33:23.319 --> 00:33:25.480
<v Speaker 4>you really want to be hardcore, and you look at

568
00:33:25.559 --> 00:33:30.079
<v Speaker 4>randomized control trials and peer review publications, the only medications

569
00:33:30.119 --> 00:33:34.400
<v Speaker 4>that have been shown effective or the SSRIs. The snri's

570
00:33:35.200 --> 00:33:38.799
<v Speaker 4>based upon clinical experience are also effective, and perhaps the

571
00:33:39.119 --> 00:33:43.440
<v Speaker 4>neurogenergic effects have some additional benefit, like you said, for anxiety.

572
00:33:43.759 --> 00:33:47.240
<v Speaker 4>But I'm not totally convinced. Okay, but I'm even skeptical

573
00:33:47.279 --> 00:33:50.640
<v Speaker 4>of my own work. You know, again, I've over the years,

574
00:33:50.880 --> 00:33:56.160
<v Speaker 4>I've tried different medications in our patients, maybe even published

575
00:33:56.160 --> 00:33:59.839
<v Speaker 4>a paper case report showing that it worked. But until

576
00:34:00.160 --> 00:34:04.440
<v Speaker 4>you subjected to the rigor of a randomized control trial.

577
00:34:04.480 --> 00:34:07.119
<v Speaker 4>And but I mean that, you know, a blinded study

578
00:34:07.200 --> 00:34:10.159
<v Speaker 4>where you randomize patients to either the drug or the placebo,

579
00:34:10.719 --> 00:34:11.880
<v Speaker 4>you don't really know the answer.

580
00:34:12.079 --> 00:34:15.760
<v Speaker 1>Yeah, And you mentioned that your work involves people who

581
00:34:15.840 --> 00:34:20.840
<v Speaker 1>have not been helped by what's typically administered. You do

582
00:34:20.960 --> 00:34:24.840
<v Speaker 1>deep brain stimulation. Can you explain what that is?

583
00:34:24.960 --> 00:34:27.920
<v Speaker 4>I work with brain surgeons, So the last twenty years,

584
00:34:28.000 --> 00:34:33.000
<v Speaker 4>I've been working with neurosurgeons, and they you do the

585
00:34:33.119 --> 00:34:37.480
<v Speaker 4>deep brain stimulation or DBS, and that's mostly a treatment

586
00:34:37.719 --> 00:34:43.360
<v Speaker 4>for movement disorders, like treatment resistant Parkinson's disorder. But we've

587
00:34:43.559 --> 00:34:47.039
<v Speaker 4>done studies together showing that it can be very effective

588
00:34:47.119 --> 00:34:49.840
<v Speaker 4>in patients with treatment resistant severe OCDA.

589
00:34:50.519 --> 00:34:55.079
<v Speaker 1>What is happening there? What are you stimulating? I picture

590
00:34:55.360 --> 00:34:58.000
<v Speaker 1>there being this OCD rope that you just go in

591
00:34:58.159 --> 00:35:00.960
<v Speaker 1>and cauterize, but I don't think that's how that works.

592
00:35:01.119 --> 00:35:01.800
<v Speaker 1>What happens.

593
00:35:02.519 --> 00:35:05.440
<v Speaker 4>It's a very complicated story and a very controversial one.

594
00:35:06.280 --> 00:35:09.440
<v Speaker 4>There's been so called psychosurgery. I hate that term because

595
00:35:09.480 --> 00:35:12.039
<v Speaker 4>it's brain surgery. It's not you know, nobody's operating on

596
00:35:12.079 --> 00:35:15.239
<v Speaker 4>your psyche. They're operating on your brain. But before the

597
00:35:15.360 --> 00:35:20.000
<v Speaker 4>introduction of deep brain stimulation, some surgeons at different centers,

598
00:35:20.119 --> 00:35:23.239
<v Speaker 4>both in the US and the UK, we're doing what's

599
00:35:23.280 --> 00:35:25.480
<v Speaker 4>called the blade of surgery. A blade of means actually

600
00:35:25.559 --> 00:35:29.639
<v Speaker 4>making allsion a small hole. And the theory behind that

601
00:35:30.559 --> 00:35:34.280
<v Speaker 4>is that there's this circuit, so let's identify those connections

602
00:35:34.360 --> 00:35:37.760
<v Speaker 4>between those two areas, between the obsessions and the compulsions,

603
00:35:38.280 --> 00:35:41.400
<v Speaker 4>and cut those connections and create allegiance. So that was

604
00:35:41.480 --> 00:35:45.599
<v Speaker 4>the hypothesis, and there have been many case reports and

605
00:35:45.800 --> 00:35:48.920
<v Speaker 4>case series showing that some of those patients with severe

606
00:35:48.960 --> 00:35:53.559
<v Speaker 4>OCD did very well with very few side effects, not

607
00:35:53.760 --> 00:35:56.480
<v Speaker 4>like the lobotomy era. You know, that's a totally different

608
00:35:56.559 --> 00:35:58.920
<v Speaker 4>kind of procedure. So that led to the theory that

609
00:35:59.440 --> 00:36:02.920
<v Speaker 4>you could use deep brain stimulation, which is not causing illsion,

610
00:36:03.400 --> 00:36:05.519
<v Speaker 4>but it's stimulating an area of the brain at a

611
00:36:05.639 --> 00:36:10.039
<v Speaker 4>high frequency that still interrupts those pathways. So the idea

612
00:36:10.119 --> 00:36:14.800
<v Speaker 4>is still behind DBS is somehow it's interrupting the OCD circuit,

613
00:36:14.880 --> 00:36:20.079
<v Speaker 4>this reverberating loot that's self reinforcing between obsessions and compulsions,

614
00:36:20.079 --> 00:36:22.440
<v Speaker 4>because that's part of the problem and the basis of

615
00:36:22.519 --> 00:36:26.679
<v Speaker 4>the exposure response prevention is the more a person performs

616
00:36:26.719 --> 00:36:30.480
<v Speaker 4>the compulsions, and the more effective those compulsions are in

617
00:36:30.639 --> 00:36:34.000
<v Speaker 4>reducing the angst associated with the obsessions, the more that's

618
00:36:34.039 --> 00:36:35.000
<v Speaker 4>going to become habitual.

619
00:36:36.079 --> 00:36:39.320
<v Speaker 1>Now is that kind of helpful in determining how genetic

620
00:36:39.400 --> 00:36:43.000
<v Speaker 1>it is if you're looking at brain anatomy or I

621
00:36:43.039 --> 00:36:45.079
<v Speaker 1>should just ask it straight up, but like how much

622
00:36:45.159 --> 00:36:46.159
<v Speaker 1>of this is genetic?

623
00:36:46.559 --> 00:36:52.800
<v Speaker 4>Yea, there's definitely a fair contribution of genetics. It's not simple. Yeah,

624
00:36:52.880 --> 00:36:56.199
<v Speaker 4>it's not simple medellion genetics where it seems to be

625
00:36:56.320 --> 00:36:58.880
<v Speaker 4>more genetic or in those patients that have both OCD

626
00:36:59.039 --> 00:37:01.719
<v Speaker 4>and Tourette syndrome, Oh right, that seems to be a

627
00:37:01.800 --> 00:37:03.320
<v Speaker 4>stronger genetic connection.

628
00:37:03.400 --> 00:37:06.800
<v Speaker 1>And the twenty fourteen paper Touret Syndrome and Obsessive Compulsive

629
00:37:06.840 --> 00:37:11.079
<v Speaker 1>disorder Compulsivity along the Continuum in the Journal of Obsessive

630
00:37:11.159 --> 00:37:15.519
<v Speaker 1>Compulsive and Related Disorders recaps some previous research that revealed

631
00:37:15.519 --> 00:37:20.000
<v Speaker 1>that genetic family studies have shown higher rates of OCD

632
00:37:20.159 --> 00:37:24.519
<v Speaker 1>symptoms or OCD in relatives of individuals with Turet syndrome,

633
00:37:24.920 --> 00:37:27.920
<v Speaker 1>and also research has shown higher rates of TICS or

634
00:37:28.079 --> 00:37:31.480
<v Speaker 1>Turet syndrome in first degree relatives of patients with OCD,

635
00:37:31.960 --> 00:37:35.679
<v Speaker 1>and the proportion of individuals with Thret syndrome who also

636
00:37:35.800 --> 00:37:39.920
<v Speaker 1>have OCD is up to sixty three percent, rather than

637
00:37:40.039 --> 00:37:43.119
<v Speaker 1>the general population rate of two to three percent. This

638
00:37:43.199 --> 00:37:47.840
<v Speaker 1>study notes that, however, despite the significant genetic overlap between

639
00:37:47.880 --> 00:37:53.320
<v Speaker 1>these disorders, Turet syndrome and OCD do have distinct genetic architectures,

640
00:37:53.760 --> 00:37:57.239
<v Speaker 1>and deep brain stimulation has been used to treat conditions

641
00:37:57.400 --> 00:38:01.760
<v Speaker 1>like Turet syndrome, Parkinson's disease, es central tremor epilepsy, and

642
00:38:01.840 --> 00:38:04.360
<v Speaker 1>of course, the reason that we are all here obsessive

643
00:38:04.519 --> 00:38:08.079
<v Speaker 1>compulsive disorder. I'm sorry, how though, does that work?

644
00:38:08.480 --> 00:38:10.079
<v Speaker 4>Going back to your question, though about to how the

645
00:38:10.159 --> 00:38:13.719
<v Speaker 4>DBS works. Yeah, I honestly don't. It's an area that

646
00:38:13.800 --> 00:38:16.840
<v Speaker 4>we're studying. But where it's implanted in the brain is

647
00:38:16.920 --> 00:38:19.639
<v Speaker 4>the reward circuitry, so the immediate effects. So I do

648
00:38:19.719 --> 00:38:23.280
<v Speaker 4>the programming of the device, the surgeon does the implantation,

649
00:38:24.119 --> 00:38:26.960
<v Speaker 4>and then after the recard from the surgery, which is

650
00:38:27.079 --> 00:38:30.920
<v Speaker 4>just overnight a week later, I can interrogate the device.

651
00:38:31.519 --> 00:38:33.360
<v Speaker 4>I can stimulate that area of the brain, and that

652
00:38:33.480 --> 00:38:35.519
<v Speaker 4>area of the brain is part of the reward circuitry,

653
00:38:36.320 --> 00:38:38.559
<v Speaker 4>and some of the immediate effects when I turn on

654
00:38:38.639 --> 00:38:42.119
<v Speaker 4>the stimulation are the person feels happier, they feel more

655
00:38:42.280 --> 00:38:46.599
<v Speaker 4>energetic and less anxious, and over time that leads to

656
00:38:46.679 --> 00:38:47.760
<v Speaker 4>reduction in OCDA.

657
00:38:48.360 --> 00:38:50.679
<v Speaker 1>How bad off do you have to be for? How

658
00:38:50.800 --> 00:38:57.199
<v Speaker 1>long before you get bumped up to the Goodman level treatment?

659
00:38:58.360 --> 00:38:58.559
<v Speaker 6>Yeah?

660
00:38:58.719 --> 00:39:01.360
<v Speaker 4>Yeah, it's not just me the only one, but there aren't.

661
00:39:01.559 --> 00:39:04.599
<v Speaker 4>It's not that many of us either. But you have

662
00:39:04.679 --> 00:39:06.800
<v Speaker 4>to have OCD for at least five years. Has to

663
00:39:06.840 --> 00:39:08.480
<v Speaker 4>be an adult. We won't do it in a kid.

664
00:39:09.519 --> 00:39:12.239
<v Speaker 4>A child, and it's got to be a y box

665
00:39:12.320 --> 00:39:14.639
<v Speaker 4>in the severe to extreme range, and they have to

666
00:39:14.760 --> 00:39:19.719
<v Speaker 4>have had multiple medication trials and failed ERP exposure response prevention.

667
00:39:20.239 --> 00:39:21.480
<v Speaker 1>Why does ERP work?

668
00:39:22.679 --> 00:39:25.039
<v Speaker 4>And Ken, let me say, ERP is not my specialty.

669
00:39:25.320 --> 00:39:28.719
<v Speaker 4>My psychologists colleagues are a specialist in that. But it

670
00:39:28.880 --> 00:39:31.280
<v Speaker 4>breaks this cycle. And we've talked a little bit about

671
00:39:31.320 --> 00:39:34.199
<v Speaker 4>OCD is kind of self reinforcing, and the idea is

672
00:39:34.719 --> 00:39:37.360
<v Speaker 4>with the surgical ideas, you interrupt that, and I think

673
00:39:37.400 --> 00:39:39.480
<v Speaker 4>with ERP you try to interrupt that too.

674
00:39:40.000 --> 00:39:43.400
<v Speaker 1>So cognitive behavior therapy is a type of brain retraining

675
00:39:43.559 --> 00:39:45.679
<v Speaker 1>and it comes in a lot of forms. One of

676
00:39:45.760 --> 00:39:51.239
<v Speaker 1>those is ERP or exposure response prevention, which involves exposing

677
00:39:51.519 --> 00:39:54.440
<v Speaker 1>yourself to the thoughts and confronting them and then the

678
00:39:54.679 --> 00:39:58.559
<v Speaker 1>prevention or making a choice not to do a compulsive

679
00:39:58.639 --> 00:40:02.199
<v Speaker 1>behavior wants the the anxiety or obsessions have been triggered.

680
00:40:02.320 --> 00:40:04.519
<v Speaker 1>They say, so you're like, oh, okay, so just like

681
00:40:04.599 --> 00:40:07.400
<v Speaker 1>don't do the thing, okay, cool, thanks, I promise. It's

682
00:40:07.480 --> 00:40:10.639
<v Speaker 1>not that simple, of course, and working with a therapist

683
00:40:10.719 --> 00:40:13.639
<v Speaker 1>trained an ERP, they'll help come up with a plan

684
00:40:14.000 --> 00:40:17.599
<v Speaker 1>to take small steps to retrain your brain. And according

685
00:40:17.639 --> 00:40:21.400
<v Speaker 1>to the International OCD Foundation, yes it's scary at first,

686
00:40:21.719 --> 00:40:24.840
<v Speaker 1>and that's the point, but when you do ERP correctly,

687
00:40:25.079 --> 00:40:27.480
<v Speaker 1>the following things happen, they say, you will feel an

688
00:40:27.519 --> 00:40:32.920
<v Speaker 1>initial increase, an anxiety, uncertainty, and obsessional thoughts. You will

689
00:40:33.000 --> 00:40:36.119
<v Speaker 1>find that these feelings and thoughts are distressing, but also

690
00:40:36.280 --> 00:40:40.159
<v Speaker 1>that they can't hurt you. They're safe and manageable. When

691
00:40:40.199 --> 00:40:44.239
<v Speaker 1>you stop fighting the obsessions and the anxiety, these feelings

692
00:40:44.360 --> 00:40:48.159
<v Speaker 1>will eventually begin to subside. And this natural drop and

693
00:40:48.199 --> 00:40:52.039
<v Speaker 1>anxiety that happens when you stay exposed and you prevent

694
00:40:52.440 --> 00:40:56.719
<v Speaker 1>the compulsive response is called habituation. So just staying in

695
00:40:56.800 --> 00:40:59.679
<v Speaker 1>it and confronting the fact that you're having these obsessive

696
00:40:59.719 --> 00:41:03.360
<v Speaker 1>thoughts without doing the compulsive response, you get used to that.

697
00:41:04.039 --> 00:41:06.679
<v Speaker 1>So you'll find that your fears are less likely to

698
00:41:06.760 --> 00:41:09.360
<v Speaker 1>come true than you thought, and then you'll get better

699
00:41:09.440 --> 00:41:14.119
<v Speaker 1>at managing everyday levels of risk and uncertainty. So doctor

700
00:41:14.159 --> 00:41:16.000
<v Speaker 1>Goodman explains the clinician's role.

701
00:41:16.440 --> 00:41:19.480
<v Speaker 4>What happens to people would have an obsession is they

702
00:41:19.559 --> 00:41:23.320
<v Speaker 4>try to perform a compulsion to reduce the anxiety. So

703
00:41:23.440 --> 00:41:25.719
<v Speaker 4>what you want to teach them in a behavior therapy

704
00:41:25.840 --> 00:41:31.400
<v Speaker 4>session is, don't perform your compulsion. Let's just wait and

705
00:41:31.559 --> 00:41:34.400
<v Speaker 4>tell me how how much distress you're feeling, maybe on

706
00:41:34.440 --> 00:41:37.519
<v Speaker 4>a scale to one to ten. Maybe it starts off

707
00:41:37.559 --> 00:41:41.920
<v Speaker 4>as an eight, but forty minutes later, even without performing compulsion,

708
00:41:42.360 --> 00:41:44.679
<v Speaker 4>is maybe down to a four, and you didn't have

709
00:41:44.760 --> 00:41:47.280
<v Speaker 4>to perform a compulsion. So you begin to teach the

710
00:41:47.320 --> 00:41:51.840
<v Speaker 4>person over time that they shouldn't try to avoid the obsessions.

711
00:41:51.840 --> 00:41:54.960
<v Speaker 4>They actually should try to let them come. So often

712
00:41:55.000 --> 00:41:58.840
<v Speaker 4>a metaphor is like, don't fight the waves, ride those waves.

713
00:41:59.400 --> 00:42:02.079
<v Speaker 4>The more you try to react to the OCD, the

714
00:42:02.199 --> 00:42:03.880
<v Speaker 4>more it's going to take a grip on your life.

715
00:42:04.679 --> 00:42:07.360
<v Speaker 1>And we've talked about the compulsions and what those look like,

716
00:42:07.800 --> 00:42:11.400
<v Speaker 1>but can you describe how your patients describe the obsessions?

717
00:42:11.599 --> 00:42:13.039
<v Speaker 1>How do other people describe them?

718
00:42:14.360 --> 00:42:18.320
<v Speaker 4>It really varies, but it's definitely intrusive. It's always disturbing,

719
00:42:18.880 --> 00:42:21.239
<v Speaker 4>and we may not have emphasized this enough. When we

720
00:42:21.360 --> 00:42:26.719
<v Speaker 4>talk about obsessions and OCD, we're talking about thoughts, images,

721
00:42:26.920 --> 00:42:31.239
<v Speaker 4>or unwanted impulses that are disturbing, and on the other

722
00:42:31.320 --> 00:42:35.280
<v Speaker 4>side of the coin, with compulsions, they're never pleasurable. So

723
00:42:35.400 --> 00:42:39.760
<v Speaker 4>we use the word compulsion very loosely, sometimes like compulsive eating,

724
00:42:40.239 --> 00:42:45.159
<v Speaker 4>compulsive gambling, compulsive sexual activity. Now, even though all those

725
00:42:45.280 --> 00:42:50.119
<v Speaker 4>could be problematic activities, especially like the gambling gets you

726
00:42:50.159 --> 00:42:52.000
<v Speaker 4>in a lot of trouble, or some of the drug

727
00:42:52.119 --> 00:42:54.719
<v Speaker 4>use can get you to some trouble. We may use

728
00:42:54.760 --> 00:42:57.519
<v Speaker 4>the word compulsive, but we wouldn't say that that has

729
00:42:57.559 --> 00:43:02.280
<v Speaker 4>any connection to OCD. At least at some point the

730
00:43:02.360 --> 00:43:07.199
<v Speaker 4>gambling was pleasurable. You got some gratification from certainly when

731
00:43:07.239 --> 00:43:12.920
<v Speaker 4>you want. In OCD, the compulsions are never gratifying. They

732
00:43:13.000 --> 00:43:17.440
<v Speaker 4>may reduce tension, they may reduce the anxiety associated with

733
00:43:17.519 --> 00:43:20.800
<v Speaker 4>the intrusive thoughts, but in and of themselves they're not

734
00:43:20.920 --> 00:43:22.079
<v Speaker 4>inherently gratifying.

735
00:43:22.920 --> 00:43:26.280
<v Speaker 1>So not like other compulsions. I'm like a less cool compulsion.

736
00:43:26.880 --> 00:43:30.599
<v Speaker 1>And doctor Goodman says that one consistent issue that OCD

737
00:43:30.679 --> 00:43:35.320
<v Speaker 1>sufferers have, no matter what the flavor is harm avoidance.

738
00:43:36.079 --> 00:43:39.400
<v Speaker 1>Harm to yourself and others becomes so terrifying that the

739
00:43:39.480 --> 00:43:42.760
<v Speaker 1>brain puts too much energy in trying to avoid it,

740
00:43:43.199 --> 00:43:46.559
<v Speaker 1>ultimately doing a harm to you and your life. And

741
00:43:46.639 --> 00:43:48.800
<v Speaker 1>I want to talk a little bit about comorbidities. And

742
00:43:49.000 --> 00:43:51.840
<v Speaker 1>we have questions from listeners who have they know what

743
00:43:51.960 --> 00:43:54.840
<v Speaker 1>you're coming on, and so they've submitted them ahead of time.

744
00:43:55.119 --> 00:43:57.440
<v Speaker 1>We also donate to a cause of your choice of

745
00:43:57.480 --> 00:43:59.920
<v Speaker 1>related cause, and I know there's an OCD walt coming

746
00:44:00.079 --> 00:44:04.159
<v Speaker 1>IOCDF Oh okay, great, perfect. We will donate to them

747
00:44:04.239 --> 00:44:06.079
<v Speaker 1>and shout them out and put a link for people

748
00:44:06.400 --> 00:44:10.760
<v Speaker 1>IOCDF no hesitation. I love that the International OCD Foundation

749
00:44:11.000 --> 00:44:14.119
<v Speaker 1>is a highly respected and core source for so much

750
00:44:14.199 --> 00:44:16.480
<v Speaker 1>support and info for folks who have OCD or know

751
00:44:16.599 --> 00:44:19.119
<v Speaker 1>someone who does. Their vision is that everyone impacted by

752
00:44:19.159 --> 00:44:22.800
<v Speaker 1>OCD and related disorders has immediate access to effective treatment

753
00:44:22.840 --> 00:44:26.559
<v Speaker 1>and support. And they provide up to date education and resources,

754
00:44:26.960 --> 00:44:31.760
<v Speaker 1>quality professional training, and they advance groundbreaking research and as

755
00:44:31.800 --> 00:44:34.960
<v Speaker 1>a leading nonprofit in the space. IOCDF has been around

756
00:44:35.000 --> 00:44:37.280
<v Speaker 1>since nineteen eighty six. It was co founded by a

757
00:44:37.280 --> 00:44:41.280
<v Speaker 1>guy named doctor Wayne Goodman. You may have heard of him. Also,

758
00:44:41.440 --> 00:44:44.119
<v Speaker 1>he asked that his honorarium for this show also be

759
00:44:44.199 --> 00:44:47.599
<v Speaker 1>donated to IOCDF dot org. So thank you to sponsors

760
00:44:47.679 --> 00:44:52.039
<v Speaker 1>of the show for making that double donation possible. Get value.

761
00:44:52.079 --> 00:44:55.079
<v Speaker 2>You can't argue with Optesco with their amazing club card prices.

762
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763
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764
00:45:00.920 --> 00:45:03.840
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765
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766
00:45:06.840 --> 00:45:09.920
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767
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768
00:45:14.639 --> 00:45:18.440
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769
00:45:18.519 --> 00:45:21.119
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770
00:45:22.480 --> 00:45:24.599
<v Speaker 1>So let's get in the mail bag of questions left

771
00:45:24.639 --> 00:45:27.639
<v Speaker 1>at patroon dot com sash ologies, where for one hot

772
00:45:27.719 --> 00:45:30.000
<v Speaker 1>dollar a month you can leave questions for the ologists

773
00:45:30.000 --> 00:45:32.400
<v Speaker 1>before we record. So a lot of you, Megan Walker,

774
00:45:32.440 --> 00:45:35.480
<v Speaker 1>are j Deutsche, Anonymous, Anastasia Press, Sarah Rose, Andy Pepper,

775
00:45:35.559 --> 00:45:38.960
<v Speaker 1>Kyra Black, Sarah Cork Henderson. First time question askers Jessica

776
00:45:39.159 --> 00:45:43.159
<v Speaker 1>Arrand and Benjamin Whiteley and Annie Eggelhoff asked well, Annie

777
00:45:43.199 --> 00:45:45.920
<v Speaker 1>put it this way, asking Hi, I am autistic and

778
00:45:46.000 --> 00:45:50.559
<v Speaker 1>have ADHD, OCD and dyslexia. Choosing the worst mental combo

779
00:45:50.679 --> 00:45:53.599
<v Speaker 1>meal ever has me wondering why it's so common to

780
00:45:53.679 --> 00:45:57.159
<v Speaker 1>have clusters of comorbidities like this as opposed to just

781
00:45:57.239 --> 00:45:59.639
<v Speaker 1>one of these disorders. Okay, a lot of people had

782
00:45:59.719 --> 00:46:04.239
<v Speaker 1>questions about co morbidities. Jessica Aaron said, as others are

783
00:46:04.239 --> 00:46:10.360
<v Speaker 1>asking what disorders are commonly comorbid with OCD, Anton also

784
00:46:10.519 --> 00:46:13.400
<v Speaker 1>asked how common is it for someone to just have OCD?

785
00:46:14.079 --> 00:46:16.559
<v Speaker 1>And also are there a lot of misdiagnoses while people

786
00:46:16.559 --> 00:46:17.679
<v Speaker 1>are trying to figure out what's going on?

787
00:46:18.719 --> 00:46:25.079
<v Speaker 4>Yeah, that happens a lot. The most common comorbidity is depression. Yeah, bomber,

788
00:46:25.639 --> 00:46:29.119
<v Speaker 4>particularly the more severe, the more treatment resistant, the longer

789
00:46:29.159 --> 00:46:34.119
<v Speaker 4>it's lasted. It's very common for patients to present with depression.

790
00:46:34.159 --> 00:46:36.840
<v Speaker 4>And that's what you know, I teach our residents our

791
00:46:36.880 --> 00:46:40.159
<v Speaker 4>Traineese is if you have a patient that's presenting with

792
00:46:41.079 --> 00:46:43.719
<v Speaker 4>either anxiety of course too as part of the syndrome

793
00:46:44.639 --> 00:46:48.039
<v Speaker 4>presenting with depression, it really behooves you to ask questions.

794
00:46:48.119 --> 00:46:50.559
<v Speaker 4>You know, do you have any behaviors that you feel

795
00:46:50.639 --> 00:46:53.639
<v Speaker 4>you have to perform over and over or any rituals

796
00:46:53.679 --> 00:46:56.480
<v Speaker 4>that you have to perform in order to reduce your anxiety?

797
00:46:56.639 --> 00:47:01.320
<v Speaker 4>Because again, one things I mentioned earlier is patients with

798
00:47:01.519 --> 00:47:06.960
<v Speaker 4>OCD by definition, have insight into the absurdity of their

799
00:47:07.039 --> 00:47:10.559
<v Speaker 4>thoughts and excessiveness of their behaviors. I'll tell you one example,

800
00:47:10.719 --> 00:47:13.679
<v Speaker 4>a patient of mine many years ago who came to

801
00:47:13.800 --> 00:47:17.280
<v Speaker 4>me was a software engineer, a very logical guy. And

802
00:47:17.360 --> 00:47:19.519
<v Speaker 4>he said, Doc, you're going to think I'm crazy. I've

803
00:47:19.599 --> 00:47:22.840
<v Speaker 4>never told this to anybody, but and this goes back

804
00:47:22.840 --> 00:47:24.360
<v Speaker 4>a few years. That's when you used to go to

805
00:47:24.440 --> 00:47:27.239
<v Speaker 4>the mailbox and mail a letter. And he said, I

806
00:47:27.280 --> 00:47:30.280
<v Speaker 4>can't mail a letter without wondering if my five year

807
00:47:30.320 --> 00:47:33.719
<v Speaker 4>old daughter is inside. And I said, Doc, you're going

808
00:47:33.760 --> 00:47:34.960
<v Speaker 4>to want to lock me up because I know you

809
00:47:35.000 --> 00:47:36.599
<v Speaker 4>can't put a five year old in the door. But

810
00:47:36.719 --> 00:47:40.039
<v Speaker 4>unless I check before I mail it, I worry something's

811
00:47:40.079 --> 00:47:42.840
<v Speaker 4>going to happen to her. So it was kind of

812
00:47:42.880 --> 00:47:45.880
<v Speaker 4>a metaphor for something happening to her. So it reached

813
00:47:45.880 --> 00:47:48.920
<v Speaker 4>the point where it became very physical that he would

814
00:47:48.960 --> 00:47:50.760
<v Speaker 4>have to look inside an envelope, he would have to

815
00:47:50.800 --> 00:47:53.559
<v Speaker 4>look at billboards that make sure she wasn't in the billboard.

816
00:47:54.000 --> 00:47:56.679
<v Speaker 4>And he actually did very well with treatment. But he

817
00:47:56.840 --> 00:47:59.960
<v Speaker 4>was completely logical, kept this as a secret from his family,

818
00:48:00.199 --> 00:48:01.000
<v Speaker 4>including his daughter.

819
00:48:02.079 --> 00:48:05.280
<v Speaker 1>And I've read of other people who are so afraid

820
00:48:05.320 --> 00:48:08.119
<v Speaker 1>that they hit someone on the road and didn't realize

821
00:48:08.119 --> 00:48:11.159
<v Speaker 1>it that have to drive back and check several times.

822
00:48:11.639 --> 00:48:14.280
<v Speaker 1>And it's interesting that harm avoidance is something that is

823
00:48:14.679 --> 00:48:17.480
<v Speaker 1>so common with so many patients of it, And again

824
00:48:17.559 --> 00:48:20.280
<v Speaker 1>we mentioned that the majority of compulsions can be covert

825
00:48:20.639 --> 00:48:24.760
<v Speaker 1>and not related to any outward behavior or rituals. But

826
00:48:24.960 --> 00:48:30.559
<v Speaker 1>what's the difference between strong preferences and compulsions? Patrons Jennifer

827
00:48:30.639 --> 00:48:34.760
<v Speaker 1>Lemon Think, Alicia Henning, Amelia Phillips, Valerie Kirby, d Austin Broadwater,

828
00:48:34.880 --> 00:48:36.920
<v Speaker 1>Mackenzie King, all of them asked, in the words of

829
00:48:37.159 --> 00:48:40.599
<v Speaker 1>s first time question asker, how do you disentangle OCD

830
00:48:40.800 --> 00:48:44.199
<v Speaker 1>from autism? Are they frequently comorbid when it comes to

831
00:48:44.559 --> 00:48:47.000
<v Speaker 1>rituals and things like that? Do you see folks who

832
00:48:47.039 --> 00:48:52.039
<v Speaker 1>are autistic who have trouble maybe understanding if it's OCD

833
00:48:52.199 --> 00:48:54.679
<v Speaker 1>versus if it's just like a rigidity that's comfort.

834
00:48:54.840 --> 00:48:56.840
<v Speaker 4>It's a great question, and it comes up a lot

835
00:48:57.039 --> 00:49:00.239
<v Speaker 4>because if you have somebody with autism who may have

836
00:49:00.400 --> 00:49:06.480
<v Speaker 4>some limited communication skills, they may have trouble explaining the obsessions,

837
00:49:06.519 --> 00:49:09.039
<v Speaker 4>so you have to infer them. So if they're doing

838
00:49:09.880 --> 00:49:13.880
<v Speaker 4>ritualized hand washing, or they're doing repeating getting in and

839
00:49:14.000 --> 00:49:16.320
<v Speaker 4>out of a chair, you can probably infer that they

840
00:49:16.400 --> 00:49:19.559
<v Speaker 4>have obsessions, even if you can't really identify them, and

841
00:49:19.760 --> 00:49:21.599
<v Speaker 4>you wind up treating them in the same way as

842
00:49:21.639 --> 00:49:22.559
<v Speaker 4>you would for OCD.

843
00:49:23.039 --> 00:49:26.679
<v Speaker 1>And how about for people who are verbal and aware

844
00:49:26.920 --> 00:49:30.800
<v Speaker 1>of their own rituals. Is there ever an overlap that

845
00:49:30.880 --> 00:49:34.119
<v Speaker 1>gets misdiagnosed where people maybe don't realize they have OCD

846
00:49:34.280 --> 00:49:37.239
<v Speaker 1>or don't realize that they have autism like eating the

847
00:49:37.320 --> 00:49:41.239
<v Speaker 1>same meal, essay, or sitting in the same spot.

848
00:49:41.559 --> 00:49:46.119
<v Speaker 4>It's somebody who's very ritualized. Yeah, yeah, that isn't necessarily OCD.

849
00:49:46.880 --> 00:49:48.400
<v Speaker 4>The other thing I would say is, although you can

850
00:49:48.480 --> 00:49:51.440
<v Speaker 4>have a monosymptomatic picture, meaning you know that maybe just

851
00:49:51.559 --> 00:49:56.239
<v Speaker 4>one type of OCD, most patients with OCD check off

852
00:49:56.519 --> 00:50:00.480
<v Speaker 4>different boxes. Sometimes when I'm not sure myself, I have

853
00:50:00.639 --> 00:50:03.360
<v Speaker 4>more confidence in the diagnosis when I find that over

854
00:50:03.519 --> 00:50:07.519
<v Speaker 4>time some of their obsessions and compulsions have changed and

855
00:50:07.679 --> 00:50:09.119
<v Speaker 4>that they check off different ones.

856
00:50:09.920 --> 00:50:15.880
<v Speaker 1>What about executive function and perfectionism or avoidance, things like

857
00:50:15.960 --> 00:50:20.320
<v Speaker 1>that people who might have trouble Yeah, like for example,

858
00:50:20.440 --> 00:50:25.760
<v Speaker 1>me getting set into worker work avoidance patrons Matt secafiin Crux,

859
00:50:25.880 --> 00:50:30.119
<v Speaker 1>chimber Issa a perfectionist but not OCD Haver and Alex

860
00:50:30.239 --> 00:50:33.400
<v Speaker 1>Rose first time question asker who asked, quite simply, why

861
00:50:33.519 --> 00:50:36.800
<v Speaker 1>is perfection OCD such a bitch, Where is the line

862
00:50:36.840 --> 00:50:39.239
<v Speaker 1>between perfectionism and OCD.

863
00:50:40.440 --> 00:50:46.039
<v Speaker 4>There is another condition, obsessive compulsive personality disorder that sometimes

864
00:50:46.079 --> 00:50:50.280
<v Speaker 4>it's hard to distinguish that from OCD, but that diagnosis

865
00:50:50.440 --> 00:50:57.320
<v Speaker 4>implies more perfectionism and insistence that others kind of follow rules,

866
00:50:58.119 --> 00:51:03.079
<v Speaker 4>and generally speaking, people with OCPD don't have a lot

867
00:51:03.159 --> 00:51:06.239
<v Speaker 4>of insight. Generally, what I've found is that it's their

868
00:51:06.320 --> 00:51:09.159
<v Speaker 4>family members who say, you really need to see somebody

869
00:51:09.440 --> 00:51:12.480
<v Speaker 4>because you're driving me crazy with wanting to do things

870
00:51:12.840 --> 00:51:15.639
<v Speaker 4>in your way all the time or in a certain

871
00:51:15.679 --> 00:51:18.519
<v Speaker 4>way all the time. So there is some connection, but

872
00:51:18.639 --> 00:51:20.840
<v Speaker 4>I think they're distinct most of the time.

873
00:51:21.239 --> 00:51:24.280
<v Speaker 1>And other experts note that the core difference lies in

874
00:51:24.360 --> 00:51:28.639
<v Speaker 1>the motivation behind perfectionist tendencies is that a high standard

875
00:51:29.000 --> 00:51:33.159
<v Speaker 1>is there a certain goal in mind. OCD related perfectionism, however,

876
00:51:33.320 --> 00:51:38.719
<v Speaker 1>may come from a place of extreme anxiety, catastrophizing, self criticism,

877
00:51:38.800 --> 00:51:43.400
<v Speaker 1>and doubt. So one compulsion is avoidance, and a nineteen

878
00:51:43.440 --> 00:51:47.719
<v Speaker 1>eighty four study titled Procrastination Tendencies among obsessive compulsives and

879
00:51:47.920 --> 00:51:53.079
<v Speaker 1>their relatives did find a correlation between OCD and task avoidance.

880
00:51:53.440 --> 00:51:57.039
<v Speaker 1>The author of that study is World renowned procrastination expert

881
00:51:57.280 --> 00:51:59.880
<v Speaker 1>doctor Joseph Ferrari, and if you're like, you should do

882
00:51:59.880 --> 00:52:03.079
<v Speaker 1>it izon with him, I did volitional psychology.

883
00:52:03.280 --> 00:52:03.639
<v Speaker 5>We did it.

884
00:52:03.719 --> 00:52:06.079
<v Speaker 1>It's linked in the show notes. His big advice is like,

885
00:52:06.440 --> 00:52:09.159
<v Speaker 1>just do the thing. He even signed my copy of

886
00:52:09.280 --> 00:52:12.599
<v Speaker 1>his book Still Procrastinating, the No Regrets Guide to Getting

887
00:52:12.599 --> 00:52:16.599
<v Speaker 1>It done, with the scrawl just do it now all caps.

888
00:52:17.079 --> 00:52:20.079
<v Speaker 1>At the time I was like, Joe, I can't, so

889
00:52:20.360 --> 00:52:22.679
<v Speaker 1>fuck me, I guess, And then I learned much later

890
00:52:22.920 --> 00:52:26.440
<v Speaker 1>that just do it now was just a little brusque

891
00:52:26.519 --> 00:52:30.559
<v Speaker 1>and a less gentle type of exposure response prevention. Essentially,

892
00:52:31.000 --> 00:52:34.039
<v Speaker 1>so until you stop procrastinating, you will not realize that

893
00:52:34.199 --> 00:52:38.679
<v Speaker 1>procrastinating and compulsive avoidance is worse than the thing you're

894
00:52:38.760 --> 00:52:41.920
<v Speaker 1>afraid to do poorly. And because of a therapist who

895
00:52:42.079 --> 00:52:46.079
<v Speaker 1>understood ERP, I have since adopted two phrases which are

896
00:52:46.199 --> 00:52:48.679
<v Speaker 1>essentially like bite sized takeaways that have helped me more

897
00:52:48.719 --> 00:52:52.760
<v Speaker 1>than anything else to tackle my decades long plague of

898
00:52:52.920 --> 00:52:56.320
<v Speaker 1>putting off the highest stakes tasks and avoiding them. So

899
00:52:56.519 --> 00:52:58.719
<v Speaker 1>I used to know myself as a last minute person

900
00:52:58.960 --> 00:53:02.320
<v Speaker 1>that was just like my vibe now when I see

901
00:53:02.320 --> 00:53:04.519
<v Speaker 1>an email or a form or a thing I have

902
00:53:04.639 --> 00:53:07.199
<v Speaker 1>to write, and I avoid it because what if I

903
00:53:07.280 --> 00:53:10.000
<v Speaker 1>do it wrong? I tell myself, I'm a person who

904
00:53:10.079 --> 00:53:12.320
<v Speaker 1>does things at the first minute, so that when a

905
00:53:12.480 --> 00:53:15.920
<v Speaker 1>task or email or decision or a draft of something

906
00:53:16.440 --> 00:53:19.760
<v Speaker 1>comes up, I decide or I started that first minute

907
00:53:19.880 --> 00:53:22.719
<v Speaker 1>or that first day, do not let it grow mold.

908
00:53:23.000 --> 00:53:24.760
<v Speaker 1>So I just say I'm a person who does things

909
00:53:24.800 --> 00:53:27.280
<v Speaker 1>at the first minute, to have me just jump right

910
00:53:27.320 --> 00:53:30.719
<v Speaker 1>into something. The other thing that exposure response prevention has

911
00:53:30.760 --> 00:53:32.679
<v Speaker 1>taught me to say to myself all the time is

912
00:53:33.159 --> 00:53:36.079
<v Speaker 1>worst things first, So what do you dread the most?

913
00:53:36.320 --> 00:53:39.079
<v Speaker 1>Do it first? If you don't want to do it, well,

914
00:53:39.199 --> 00:53:41.599
<v Speaker 1>it's therapy to get it done. And after a while

915
00:53:41.719 --> 00:53:44.280
<v Speaker 1>you say, wow, Okay, I did a bunch of things

916
00:53:44.280 --> 00:53:47.280
<v Speaker 1>I would have otherwise avoid. They did not kill me,

917
00:53:47.599 --> 00:53:49.800
<v Speaker 1>and I did not do such a bad job that

918
00:53:49.880 --> 00:53:53.000
<v Speaker 1>my whole life collapsed. So look, I made this episode,

919
00:53:53.400 --> 00:53:55.760
<v Speaker 1>and so far I have not died or killed anyone

920
00:53:55.960 --> 00:53:59.679
<v Speaker 1>in the process. Hooray. Now, speaking of putting some thoughts

921
00:53:59.719 --> 00:54:03.079
<v Speaker 1>into our little meatball brains, what about the thoughts that

922
00:54:03.239 --> 00:54:07.159
<v Speaker 1>we don't want around, the ones that barge into our

923
00:54:07.239 --> 00:54:10.039
<v Speaker 1>lives like a dinosaur made out of a grizzly bear

924
00:54:10.199 --> 00:54:12.960
<v Speaker 1>doing jazz hands through the wall like the Kool Aid Man.

925
00:54:13.360 --> 00:54:16.400
<v Speaker 1>Well patron Audrey Keen wrote, can you ask about intrusive

926
00:54:16.480 --> 00:54:19.159
<v Speaker 1>thoughts in OCD? I really do not want to drive

927
00:54:19.280 --> 00:54:21.639
<v Speaker 1>my car into a tree or touch a hot stove,

928
00:54:21.960 --> 00:54:24.159
<v Speaker 1>but in difficult times, my brain has yelled at me

929
00:54:24.239 --> 00:54:28.400
<v Speaker 1>to do such things. Honestly relatable and patrons love to learn.

930
00:54:28.440 --> 00:54:31.519
<v Speaker 1>Forty six Nicole Campbell, Ruby, Gordon Moss, Emily Staffer, and

931
00:54:31.880 --> 00:54:34.559
<v Speaker 1>Nasty garden Rat's friend wanted to know about these kind

932
00:54:34.559 --> 00:54:38.239
<v Speaker 1>of rude intrusions. Liliana, first time Questionascer wrote, sorry for

933
00:54:38.320 --> 00:54:41.239
<v Speaker 1>a rather intense question. I know many people with OCD

934
00:54:41.440 --> 00:54:45.119
<v Speaker 1>experience intrusive thoughts, and some, like my friend, have especially

935
00:54:45.239 --> 00:54:49.119
<v Speaker 1>distressing ones, such as pedophilic intrusive thoughts, or fears of

936
00:54:49.239 --> 00:54:52.800
<v Speaker 1>cheating or other scary and taboo topics. Could you speak

937
00:54:52.840 --> 00:54:57.679
<v Speaker 1>about why OCD often involves such intrusive thoughts, what causes them,

938
00:54:58.079 --> 00:55:00.800
<v Speaker 1>whether they're dangerous, and how people can manage them. We

939
00:55:00.960 --> 00:55:05.760
<v Speaker 1>mentioned intrusive thoughts, and sometimes all thoughts feel intrusive, but

940
00:55:06.199 --> 00:55:11.400
<v Speaker 1>can you explain exactly what an intrusive thought feels like

941
00:55:11.599 --> 00:55:14.840
<v Speaker 1>or when you know that thought is unwanted. Why you

942
00:55:14.920 --> 00:55:16.199
<v Speaker 1>can't just kind of swat it away.

943
00:55:17.360 --> 00:55:19.360
<v Speaker 4>Well, I can just go by what my patients tell me.

944
00:55:19.599 --> 00:55:20.400
<v Speaker 1>Yeah, and the other thing.

945
00:55:20.599 --> 00:55:24.199
<v Speaker 4>As long as you're on that point. There are patients

946
00:55:24.280 --> 00:55:28.800
<v Speaker 4>with psychotic conditions like schizophrenia may hear voices, right, They

947
00:55:28.840 --> 00:55:32.000
<v Speaker 4>may have auditory hallucinations, so they may hear a voice

948
00:55:32.480 --> 00:55:35.320
<v Speaker 4>that tells them something or tells them to do something.

949
00:55:36.119 --> 00:55:38.400
<v Speaker 4>One of the distinctions we make when we're making the

950
00:55:38.440 --> 00:55:42.079
<v Speaker 4>diagnosis of OCD. I'll ask the patient, well, it feels

951
00:55:42.159 --> 00:55:44.559
<v Speaker 4>like there's a voice in your head. Is that from

952
00:55:44.639 --> 00:55:47.480
<v Speaker 4>your own brain or you're actually hearing a voice? And

953
00:55:47.639 --> 00:55:49.400
<v Speaker 4>if they have OCD, it's oh no, no, I know

954
00:55:49.480 --> 00:55:51.800
<v Speaker 4>it's my brain, but it's like part of me is

955
00:55:51.880 --> 00:55:54.440
<v Speaker 4>telling me that I need to be careful, that something

956
00:55:54.519 --> 00:55:58.519
<v Speaker 4>terrible may happen, and until I do something about it,

957
00:55:59.320 --> 00:56:02.599
<v Speaker 4>the terrible feeling is going to linger. So I think

958
00:56:02.639 --> 00:56:04.400
<v Speaker 4>you're right. When I screened for somebody, I say, do

959
00:56:04.440 --> 00:56:06.840
<v Speaker 4>you ever have intrusive thoughts? You have thoughts that come

960
00:56:06.920 --> 00:56:09.039
<v Speaker 4>out of the blow and bother you. Everybody has them.

961
00:56:09.320 --> 00:56:13.760
<v Speaker 4>That doesn't distinguish OCD. It's really the combination of having

962
00:56:13.840 --> 00:56:17.800
<v Speaker 4>an intrusive thought that's unwanted, unpleasant, and the need to

963
00:56:17.920 --> 00:56:21.239
<v Speaker 4>do something about it, either physically or in terms of

964
00:56:21.599 --> 00:56:22.599
<v Speaker 4>a mental ritual.

965
00:56:23.800 --> 00:56:25.679
<v Speaker 1>We had a great question from someone named Rena who

966
00:56:26.079 --> 00:56:28.320
<v Speaker 1>very passionate requests. They say, can you talk about the

967
00:56:28.519 --> 00:56:32.199
<v Speaker 1>intrusive grippy sock type of OCD. I don't know if

968
00:56:32.239 --> 00:56:35.159
<v Speaker 1>you know that term, but grippysock vacation refers to an

969
00:56:35.280 --> 00:56:39.800
<v Speaker 1>impatient stay. But this person said that they were having

970
00:56:39.880 --> 00:56:42.960
<v Speaker 1>intrusive thoughts but they didn't seek help because they were

971
00:56:43.000 --> 00:56:45.880
<v Speaker 1>afraid of getting hospitalized for saying it out loud. And

972
00:56:46.039 --> 00:56:47.440
<v Speaker 1>they said, I think more people need to know the

973
00:56:47.480 --> 00:56:52.480
<v Speaker 1>difference between say, suicidal ideation or intent versus intrusive OCD

974
00:56:52.599 --> 00:56:57.400
<v Speaker 1>thoughts of self harm. How do clinicians parse that out?

975
00:56:58.159 --> 00:56:59.960
<v Speaker 1>And does that happen a lot where someone is having

976
00:57:00.079 --> 00:57:03.199
<v Speaker 1>intrusive thoughts without intent but it shoots them done the

977
00:57:03.199 --> 00:57:03.559
<v Speaker 1>wrong thing.

978
00:57:03.800 --> 00:57:07.920
<v Speaker 4>Yeah, that's a really good question too. So some patients

979
00:57:08.280 --> 00:57:12.320
<v Speaker 4>may have an intrusive thought that they may hurt themselves,

980
00:57:13.639 --> 00:57:16.880
<v Speaker 4>but what they'll tell me if they have OCDA is

981
00:57:16.960 --> 00:57:19.400
<v Speaker 4>they really don't want to hurt themselves. They have no plan,

982
00:57:19.559 --> 00:57:22.119
<v Speaker 4>they have no intent. It's the last thing I want

983
00:57:22.119 --> 00:57:24.559
<v Speaker 4>to do. But they're worried that if they don't do something,

984
00:57:25.280 --> 00:57:28.159
<v Speaker 4>perform some ritual, that somehow they're going to hurt themselves.

985
00:57:28.599 --> 00:57:31.960
<v Speaker 4>More often people are worried that's going to hurt someone

986
00:57:32.000 --> 00:57:36.119
<v Speaker 4>else rather than themselves. And when suicideality comes up, it's

987
00:57:36.239 --> 00:57:41.280
<v Speaker 4>usually because the person is very depressed, they feel demoralized,

988
00:57:41.320 --> 00:57:45.719
<v Speaker 4>they feel hopeless, maybe they feel embarrassed about their symptoms.

989
00:57:46.480 --> 00:57:48.639
<v Speaker 4>That's when suicideality comes to fruition.

990
00:57:49.079 --> 00:57:53.519
<v Speaker 1>We have an entire episode called Suicideology with suicidologists doctor

991
00:57:53.559 --> 00:57:56.559
<v Speaker 1>de Quincy Mayfriend Lazine, which we'll link for you in

992
00:57:56.880 --> 00:57:57.480
<v Speaker 1>the show notes.

993
00:57:57.639 --> 00:58:01.199
<v Speaker 4>And let me say something about a year of harming others.

994
00:58:01.639 --> 00:58:06.639
<v Speaker 4>That's a very common one, and there the questions come up. Well, say,

995
00:58:06.639 --> 00:58:09.760
<v Speaker 4>if you're an inexperienced clinician and somebody comes to you

996
00:58:09.920 --> 00:58:12.800
<v Speaker 4>and they're afraid they're gonna hurt somebody, I mean, what

997
00:58:12.960 --> 00:58:15.880
<v Speaker 4>you find out first? Do they ever hurt anybody you know? Intentionally?

998
00:58:16.280 --> 00:58:18.039
<v Speaker 4>And who are they afraid of hurting? Are they afraid

999
00:58:18.039 --> 00:58:20.840
<v Speaker 4>of hurting their boss who they hate? I don't know.

1000
00:58:21.000 --> 00:58:24.920
<v Speaker 4>Well maybe that's not Elday, I will to kill you

1001
00:58:25.360 --> 00:58:28.760
<v Speaker 4>right now, but we're they afraid of they can't babysit

1002
00:58:28.880 --> 00:58:32.360
<v Speaker 4>for their grandchild anymore because they're afraid they're gonna put

1003
00:58:32.400 --> 00:58:36.599
<v Speaker 4>their grandchild in the microwave. And they said, that's crazy,

1004
00:58:36.800 --> 00:58:39.440
<v Speaker 4>But I'm afraid they instead of baking the cake, I'm

1005
00:58:39.480 --> 00:58:43.119
<v Speaker 4>gonna put my grandchild in the microwave. So I can't

1006
00:58:43.159 --> 00:58:45.039
<v Speaker 4>babysit anymore. That's OCDA.

1007
00:58:46.639 --> 00:58:50.199
<v Speaker 1>When you mentioned harm others versus self, Mallory Albie wanted

1008
00:58:50.199 --> 00:58:52.960
<v Speaker 1>to know, is OCD associated with things like skin picking

1009
00:58:53.360 --> 00:58:55.400
<v Speaker 1>or hair pulling things like that? Is that under the

1010
00:58:55.440 --> 00:58:56.199
<v Speaker 1>OCD umbrella?

1011
00:58:57.159 --> 00:59:00.360
<v Speaker 4>The skin picking and hair pulling, trickletail and me is

1012
00:59:00.480 --> 00:59:05.199
<v Speaker 4>under this larger category, larger umbrella of OCD and related disorders,

1013
00:59:05.239 --> 00:59:09.400
<v Speaker 4>but they're considered distinct from OCD. You do see some coomorbidity,

1014
00:59:09.960 --> 00:59:13.679
<v Speaker 4>but they're separate and sometimes require different treatments.

1015
00:59:14.000 --> 00:59:18.199
<v Speaker 1>What about eating Deanna Day, Zoey Dunham, Mie Geoback and

1016
00:59:18.519 --> 00:59:22.039
<v Speaker 1>in Matt Secafan's words, what's known of the relationship between

1017
00:59:22.199 --> 00:59:28.000
<v Speaker 1>eating disorders and OCD? Same with disordered eating at all? Yeah.

1018
00:59:28.239 --> 00:59:31.960
<v Speaker 4>In terms of the relationship between eating disorders and OCD,

1019
00:59:32.440 --> 00:59:35.400
<v Speaker 4>the one where I see the strongest connection in some

1020
00:59:35.599 --> 00:59:40.440
<v Speaker 4>patients between anorexia nervosa and OCD. In fact, I've seen

1021
00:59:40.480 --> 00:59:44.559
<v Speaker 4>some patients over the years who may have started with

1022
00:59:45.360 --> 00:59:48.440
<v Speaker 4>anorexia nervosa with a focus has been more on their weight,

1023
00:59:49.199 --> 00:59:53.800
<v Speaker 4>and then they develop some rituals and other obsessions unrelated

1024
00:59:53.840 --> 00:59:57.519
<v Speaker 4>to their weight. So I see some connection there the

1025
00:59:57.639 --> 01:00:01.000
<v Speaker 4>idea of compulsive eating or belie. I don't see a

1026
01:00:01.039 --> 01:00:04.920
<v Speaker 4>strong connection between that and OCD. That's, in my mind,

1027
01:00:05.039 --> 01:00:07.119
<v Speaker 4>a misuse of the term compulsive.

1028
01:00:07.719 --> 01:00:10.599
<v Speaker 1>Okay, that's good to know. Some people wanted to know

1029
01:00:11.079 --> 01:00:14.639
<v Speaker 1>about infections, and Kapy Verregal asked how often is the

1030
01:00:14.719 --> 01:00:17.360
<v Speaker 1>onset of OCD preceded by an illness or infection, And

1031
01:00:17.480 --> 01:00:21.519
<v Speaker 1>a lot of people wanted to ask about PANDAS, which

1032
01:00:22.239 --> 01:00:25.440
<v Speaker 1>is a I'll put it in an aside pediatric autoimmune

1033
01:00:25.480 --> 01:00:30.039
<v Speaker 1>neuropsychiatric disorders associated with streptococcal infections, or say that three

1034
01:00:30.079 --> 01:00:34.679
<v Speaker 1>times fast, I cannot or pans. Okay, So PANTS stands

1035
01:00:34.760 --> 01:00:41.199
<v Speaker 1>for pediatric acute onset neuropsychiatric syndrome, and it's related to pandas.

1036
01:00:41.679 --> 01:00:47.280
<v Speaker 1>Cute names horrible conditions, and PANDAS stands for pediatric autoimmune

1037
01:00:47.400 --> 01:00:52.880
<v Speaker 1>neuropsychiatric disorders associated with streptococcal infections. No, I'm not going

1038
01:00:52.960 --> 01:00:54.639
<v Speaker 1>to say that three times. I just said it twice.

1039
01:00:55.000 --> 01:00:58.039
<v Speaker 1>That was hard enough. But according to the National Institute

1040
01:00:58.079 --> 01:01:02.880
<v Speaker 1>of Mental Health, these conditions affecting kiddos involve autoimmune encephalopathy

1041
01:01:03.320 --> 01:01:07.519
<v Speaker 1>or brain inflammation causing sudden and severe onset of OCD

1042
01:01:07.880 --> 01:01:12.480
<v Speaker 1>or restrictive eating disorder in children, and mood behavior and

1043
01:01:12.920 --> 01:01:15.679
<v Speaker 1>sensory and motor function can also be affected. But what

1044
01:01:15.880 --> 01:01:20.800
<v Speaker 1>doctors suspect triggers this are infections like PANDAS involves strap

1045
01:01:21.039 --> 01:01:24.519
<v Speaker 1>or scarlet fever, and in general, PANS may be triggered

1046
01:01:24.559 --> 01:01:28.880
<v Speaker 1>by immune system issues or illness or even environmental factors,

1047
01:01:29.159 --> 01:01:32.800
<v Speaker 1>and the conditions may start or stop suddenly. And for

1048
01:01:32.920 --> 01:01:36.239
<v Speaker 1>a while there was a lot of controversy on whether

1049
01:01:36.559 --> 01:01:40.360
<v Speaker 1>PANS or PANDAS were even real, and in twenty twelve

1050
01:01:40.440 --> 01:01:45.760
<v Speaker 1>Stanford University became the first academic institution to start treating it. Now,

1051
01:01:45.840 --> 01:01:50.239
<v Speaker 1>patrons including Anastasia Press, Aaron Sorenson, Nicholas Randall, Rayna William Russell,

1052
01:01:50.320 --> 01:01:53.559
<v Speaker 1>they all asked if PANDAS or PANS is the same

1053
01:01:53.639 --> 01:01:58.039
<v Speaker 1>as OCD, does treatment differ, and what's doctor Goodman's take

1054
01:01:58.119 --> 01:02:00.719
<v Speaker 1>on it? And Nicholas Randall echoed, Oh gosh, the pantas

1055
01:02:00.760 --> 01:02:02.280
<v Speaker 1>question would be so good to hear an answer to.

1056
01:02:02.639 --> 01:02:04.519
<v Speaker 1>But yeah, a lot of people wanted to know about this.

1057
01:02:04.639 --> 01:02:07.639
<v Speaker 1>It's something that typically the general population knows very little

1058
01:02:07.639 --> 01:02:09.920
<v Speaker 1>about unless you've known someone that has it. But can

1059
01:02:10.000 --> 01:02:12.760
<v Speaker 1>you talk about that and like sudden onsetting kids.

1060
01:02:12.920 --> 01:02:15.199
<v Speaker 4>Yeah, I've done some research on and some of my

1061
01:02:15.320 --> 01:02:18.519
<v Speaker 4>colleagues a more expert than I am. But it goes

1062
01:02:18.679 --> 01:02:21.639
<v Speaker 4>back to the reason when if you have a child

1063
01:02:21.840 --> 01:02:24.519
<v Speaker 4>then they have a sore throat. The reason you want

1064
01:02:24.559 --> 01:02:26.199
<v Speaker 4>to make sure it gets treated is you want to

1065
01:02:26.199 --> 01:02:29.199
<v Speaker 4>make sure it's not beta hemolytic STRAP, a strep infection,

1066
01:02:29.920 --> 01:02:32.960
<v Speaker 4>because with STRAP, this is unrelated to OCDAY, but I'll

1067
01:02:33.000 --> 01:02:36.360
<v Speaker 4>make the connection. The concern there is that some patients,

1068
01:02:36.440 --> 01:02:39.840
<v Speaker 4>if you failed to treat the STRAP infection adequately, you

1069
01:02:39.920 --> 01:02:44.119
<v Speaker 4>can get a complication called Sydenham's korea, which is auto

1070
01:02:44.159 --> 01:02:47.840
<v Speaker 4>antibodies directed against the brain. And Sue Sweeto, who came

1071
01:02:47.920 --> 01:02:51.000
<v Speaker 4>up with the idea of pannas many years ago, had

1072
01:02:51.079 --> 01:02:56.360
<v Speaker 4>identified a subpopulation of patients with OCD where they had

1073
01:02:56.400 --> 01:02:59.679
<v Speaker 4>a strep infection and instead of developing what was korea,

1074
01:03:00.599 --> 01:03:03.519
<v Speaker 4>Sinnham's korea, which is a certain type of movement disorder.

1075
01:03:04.039 --> 01:03:07.000
<v Speaker 4>They develop ticks or OCD symptoms out of the blue,

1076
01:03:07.159 --> 01:03:10.719
<v Speaker 4>kind of overnight. So it's a very interest, very fascinating.

1077
01:03:10.800 --> 01:03:14.239
<v Speaker 4>It's still controversial entity, but I think it does exist.

1078
01:03:14.760 --> 01:03:18.960
<v Speaker 4>It's hard to diagnose, and it's been expanded now to consideration.

1079
01:03:19.079 --> 01:03:22.320
<v Speaker 4>As you mentioned with PANS, not just focus on the strap,

1080
01:03:22.400 --> 01:03:26.840
<v Speaker 4>but maybe other infectious agents cause a autoimmune response where

1081
01:03:26.880 --> 01:03:30.760
<v Speaker 4>the antibodies attack your own brain and instead of producing

1082
01:03:30.840 --> 01:03:33.440
<v Speaker 4>Sinham's korea, you get ticks or OCD.

1083
01:03:33.800 --> 01:03:37.280
<v Speaker 1>Is the treatment for that still something serotonin or behavioral

1084
01:03:37.400 --> 01:03:41.159
<v Speaker 1>therapy or I've heard globulent therapy can be helpful for that.

1085
01:03:41.559 --> 01:03:43.639
<v Speaker 4>Yeah, I know there's some I'm not as up to

1086
01:03:43.719 --> 01:03:45.159
<v Speaker 4>date on the literature there, so I'm going to be

1087
01:03:45.199 --> 01:03:48.440
<v Speaker 4>a little bit careful about what I say about the latest.

1088
01:03:48.920 --> 01:03:50.719
<v Speaker 4>A lot of the patients that I see who are

1089
01:03:50.760 --> 01:03:55.320
<v Speaker 4>adults will raise questions about that they had OCD when

1090
01:03:55.320 --> 01:03:57.880
<v Speaker 4>they were a child, and could that be related to

1091
01:03:57.960 --> 01:04:02.480
<v Speaker 4>PANNED As it's possible if it's say five ten years,

1092
01:04:02.519 --> 01:04:06.280
<v Speaker 4>if transpired, I'm probably not going to try an immunal

1093
01:04:06.440 --> 01:04:09.800
<v Speaker 4>therapy because probably what even if there was an insult

1094
01:04:10.199 --> 01:04:13.400
<v Speaker 4>and an activation of the immune system. That inflammation is

1095
01:04:13.480 --> 01:04:17.760
<v Speaker 4>long gone, so we generally would treat it OCD kind

1096
01:04:17.760 --> 01:04:20.960
<v Speaker 4>of independent of whatever we think caused it, including PANDAS,

1097
01:04:21.320 --> 01:04:24.519
<v Speaker 4>so it would be the same treatments of behavior therapy

1098
01:04:24.880 --> 01:04:26.960
<v Speaker 4>or SSRIs for the most part.

1099
01:04:27.199 --> 01:04:29.760
<v Speaker 1>So yes, treatment varies depending on the case, but some

1100
01:04:30.039 --> 01:04:33.920
<v Speaker 1>first line therapies are treating the underlying STREP infection if

1101
01:04:33.960 --> 01:04:37.880
<v Speaker 1>that's still active, and going after the OCD challenges using

1102
01:04:38.000 --> 01:04:42.719
<v Speaker 1>cognitive behavioral therapy, perhaps also trying SSRIs or According to

1103
01:04:42.719 --> 01:04:46.320
<v Speaker 1>the twenty seventeen paper Clinical Management of Pediatric Acute on

1104
01:04:46.440 --> 01:04:51.719
<v Speaker 1>st Neuropsychiatric Syndrome, Part two, use of immunomodulatory therapies, immune

1105
01:04:51.760 --> 01:04:55.159
<v Speaker 1>abnormalities in seventy five to eighty percent of patients occur

1106
01:04:55.519 --> 01:05:01.119
<v Speaker 1>as inflammatory and post infectious autoimmune presentations, and that oral

1107
01:05:01.440 --> 01:05:06.159
<v Speaker 1>or IV cordico steroids may help, but IVY immunoglobulins or

1108
01:05:06.199 --> 01:05:10.079
<v Speaker 1>antibodies are the preferred treatment now for very severe cases.

1109
01:05:10.119 --> 01:05:14.320
<v Speaker 1>The paper continued, Therapeutic plasma exchange is the first line therapy,

1110
01:05:14.639 --> 01:05:18.719
<v Speaker 1>sometimes combined with immunoglobulins and the high doses of steroids

1111
01:05:18.760 --> 01:05:23.079
<v Speaker 1>and possibly retuximop which is an antibody medication used to

1112
01:05:23.159 --> 01:05:26.760
<v Speaker 1>treat certain autoimmune diseases like rheumatoid arthritis and cancers like

1113
01:05:26.840 --> 01:05:31.719
<v Speaker 1>non hodgkinslomphoma. And on the topic of neuroinflammation triggered by knowllness,

1114
01:05:31.800 --> 01:05:33.960
<v Speaker 1>we have a two part long COVID episode that just

1115
01:05:34.000 --> 01:05:35.880
<v Speaker 1>went up a few months ago with this amazing doctor,

1116
01:05:35.960 --> 01:05:38.079
<v Speaker 1>doctor Wes Eley, that will link in the show notes.

1117
01:05:38.119 --> 01:05:40.960
<v Speaker 1>And we also have an episode on multiple sclerosis coming

1118
01:05:41.000 --> 01:05:43.159
<v Speaker 1>up very soon. But I'm grateful to say I have

1119
01:05:43.239 --> 01:05:45.639
<v Speaker 1>some kiddos in my life who have had pandas went

1120
01:05:45.719 --> 01:05:49.400
<v Speaker 1>to this exact Stanford Pants clinic and are doing amazing.

1121
01:05:49.760 --> 01:05:53.840
<v Speaker 1>So if anyone from that clinic Stanford is listening, thank

1122
01:05:53.920 --> 01:05:57.039
<v Speaker 1>you from the bottom of this lady's heart. It's really

1123
01:05:57.159 --> 01:06:00.000
<v Speaker 1>challenging to find doctors who are looking at different times

1124
01:06:00.199 --> 01:06:02.039
<v Speaker 1>of treatment for this, but it's heartening to see that

1125
01:06:02.079 --> 01:06:04.480
<v Speaker 1>it's become more widely known and treated now. If you

1126
01:06:04.639 --> 01:06:06.639
<v Speaker 1>think that your kid is struggling with this, the National

1127
01:06:06.719 --> 01:06:09.280
<v Speaker 1>Institute of Mental Health recommends that you reach out to

1128
01:06:09.440 --> 01:06:13.960
<v Speaker 1>the wonderful International OCD Foundation or the Panda's Physicians Network

1129
01:06:14.199 --> 01:06:17.199
<v Speaker 1>to find a healthcare provider who may be knowledgeable about

1130
01:06:17.239 --> 01:06:20.079
<v Speaker 1>pants and pandas we'll link that on our website. And

1131
01:06:20.559 --> 01:06:22.639
<v Speaker 1>you know, we talked about a little bit about like

1132
01:06:22.760 --> 01:06:25.360
<v Speaker 1>a childhood situation. I know we're throwing around a lot

1133
01:06:25.440 --> 01:06:29.119
<v Speaker 1>of letters when it comes to complex BTSD. Some folks,

1134
01:06:29.519 --> 01:06:33.679
<v Speaker 1>Jordan Iron's, Kayla Tozier, Will Clark, Alex miner Orlsur Reese

1135
01:06:33.800 --> 01:06:37.639
<v Speaker 1>Perini wanted to know is OCD, in Reese's words, sometimes

1136
01:06:37.719 --> 01:06:40.840
<v Speaker 1>trauma induced. Do you see that in any patients? Kyla

1137
01:06:40.840 --> 01:06:42.719
<v Speaker 1>wanted to know who childhood trauma lye to OCD.

1138
01:06:43.559 --> 01:06:46.840
<v Speaker 4>I've seen some cases over the years where I thought

1139
01:06:46.880 --> 01:06:49.519
<v Speaker 4>that there was a direct connection between a traumatic life

1140
01:06:49.599 --> 01:06:53.039
<v Speaker 4>event and the OCDA, but it's not all that common

1141
01:06:53.119 --> 01:06:56.159
<v Speaker 4>in my experience. I remember one patient I treated who

1142
01:06:56.199 --> 01:06:59.519
<v Speaker 4>was a combat veteran and he had an awful job

1143
01:06:59.800 --> 01:07:03.960
<v Speaker 4>of This was in the Vietnam era of doing body counts.

1144
01:07:04.000 --> 01:07:07.719
<v Speaker 4>Oh and it was obviously a very traumatic experience and

1145
01:07:08.719 --> 01:07:10.960
<v Speaker 4>he developed OCD after that, and I thought it was

1146
01:07:11.039 --> 01:07:12.079
<v Speaker 4>definitely a connection.

1147
01:07:12.639 --> 01:07:14.360
<v Speaker 1>Well, well, well look at that. A twenty twenty four

1148
01:07:14.400 --> 01:07:18.039
<v Speaker 1>study titled exploring the Interplay between complex post traumatic stress

1149
01:07:18.079 --> 01:07:22.800
<v Speaker 1>Disorder and obsessive compulsive disorder severity Implications for Clinical Practice,

1150
01:07:23.039 --> 01:07:26.119
<v Speaker 1>which opens with a banger of a sentence. Traumatic events

1151
01:07:26.360 --> 01:07:30.400
<v Speaker 1>adversely affect the clinical course of obsessive compulsive disorder, and

1152
01:07:30.599 --> 01:07:35.119
<v Speaker 1>the paper concludes that the coexistence of CPTSD in OCD

1153
01:07:35.760 --> 01:07:41.800
<v Speaker 1>exacerbates obsessive compulsive symptoms and increases the burden of anxiety. So, yeah,

1154
01:07:41.880 --> 01:07:44.400
<v Speaker 1>you know you're not imagining that. And here I just

1155
01:07:44.480 --> 01:07:47.719
<v Speaker 1>have to shout out one of my favorite musicians, Alison Pontier,

1156
01:07:47.880 --> 01:07:51.360
<v Speaker 1>who not only has the voice of an angel. You

1157
01:07:51.440 --> 01:07:54.480
<v Speaker 1>may have heard her EPs Faking my own death and

1158
01:07:54.760 --> 01:07:57.440
<v Speaker 1>shaking hands with Elvis the last few years, or her

1159
01:07:57.480 --> 01:07:59.400
<v Speaker 1>feature on Lord Here on song.

1160
01:07:59.400 --> 01:08:09.800
<v Speaker 5>Eyeled Bucks of jobs.

1161
01:08:08.679 --> 01:08:11.840
<v Speaker 1>But also last week released an essay on substack about

1162
01:08:11.880 --> 01:08:16.359
<v Speaker 1>her OCD titled Manifesting but Evil What I couldn't tell anyone,

1163
01:08:16.600 --> 01:08:18.399
<v Speaker 1>and I'll link it on our website, but it opens

1164
01:08:18.800 --> 01:08:21.399
<v Speaker 1>around age eleven, I discovered that if I made deals

1165
01:08:21.439 --> 01:08:24.600
<v Speaker 1>with God, my stomach wouldn't hurt anymore, at least until

1166
01:08:24.600 --> 01:08:27.119
<v Speaker 1>the next time it happened. God isn't big on money

1167
01:08:27.319 --> 01:08:31.359
<v Speaker 1>or favors. He's mostly interested in meaningless tasks performed in

1168
01:08:31.439 --> 01:08:34.680
<v Speaker 1>exchange for a few minutes of relief Now. On Allison's

1169
01:08:34.720 --> 01:08:37.760
<v Speaker 1>Instagram post about it, the comments flooded in like ex

1170
01:08:37.880 --> 01:08:42.159
<v Speaker 1>Religious OCD, Eva's rise up and religious OCD plus magical

1171
01:08:42.199 --> 01:08:45.319
<v Speaker 1>thinking OCD were rude and I was really moved by

1172
01:08:45.520 --> 01:08:49.159
<v Speaker 1>her essay and I found it relatable as well. Hell

1173
01:08:49.680 --> 01:08:52.079
<v Speaker 1>and Olivia Lester wanted to know if there's a correlation

1174
01:08:52.199 --> 01:08:57.039
<v Speaker 1>between OCD and Judaism. I was personally raised Catholic, and

1175
01:08:57.119 --> 01:09:01.399
<v Speaker 1>if there's ever an obsessive in convulsion, Catholicism is like,

1176
01:09:01.880 --> 01:09:03.920
<v Speaker 1>you will go to Hell unless you say this rosary

1177
01:09:04.000 --> 01:09:06.800
<v Speaker 1>the exact number of times, you know what I mean,

1178
01:09:06.960 --> 01:09:09.399
<v Speaker 1>Like that they send you to penance. So do you

1179
01:09:09.479 --> 01:09:11.880
<v Speaker 1>ever see people with maybe religious backgrounds that.

1180
01:09:11.920 --> 01:09:16.079
<v Speaker 4>Are oh yeah, yeah all the time. And definitely a

1181
01:09:16.119 --> 01:09:19.640
<v Speaker 4>lot of Catholics for sure. In fact, some of the earliest,

1182
01:09:19.760 --> 01:09:22.760
<v Speaker 4>probably some of the earliest descriptions of OCD that correspond

1183
01:09:22.840 --> 01:09:25.880
<v Speaker 4>to our current definitions go back to the Catholic Church

1184
01:09:26.560 --> 01:09:29.520
<v Speaker 4>referring to scrupulosity. In fact, I don't know if it

1185
01:09:29.600 --> 01:09:32.079
<v Speaker 4>still exists, but there's a treatment center in the Midwest

1186
01:09:32.680 --> 01:09:36.000
<v Speaker 4>for priests who were scrupulous. They were taking the biblical

1187
01:09:36.039 --> 01:09:38.680
<v Speaker 4>studies too literally, and so one of the things when

1188
01:09:38.720 --> 01:09:42.000
<v Speaker 4>I I'm Jewish, and I certainly I've had Jewish and

1189
01:09:42.199 --> 01:09:45.399
<v Speaker 4>Catholic and people from all walks of life, all religions

1190
01:09:45.439 --> 01:09:48.079
<v Speaker 4>who have had OCD, and some of them do involve

1191
01:09:48.479 --> 01:09:51.560
<v Speaker 4>religious ideation. And what I will ask him is have

1192
01:09:51.720 --> 01:09:54.800
<v Speaker 4>you have you sought out your priest, your rabbi, and

1193
01:09:55.079 --> 01:09:58.199
<v Speaker 4>have they tried to reassure you that you're over interpreting

1194
01:09:58.279 --> 01:10:02.439
<v Speaker 4>these concerns And usually that doesn't work. My experience is

1195
01:10:02.479 --> 01:10:05.199
<v Speaker 4>that that kind of reassurance doesn't cure the OCD.

1196
01:10:05.600 --> 01:10:07.880
<v Speaker 1>The priest is like, no, yeah, you do have to

1197
01:10:08.000 --> 01:10:10.479
<v Speaker 1>do this. That's interesting that Catholic literature some of the

1198
01:10:10.520 --> 01:10:13.119
<v Speaker 1>first but Keithan Newman and Linda English wanted to know

1199
01:10:13.159 --> 01:10:15.680
<v Speaker 1>about hoarding. Does it ever bother you when you see

1200
01:10:16.079 --> 01:10:18.920
<v Speaker 1>shows like or hear of shows like Quarters where they're like,

1201
01:10:18.960 --> 01:10:21.039
<v Speaker 1>we're just going to come in and clean up your

1202
01:10:21.039 --> 01:10:23.560
<v Speaker 1>house and you're going to be fine, When it's so

1203
01:10:23.760 --> 01:10:27.119
<v Speaker 1>much deeper than that. Is that under the OCD umbrella again.

1204
01:10:26.960 --> 01:10:29.720
<v Speaker 4>It's separate against under the same umbrella of OCD and

1205
01:10:29.800 --> 01:10:34.199
<v Speaker 4>related to sourders. Sometimes they're connected, other times hoardings is separate.

1206
01:10:34.600 --> 01:10:38.319
<v Speaker 4>I'll give you an anecdote patient. This years ago gotten

1207
01:10:38.359 --> 01:10:42.479
<v Speaker 4>to the point where she collected her cat litter in

1208
01:10:42.560 --> 01:10:45.000
<v Speaker 4>bags because she was afraid that the cat would ingest

1209
01:10:45.079 --> 01:10:47.920
<v Speaker 4>something valuable. And she pointed out that she really didn't

1210
01:10:47.920 --> 01:10:51.399
<v Speaker 4>own anything valuable, but nevertheless, she was worried that something

1211
01:10:51.439 --> 01:10:53.600
<v Speaker 4>would be thrown out in the trash that was valuable,

1212
01:10:53.800 --> 01:10:56.800
<v Speaker 4>including the in the cat letter. And you can imagine,

1213
01:10:56.960 --> 01:10:59.880
<v Speaker 4>you know, collecting bags of cat litter in your base.

1214
01:11:00.840 --> 01:11:03.199
<v Speaker 4>So her husband took advantage of a weekend when she

1215
01:11:03.319 --> 01:11:06.760
<v Speaker 4>was visiting her sister, brought in a dumpster and he

1216
01:11:06.840 --> 01:11:09.680
<v Speaker 4>and his friends decide to clear out the house. She

1217
01:11:09.800 --> 01:11:14.880
<v Speaker 4>came home early and she did a dumpster dive. So

1218
01:11:14.960 --> 01:11:18.039
<v Speaker 4>it did not work. That approach doesn't work.

1219
01:11:18.720 --> 01:11:20.479
<v Speaker 1>Just a fun side note. We have an episode on

1220
01:11:20.640 --> 01:11:24.560
<v Speaker 1>decluttering called Oecology and the expert in it is named

1221
01:11:24.720 --> 01:11:28.560
<v Speaker 1>Jamie Hord. But simply Marie, condoing your house is not

1222
01:11:28.600 --> 01:11:31.680
<v Speaker 1>going to do the full trick. Results on medical trials

1223
01:11:31.760 --> 01:11:34.920
<v Speaker 1>for hoarding disorder have been a little mostly focused on

1224
01:11:35.479 --> 01:11:39.840
<v Speaker 1>SSRIs which have been a little effective, although SNRIs and

1225
01:11:40.000 --> 01:11:44.880
<v Speaker 1>glutamate modulators or ADHD medications may show some promise, but

1226
01:11:45.039 --> 01:11:48.199
<v Speaker 1>a ton more research is needed, so for now, the

1227
01:11:48.359 --> 01:11:51.560
<v Speaker 1>best treatment for hoarding disorder seems to be cognitive behavioral

1228
01:11:51.680 --> 01:11:55.199
<v Speaker 1>therapy and usually a lot of support from caregivers or

1229
01:11:55.279 --> 01:11:59.199
<v Speaker 1>loved ones. And hoarding disorder, remember isn't OCD, although some

1230
01:11:59.399 --> 01:12:02.479
<v Speaker 1>folks can struggle with both. Now, what if some of

1231
01:12:02.640 --> 01:12:06.239
<v Speaker 1>this OCD info is hitting a little too close to home?

1232
01:12:06.479 --> 01:12:08.640
<v Speaker 1>But you also don't want to diagnose yourself from a

1233
01:12:08.760 --> 01:12:11.720
<v Speaker 1>one hour long podcast episode? Do you have any advice

1234
01:12:11.800 --> 01:12:14.600
<v Speaker 1>for someone who suspects that they might have OCD in

1235
01:12:14.720 --> 01:12:18.920
<v Speaker 1>terms of how to seek help and how to how

1236
01:12:19.000 --> 01:12:21.000
<v Speaker 1>to really recognize the impact that it's having.

1237
01:12:21.840 --> 01:12:23.399
<v Speaker 4>So I want to put a blog in for the

1238
01:12:23.520 --> 01:12:26.760
<v Speaker 4>International OCD Foundation that I was a co founder of

1239
01:12:26.800 --> 01:12:30.680
<v Speaker 4>that organization back in the eighties. Go to their website.

1240
01:12:30.760 --> 01:12:34.640
<v Speaker 4>They have a lot of great information. They identify different

1241
01:12:34.920 --> 01:12:37.960
<v Speaker 4>places where you can seek treatment. So I think that's

1242
01:12:38.000 --> 01:12:38.920
<v Speaker 4>a good starting point.

1243
01:12:39.520 --> 01:12:43.239
<v Speaker 1>What about for people who's loved ones might have OCD?

1244
01:12:43.359 --> 01:12:45.720
<v Speaker 1>Anonymous wanted to know about living with someone with OCD,

1245
01:12:45.920 --> 01:12:48.359
<v Speaker 1>both in ways to help and ways to cope, and

1246
01:12:48.760 --> 01:12:51.760
<v Speaker 1>Elena Grilla also wanted to know any tips on coping,

1247
01:12:52.479 --> 01:12:56.199
<v Speaker 1>how to support but also not enable too many compulsions.

1248
01:12:57.439 --> 01:12:59.920
<v Speaker 4>Yeah, you know, that's a tough struggle for love one

1249
01:13:00.000 --> 01:13:03.720
<v Speaker 4>ones you talk about enabling, you don't want to enable.

1250
01:13:04.039 --> 01:13:06.920
<v Speaker 4>But also if you have a loved one who's in distressed,

1251
01:13:07.039 --> 01:13:08.439
<v Speaker 4>or you have to make it to a dinner date

1252
01:13:08.520 --> 01:13:11.720
<v Speaker 4>together and they say, well, you got a check, or

1253
01:13:11.800 --> 01:13:15.439
<v Speaker 4>they're asking for your reassurance that they did something correctly,

1254
01:13:15.560 --> 01:13:17.439
<v Speaker 4>or that they have to check the locks again or

1255
01:13:17.520 --> 01:13:18.520
<v Speaker 4>the stove, or.

1256
01:13:18.600 --> 01:13:22.279
<v Speaker 1>In the case of say moral scrupulosity OCD involving ruminations

1257
01:13:22.359 --> 01:13:24.880
<v Speaker 1>worrying that you're not a good or moral person or

1258
01:13:24.920 --> 01:13:28.800
<v Speaker 1>that you're always harming people. Reassurance seeking may come in

1259
01:13:28.880 --> 01:13:31.760
<v Speaker 1>the form of asking loved ones over and over if

1260
01:13:31.760 --> 01:13:34.840
<v Speaker 1>you've done anything wrong. Now, with a therapist who doesn't

1261
01:13:34.880 --> 01:13:38.479
<v Speaker 1>specialize in OCD, you may just run around in circles

1262
01:13:38.560 --> 01:13:42.760
<v Speaker 1>treatment wise, just asking your therapist for reassurance and getting it,

1263
01:13:43.039 --> 01:13:45.199
<v Speaker 1>but not getting to the root of the issue or

1264
01:13:45.399 --> 01:13:49.279
<v Speaker 1>confronting those obsessions and compulsions. And also, I said enable,

1265
01:13:49.319 --> 01:13:52.239
<v Speaker 1>but I meant accommodate. My brain did not do a word.

1266
01:13:52.560 --> 01:13:55.800
<v Speaker 4>Well, it's easy just to give into it because that's

1267
01:13:55.800 --> 01:13:59.119
<v Speaker 4>the most parsimonious thing to do. So it's there's no

1268
01:13:59.319 --> 01:14:04.119
<v Speaker 4>one script. I think if somebody is going for exposure

1269
01:14:04.199 --> 01:14:07.319
<v Speaker 4>response prevention. It's really important for the family members to

1270
01:14:07.399 --> 01:14:12.239
<v Speaker 4>participate so that they're not inadverently accommodating the symptoms, but

1271
01:14:12.439 --> 01:14:15.840
<v Speaker 4>also not looking like they show feeling no empathy for

1272
01:14:15.960 --> 01:14:19.439
<v Speaker 4>the person's feelings. It's easy to say from the outside

1273
01:14:19.600 --> 01:14:22.600
<v Speaker 4>just stop it, yeah, but it isn't for the patient

1274
01:14:22.600 --> 01:14:23.880
<v Speaker 4>who has OCD.

1275
01:14:24.079 --> 01:14:28.439
<v Speaker 1>Especially if the stakes are typically so high where you're

1276
01:14:28.479 --> 01:14:29.439
<v Speaker 1>asking someone.

1277
01:14:29.279 --> 01:14:32.079
<v Speaker 4>To or like going to going to hell, yeah, going

1278
01:14:32.159 --> 01:14:32.720
<v Speaker 4>to hell.

1279
01:14:32.800 --> 01:14:36.119
<v Speaker 1>Or giving someone an illness that could kill them. Just

1280
01:14:36.159 --> 01:14:38.279
<v Speaker 1>this notion that like if I don't do this correctly,

1281
01:14:38.359 --> 01:14:40.359
<v Speaker 1>I could kill someone. It's not as easy as just

1282
01:14:40.439 --> 01:14:45.199
<v Speaker 1>not doing it, you know. And any biggest myths, last questions,

1283
01:14:45.199 --> 01:14:47.680
<v Speaker 1>any biggest myths that you want to stand on a

1284
01:14:47.720 --> 01:14:49.560
<v Speaker 1>soapbox and flim flamm you.

1285
01:14:49.600 --> 01:14:50.000
<v Speaker 2>On a bust.

1286
01:14:52.720 --> 01:14:54.880
<v Speaker 4>Again, this goes back to sometimes you know, they are

1287
01:14:54.920 --> 01:14:58.000
<v Speaker 4>family members who are very supportive and understanding, and some

1288
01:14:58.479 --> 01:15:02.640
<v Speaker 4>who feel that the person it just doesn't work hard

1289
01:15:02.760 --> 01:15:08.079
<v Speaker 4>enough to control their behaviors. And that's if somebody with

1290
01:15:08.479 --> 01:15:12.399
<v Speaker 4>OCD it was so easy to just stop it, people

1291
01:15:12.439 --> 01:15:15.239
<v Speaker 4>would they wouldn't need treatment. So I think one of

1292
01:15:15.319 --> 01:15:18.880
<v Speaker 4>the mess is that it's a weakness. The other is

1293
01:15:19.000 --> 01:15:21.960
<v Speaker 4>I see it really as a brain based disorder. I mean,

1294
01:15:22.159 --> 01:15:26.079
<v Speaker 4>there's just so much evidence that this is the disorder

1295
01:15:26.119 --> 01:15:31.159
<v Speaker 4>of the brain, and it certainly has manifestations or behavioral

1296
01:15:31.760 --> 01:15:35.800
<v Speaker 4>but it's a brain based illness. And even the behavior

1297
01:15:35.960 --> 01:15:38.439
<v Speaker 4>therapy is acting to retrain the brain.

1298
01:15:39.119 --> 01:15:43.039
<v Speaker 1>Again, exposure and response prevention therapy. Huge, huge, huge love

1299
01:15:43.600 --> 01:15:46.039
<v Speaker 1>hate doing it, love that it's helped me so much.

1300
01:15:46.600 --> 01:15:49.239
<v Speaker 1>What do you feel is the hardest part about your job.

1301
01:15:51.079 --> 01:15:53.880
<v Speaker 4>The patients who don't get better? Yeah, I mean, and

1302
01:15:54.039 --> 01:15:56.359
<v Speaker 4>so I've never told the patient that I can't think

1303
01:15:56.399 --> 01:16:01.159
<v Speaker 4>of something else that we can do, and so I've

1304
01:16:01.199 --> 01:16:03.600
<v Speaker 4>always taken that position. I never give up on somebody.

1305
01:16:04.239 --> 01:16:08.560
<v Speaker 1>What about your favorite what's the most rewarding doing the deep.

1306
01:16:08.399 --> 01:16:12.319
<v Speaker 4>Brain stimulation and patients who have had OCD and for

1307
01:16:12.560 --> 01:16:16.479
<v Speaker 4>twenty years and within a few months they're back to

1308
01:16:16.560 --> 01:16:19.079
<v Speaker 4>living a normal life. It's just incredible.

1309
01:16:19.399 --> 01:16:22.000
<v Speaker 1>Do you ever cry about it? I'm about to start crying.

1310
01:16:22.119 --> 01:16:24.880
<v Speaker 4>No, I don't cry, you don't. But in the operating

1311
01:16:24.960 --> 01:16:27.640
<v Speaker 4>room it's interesting. So I mean again into detail, but

1312
01:16:27.760 --> 01:16:30.039
<v Speaker 4>we wake up the patients in the operating room to

1313
01:16:30.199 --> 01:16:34.600
<v Speaker 4>test the stimulation and sometimes you know what we look

1314
01:16:34.680 --> 01:16:38.039
<v Speaker 4>for is that they feel happy and when we turn

1315
01:16:38.119 --> 01:16:41.359
<v Speaker 4>on the stimulation. And we had one patient who in

1316
01:16:41.399 --> 01:16:44.439
<v Speaker 4>the middle of the operating room says, I feel happy.

1317
01:16:44.520 --> 01:16:46.159
<v Speaker 4>In fact, we asked her, what does it feel like?

1318
01:16:46.319 --> 01:16:49.880
<v Speaker 4>It feels like love in my chest for everyone else

1319
01:16:50.960 --> 01:16:53.640
<v Speaker 4>and almost everybody, maybe not me, start to tear up

1320
01:16:53.680 --> 01:16:56.560
<v Speaker 4>in the operating room, and she did very well. She

1321
01:16:56.680 --> 01:16:57.960
<v Speaker 4>went on to do very very well.

1322
01:16:58.279 --> 01:17:01.079
<v Speaker 1>Do you ever lie about crying? For example, right now.

1323
01:17:04.479 --> 01:17:06.720
<v Speaker 4>I'll cry sometimes the movies. I'm not a big crier.

1324
01:17:07.279 --> 01:17:10.319
<v Speaker 1>I'm crying about it. I don't even know this person. Well,

1325
01:17:10.960 --> 01:17:14.640
<v Speaker 1>the work you're doing so important, and it's really such

1326
01:17:14.720 --> 01:17:18.079
<v Speaker 1>a privilege to talk to you. Anyone who has knowledge

1327
01:17:18.119 --> 01:17:21.680
<v Speaker 1>of OCD is like, whoa, wait, good man, that's amazing,

1328
01:17:21.880 --> 01:17:24.119
<v Speaker 1>including me, So this is really cool.

1329
01:17:24.319 --> 01:17:26.479
<v Speaker 4>You know your stuff too, Ali, I'm impressed.

1330
01:17:26.920 --> 01:17:27.920
<v Speaker 1>Thank you so much for doing this.

1331
01:17:28.159 --> 01:17:29.199
<v Speaker 4>That's my pleasure.

1332
01:17:30.960 --> 01:17:34.319
<v Speaker 1>So consult an expert about your curiosities when it comes

1333
01:17:34.359 --> 01:17:38.399
<v Speaker 1>to getting treated. Please remember that an evaluation is really important.

1334
01:17:38.920 --> 01:17:42.920
<v Speaker 1>Some conditions look like others and they overlap and treatment

1335
01:17:42.960 --> 01:17:45.600
<v Speaker 1>can be really different. So find a specialist at the

1336
01:17:45.640 --> 01:17:48.199
<v Speaker 1>link in the show notes or on our website at

1337
01:17:48.279 --> 01:17:52.479
<v Speaker 1>aliward dot com, slash Ologies slash OCD Neurobiology, which we've

1338
01:17:52.520 --> 01:17:53.840
<v Speaker 1>also linked in the show notes, so you don't have

1339
01:17:53.880 --> 01:17:56.000
<v Speaker 1>to write that down right now now come back in

1340
01:17:56.039 --> 01:17:57.880
<v Speaker 1>a few days. Should be up this weekend for a

1341
01:17:57.960 --> 01:18:02.399
<v Speaker 1>bonus episode all about lived experience and more research and

1342
01:18:02.560 --> 01:18:05.199
<v Speaker 1>tips for loved ones and folks with OCD as I

1343
01:18:05.279 --> 01:18:09.039
<v Speaker 1>chat with researcher and OCD havever and mental health advocate

1344
01:18:09.319 --> 01:18:12.039
<v Speaker 1>Uma Chatterjee, who's amazing, And thank you so so much

1345
01:18:12.079 --> 01:18:15.039
<v Speaker 1>to doctor Wayne Goodman for the decades of tireless work

1346
01:18:15.159 --> 01:18:18.279
<v Speaker 1>to make this condition better understood and to improve the

1347
01:18:18.399 --> 01:18:20.760
<v Speaker 1>lives of people who have it, and for founding the

1348
01:18:20.960 --> 01:18:23.680
<v Speaker 1>International OCD Foundation, the charity of choice this week and

1349
01:18:23.840 --> 01:18:25.800
<v Speaker 1>we'll link them in the show notes as well. We're

1350
01:18:25.840 --> 01:18:28.159
<v Speaker 1>at Ologies on Blue Sky and Instagram. I'm at Aliward

1351
01:18:28.199 --> 01:18:31.239
<v Speaker 1>on both. We have weekly kid friendly episodes called Smologies

1352
01:18:31.359 --> 01:18:34.680
<v Speaker 1>available wherever you get podcasts. Just look for Asmologies, sm

1353
01:18:35.159 --> 01:18:39.359
<v Speaker 1>l O g I E S swear free shorter versions.

1354
01:18:39.680 --> 01:18:43.039
<v Speaker 1>Ologies Merch is available at ologiesmerch dot com, and to

1355
01:18:43.119 --> 01:18:45.680
<v Speaker 1>support the show and sending questions for upcoming episodes, you

1356
01:18:45.720 --> 01:18:49.039
<v Speaker 1>can sign up at Patreon dot com. Slash Ologies Aaron

1357
01:18:49.079 --> 01:18:52.880
<v Speaker 1>Talbert is our Ologies podcast Facebook admin Big Hugs to

1358
01:18:53.119 --> 01:18:55.720
<v Speaker 1>the whole Campbell Clan. This week a whale of a

1359
01:18:55.800 --> 01:18:59.199
<v Speaker 1>hug to Mike. Aveline Malick makes our professional transcripts. Kelly

1360
01:18:59.279 --> 01:19:01.239
<v Speaker 1>ar Dwyer does the Way Paige Noel Dilworth is our

1361
01:19:01.279 --> 01:19:04.640
<v Speaker 1>scheduling producer. Susan Hale managing directs the whole show. Jake

1362
01:19:04.720 --> 01:19:07.640
<v Speaker 1>Chafee is one wonderful editor and lead editor. Up top

1363
01:19:07.720 --> 01:19:10.600
<v Speaker 1>is Mercedes Maitland of Maitland Audio. Nick Thorburn wrote the

1364
01:19:10.640 --> 01:19:12.079
<v Speaker 1>theme music and if you stick around to the end

1365
01:19:12.119 --> 01:19:14.199
<v Speaker 1>of the episode, I tell you secret and if you

1366
01:19:14.279 --> 01:19:18.159
<v Speaker 1>heard the ADHD episodes. For a while, my chronic procrastination

1367
01:19:18.359 --> 01:19:21.359
<v Speaker 1>looked a lot like ADHD, and one doctor said it's possible.

1368
01:19:21.520 --> 01:19:24.319
<v Speaker 1>But a short trial of ADHD meds with me was

1369
01:19:24.399 --> 01:19:27.279
<v Speaker 1>like trying to coax a terrified chihuahua out from under

1370
01:19:27.319 --> 01:19:30.760
<v Speaker 1>a car by injecting it with espresso. Did not help me.

1371
01:19:31.159 --> 01:19:34.920
<v Speaker 1>Further evaluation revealed, hey, bitch, thinking NonStop that everyone might

1372
01:19:34.960 --> 01:19:37.840
<v Speaker 1>hate you because you made a minor mistake, and procrastinating

1373
01:19:37.960 --> 01:19:40.840
<v Speaker 1>to the point of panic because you're avoiding something so hard.

1374
01:19:41.159 --> 01:19:43.760
<v Speaker 1>We have a therapy for that. It's called exposure, and

1375
01:19:43.840 --> 01:19:46.239
<v Speaker 1>it will suck so hard, but then your brain will say, Okay,

1376
01:19:46.359 --> 01:19:49.479
<v Speaker 1>this is not so bad. It's like a jump from

1377
01:19:49.560 --> 01:19:53.039
<v Speaker 1>a high dive or a plunge into an ice bath.

1378
01:19:53.159 --> 01:19:56.439
<v Speaker 1>It is scary, it's not comfortable, it's not as bad

1379
01:19:56.479 --> 01:19:58.800
<v Speaker 1>as you thought, and then it's much easier to do

1380
01:19:59.119 --> 01:20:00.720
<v Speaker 1>the next time, and you'll be like, holy shit, I

1381
01:20:00.800 --> 01:20:03.920
<v Speaker 1>did that. So if you're listening to this because you

1382
01:20:04.119 --> 01:20:06.479
<v Speaker 1>have a loved one going through it, or you were,

1383
01:20:06.760 --> 01:20:09.520
<v Speaker 1>like me, diagnosed with OCD in the last couple of years,

1384
01:20:09.800 --> 01:20:12.119
<v Speaker 1>I hope you get it a little bit more. Let

1385
01:20:12.159 --> 01:20:15.760
<v Speaker 1>me tell you there are brighter days ahead. You got this. Also.

1386
01:20:15.840 --> 01:20:17.960
<v Speaker 1>The second secret is that sometimes I have a hard

1387
01:20:18.039 --> 01:20:19.880
<v Speaker 1>time not scrolling, and I don't get a lot of

1388
01:20:19.920 --> 01:20:21.960
<v Speaker 1>stuff done. And my friend Simone told me about this

1389
01:20:22.000 --> 01:20:25.119
<v Speaker 1>thing called a brick. It's like fifty bucks. It's a

1390
01:20:25.159 --> 01:20:28.039
<v Speaker 1>physical object you use to brick certain apps on your phone.

1391
01:20:28.279 --> 01:20:30.279
<v Speaker 1>You keep it on the fridge or somewhere that's not

1392
01:20:30.479 --> 01:20:34.159
<v Speaker 1>your hand. If Brick wants to advertise, I love them,

1393
01:20:34.199 --> 01:20:35.840
<v Speaker 1>but here I am just giving it to them for free.

1394
01:20:35.880 --> 01:20:37.880
<v Speaker 1>But yeah, this thing called a brick has helped me

1395
01:20:38.359 --> 01:20:41.199
<v Speaker 1>stop scrolling. So much when I'm avoiding things. Okay, I

1396
01:20:41.279 --> 01:20:43.920
<v Speaker 1>hope this episode helped in some way. Stay tuned. We're

1397
01:20:43.920 --> 01:20:45.279
<v Speaker 1>going to talk to um in a couple of days.

1398
01:20:45.720 --> 01:20:47.880
<v Speaker 1>That's a great combo too. Thank you for hearing about

1399
01:20:47.880 --> 01:20:50.680
<v Speaker 1>all of my mental health issues. I feel like we

1400
01:20:50.800 --> 01:20:54.439
<v Speaker 1>all have them. I just tell you about them. Well,

1401
01:20:54.479 --> 01:20:55.359
<v Speaker 1>I hope it helps, Okay.

1402
01:20:56.039 --> 01:21:09.119
<v Speaker 5>Where by pack Aderman's College, Homeology, crypto Zoology, Plethology, Technology, Meteorology, Fatology, Technology, Ceriology.

1403
01:21:08.960 --> 01:21:20.079
<v Speaker 6>Seminology, OCV soft flirt up get value.

1404
01:21:20.119 --> 01:21:22.439
<v Speaker 2>You can't argue with fat Tesco with their amazing club

1405
01:21:22.479 --> 01:21:25.520
<v Speaker 2>card prices. Serve up something special with our finest meal

1406
01:21:25.560 --> 01:21:28.199
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1407
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<v Speaker 2>for only sixteen euro like Succulent Board, be approved, Virushanger

1408
01:21:31.680 --> 01:21:34.520
<v Speaker 2>Strip loin Steaks with pepper, corn butter, or delicious Firous

1409
01:21:34.600 --> 01:21:37.960
<v Speaker 2>Chicken Parmeshama served with creamy potato gratam and our mix

1410
01:21:38.039 --> 01:21:42.479
<v Speaker 2>of rainbow root vegetables. And enjoy Goozillionaire or Salder Caramel cheesecake.

1411
01:21:42.680 --> 01:21:45.960
<v Speaker 2>Can't argue with that shop in store or online. Tesco.

1412
01:21:46.279 --> 01:21:48.720
<v Speaker 2>Every Little Helps available at most stores. Prices very in

1413
01:21:48.760 --> 01:21:49.119
<v Speaker 2>express
