Speaker 1: I'm sure we all have a little bit of fear
Speaker 1: factor as far as Alzheimer's disease goes. We've all seen
Speaker 1: patients fall into that category. Relatives, friends, neighbors, and you
Speaker 1: get so discouraged even trying to be around those people.
Speaker 2: Now, a new.
Speaker 1: Report comes out how a neurologist to use what he
Speaker 1: called precision lifestyle medicine to reverse early signs of Alzheimer's.
Speaker 1: He's suggesting we start much earlier. Stay tuned, we'll talk
Speaker 1: about this. Hi, and welcome to Health Talk with Doctor Lynn.
Speaker 1: Your daily dose. The information you hear on the show
Speaker 1: is informational. It's not meant to diagnose or treat any disease.
Speaker 1: Any kind of complete health conditions must be checked out
Speaker 1: and discussed with your primary care physicians.
Speaker 2: Get ready for the good news of the day.
Speaker 1: God bless you, folks, and.
Speaker 2: Here is doctor Lynn.
Speaker 1: Our daily devotional today comes from the Book of Ephesians,
Speaker 1: Chapter five. Find freedom through seeking to please me above
Speaker 1: all else. You can have only one master. When you
Speaker 1: let others expectations drive you, you scatter your energy to the winds.
Speaker 1: Your own desire to look good can also drain your energy.
Speaker 1: I am your master, and I do not drive you
Speaker 1: to be what you are not. Your pretense displeases me,
Speaker 1: especially when it's in my service. Concentrate on staying close
Speaker 1: to me at all times. It's impossible to be inauthentic
Speaker 1: while you are focusing on my presence. Oh that was good.
Speaker 1: Stay tuned, we'll talk about Alzheimer's seven nine one six
Speaker 1: four to reach me off air. It's funny because I'm
Speaker 1: right now in the middle of writing up an entire
Speaker 1: presentation I'll be doing in Pittsburgh for the professional training
Speaker 1: event Nutritional Frontiers dealing with brain functionality. I've been given
Speaker 1: a whole hour to discuss everything about the brain.
Speaker 2: Well, good luck with that. This new article that just came.
Speaker 1: Out this morning in the Journal of Dementia in Alzheimer's,
Speaker 1: said a neurologist used was called precision lifestyle medicine to
Speaker 1: reverse early Alzheimer's. A forty nine year old woman's memory
Speaker 1: loss had been reached the point where she placed a
Speaker 1: sticky note on the steering wheel of her car to
Speaker 1: reminder to drive on the right side of the road.
Speaker 1: As a jogger, she was used to keeping it left,
Speaker 1: and she had begun to confuse the two diagnosed with
Speaker 1: Alzheimer's related mild cognitive IMPAIRMID. She asked the neurologist for
Speaker 1: her as anything she could do to prevent further decline.
Speaker 2: He said, good luck with that.
Speaker 1: The idiot response is for most neurologists, it's unbelievable. The
Speaker 1: woman wasn't satisfied with that answer. She decided to try
Speaker 1: a precision medicine protocol and it worked for her.
Speaker 2: Over time or.
Speaker 1: Cognitive testing improved from below average the thirty fifth percentile
Speaker 1: to far above the ninety eighth percentile.
Speaker 2: Did you catch that?
Speaker 1: She is one of the patients featured in the case
Speaker 1: study published in the Journal of Biomedicines. Many people believe
Speaker 1: Alzheimer's disease is simply a matter of bad genes, bad luck,
Speaker 1: and inevitable consequences of aging, and once decline begins, nothing
Speaker 1: can be done. Doctor Dale Bredson, the lead author of
Speaker 1: the study internationally recognized neurologists specializing in neurodegenitive diseases, said
Speaker 1: the belief is outdated and that he has built a
Speaker 1: career trying to prove it, which more people understood that
Speaker 1: Alzheimer's disease is far more common than it needs to be.
Speaker 1: He believes precision medicine should be how the disease is approached.
Speaker 1: He describes a biological switch that moves the brain between
Speaker 1: what he calls connection mode and protection mode. When the
Speaker 1: brain is in connection mode, it can learn adapt in
Speaker 1: form memories. Alzheimer's, he said, develops when the brain shifts
Speaker 1: into protection mode, a shift that can be triggered by
Speaker 1: many different factors, including insulin resistance, sleep apnea, poor energy
Speaker 1: production at the cellular level, lack of exercise, chronic inflammation, infections,
Speaker 1: and exposure to toxins such as air pollution, heavy metals, microplastics.
Speaker 2: But that's all inclusive.
Speaker 1: We're addressing network insufficiency, he said, nothing by itself as
Speaker 1: a cure.
Speaker 2: It's like tuning up a car. You're changing multiple things
Speaker 2: to get.
Speaker 1: Them working together, so the body no longer needs to
Speaker 1: stay in protection mode and can return to connection mode.
Speaker 1: One reason why treatment for Alzheimer's disease has not been
Speaker 1: successful up till now, is that we have historically approached
Speaker 1: to Alzheimer's too narrowly.
Speaker 2: And too late.
Speaker 1: Focus needs to shift beyond amyloid in a variety of factors,
Speaker 1: from insulin resistance to nutrient efficiencies. These are not alternative
Speaker 1: medicine questions, but mainstream dementia risk factors. The growing recognition
Speaker 1: that Alzheimer's is a multifactorial disease has given rise to
Speaker 1: a precision medicine approach to treating it. Instead of giving
Speaker 1: everyone the same treatment, precision medicine takes a more personalized approach.
Speaker 1: Doctors consider the factors that may be affecting a person's
Speaker 1: brain health that put together a plan on that person's needs.
Speaker 1: In this study, researchers at wyl Cornell Medicine and New
Speaker 1: York Presbyterian used a precision medicine approach with people with
Speaker 1: Alzheimer's disease or mild cognitive impairment. Participants received a personalized
Speaker 1: program that included changes to their diet, exercise, sleep, stress
Speaker 1: management supplements in some cases medication. Most showed improvements or
Speaker 1: stabilization and cognitive function over the course of the study,
Speaker 1: along with improvements in several Alzheimer's related risk factors. His
Speaker 1: protocol is one example of what precision medicine can look
Speaker 1: like in practice. The goals to identify as many potential
Speaker 1: contribute to cognitive decline as possible. Protocol centers on a
Speaker 1: plant rich, mildly ketogenic, high fiber diet, leafy greens, non
Speaker 1: starchy vegetables, healthy fats, logallycemic foods. It encourages organic produce,
Speaker 1: wild caught, low mercury fish and pasteurized eggs and meat.
Speaker 1: Processed foods, refined carbs, artificial sweeteners, gluten containing foods, dairy,
Speaker 1: and alcohol are discouraged. People are encouraged to fast overnight
Speaker 1: for twelve to sixteen hours. This approach helps to support
Speaker 1: gut health, insulin sensitivity, metabolic flexibility, and ketone production. The
Speaker 1: brain needs a lot of power to function, he said.
Speaker 1: They can use gluten coses or ketones. Many people lack
Speaker 1: access to either because they're insulin resistant. Like every other
Speaker 1: aspect of the protocol, the dietary approach must be individualized,
Speaker 1: he said.
Speaker 2: For someone who's overweight.
Speaker 1: Fasting in ketosis may be easier because they have fat
Speaker 1: stores available to make ketones. For some frail however, the
Speaker 1: same approach may not be appropriate. Exercises, another core component protocol,
Speaker 1: includes aerobic exercise, strength training, balance work and stretching for
Speaker 1: at least forty five minutes per day, six days a week.
Speaker 1: Hormone levels and nutrient status including vitamin d bs, minerals,
Speaker 1: omega threes, thyroid function, and sex hormones are assessed and
Speaker 1: corrected where necessary. Stress management through biofeedback and heart rate
Speaker 1: variability training is also included. Once the brain's been better nourished,
Speaker 1: brain stimulation is also added. The last thing you want
Speaker 1: to do is work out with weights if you're malnourished.
Speaker 1: The same applies to the brain residence. Trials published in
Speaker 1: Journal Ofolzheimer's Disease tested as Precision Medicine approach twenty five
Speaker 1: people with mild cognitive impairment or dementia. Each person received
Speaker 1: personalized treatment in his most recent randomized controlled trial currently
Speaker 1: pending peer review, compared the standard care and people with
Speaker 1: mild cognitive impairment or early dementia. Standard care means participants
Speaker 1: continue to receive their usual treatment, usually managed with drugs
Speaker 1: that simply target symptoms from their healthcare providers. Fifty patients
Speaker 1: received the Precision medical protocol, twenty three receives standard care treatment.
Speaker 1: Cognitive testing was performed at the beginning of the study
Speaker 1: and again at three, six and nine months. Participants following
Speaker 1: the Precision Medicine protocol showed significant improvements in overall cognitive
Speaker 1: function memory in Alzheimer's symptoms. Severity provens were seen in
Speaker 1: blood pressure, body mass index, blood sugar control, lipid profiles,
Speaker 1: and other markers. The treatment effects size for overall cognitive
Speaker 1: function was calculated to be seven times greater than that
Speaker 1: reported in the trials for anti amyloid drugs such as
Speaker 1: lacanamap and don add and app got that overall function
Speaker 1: seven times greater than those high tech drugs that are
Speaker 1: multiple expense.
Speaker 2: Well.
Speaker 1: They've noted that precision medicine for Alzheimer's disease is an
Speaker 1: emerging field. She said that President's work offers an important
Speaker 1: shift in how the disease is understood and challenges the
Speaker 1: idea that Alzheimer's is a single pathway disease, even among
Speaker 1: those sympathetic to the protocol's goal. The practicality that portrays
Speaker 1: his questions. A nutritional functional practitioner by the name of
Speaker 1: Paul Aerons as a master personal trainer, said it's so
Speaker 1: full in regards to xerra azed commitment, and there are
Speaker 1: very few people can afford the time or the cost involved.
Speaker 2: What a negativity that was.
Speaker 1: Bresden acknowledges people don't need to do everything, he said.
Speaker 2: Who is this idiot, Paul ERNs.
Speaker 1: Ehr e n Forget it. We now have an option
Speaker 1: to not worry about Alzheimer's. If we do the right thing,
Speaker 1: this will become a scourge of the past. You make
Speaker 1: the call, need help with that, Give a call. Have
Speaker 1: a great day, folks.
Speaker 2: God