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<v Speaker 1>Joining me now is the CEO and the founder of

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<v Speaker 1>a company called Intrinsic Medicine. And when you hear what

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<v Speaker 1>they do, I bet you your first question is going

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<v Speaker 1>to be the same as mine, which is what Alex Martinez.

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<v Speaker 2>Welcome to the show. Hey Mandy, thanks for having me.

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<v Speaker 1>So what does Intrinsic Medicine? What are you guys investigating?

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<v Speaker 3>Basically, we believe that nature has already provided the solutions

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<v Speaker 3>to some of our most pressing problems today. And really

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<v Speaker 3>what we're trying to do is bring that back and

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<v Speaker 3>make it accessible with the body of scientific evidence. It

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<v Speaker 3>needs to be put into practice and put into real

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<v Speaker 3>use to help people improve their lives.

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<v Speaker 1>Now, you guys focus on gut health, and this is

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<v Speaker 1>something I've talked about quite a bit, and back in

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<v Speaker 1>four hundred BCE, Hippocrates believe that all gut, believe or

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<v Speaker 1>all health began on the gut. But you're specifically looking

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<v Speaker 1>at one thing in order to sort of heal the gun,

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<v Speaker 1>and that is human milk. Am I right here? What

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<v Speaker 1>what do you what is going on there?

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<v Speaker 2>Correct?

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<v Speaker 3>And and let me riff off of you there, Because

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<v Speaker 3>Havocrates knew what he was talking about, right and he said,

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<v Speaker 3>you know, all diseases start in the gut. And he

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<v Speaker 3>also said, let food be thy medicine. Yea as well.

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<v Speaker 3>So that gets us along the line of inquiry where wait,

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<v Speaker 3>what was okay? So food's medicine. Well, what's the first

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<v Speaker 3>human food? Oh, it's it's milk, milk from our mothers.

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<v Speaker 2>And what if we explore that?

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<v Speaker 3>And and we we look at it as not just food,

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<v Speaker 3>but we find components that are non caloric and lo

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<v Speaker 3>and behold we did, and there's there's fat in human milk,

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<v Speaker 3>there's there's lactose right freely available energy. But then there's

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<v Speaker 3>these compounds called human milk, oligo, sacrize, sugars, but they're

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<v Speaker 3>they're not digestible by a human being for clark energy,

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<v Speaker 3>So what are they doing? And and and that that

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<v Speaker 3>really is the line of inquiry that kind of led

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<v Speaker 3>to the programs that we're advancing for different purposes.

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<v Speaker 1>So I could hear a lot of people in my

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<v Speaker 1>listening audience going ah, and honestly, there's sort of this

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<v Speaker 1>vision of you guys with this group of lactation within producing, but.

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<v Speaker 2>That's not what this is at all.

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<v Speaker 1>So tell me about the actual substance that you guys

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<v Speaker 1>are using.

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<v Speaker 2>Ye, that's that's hilarious.

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<v Speaker 3>And look, let's what's hilarious is when we look back,

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<v Speaker 3>every civilization but ours has used actual human milk, this

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<v Speaker 3>scenario that you are describing for adult medicinal purposes. So

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<v Speaker 3>let's not forget that that history, let alone the body

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<v Speaker 3>builds who buy gray market donor milk.

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<v Speaker 1>God, that's so weird, right, I don't know why.

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<v Speaker 2>That's just weird to me.

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<v Speaker 1>But but I'm sorry I didn't many interrupt, let's continue,

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<v Speaker 1>go ahead, No, but.

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<v Speaker 3>But right, but it still gives us a vector that

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<v Speaker 3>there's something to this, right, And so like the line

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<v Speaker 3>that I want to put down is that milk is

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<v Speaker 3>for babies donor milk banks, that is for babies that

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<v Speaker 3>need it.

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<v Speaker 2>You know, when when my when my.

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<v Speaker 3>I know, among all people, how important is the breastfeed

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<v Speaker 3>and when my my wife had issues with it, like

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<v Speaker 3>we use donor milk and that was a blessing. And

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<v Speaker 3>so that's a resource that is for babies and should

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<v Speaker 3>never be diverted. So our compounds are produced with precision fermentation,

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<v Speaker 3>so they are nature identical. They do not take any

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<v Speaker 3>milk away from any baby They do not come from

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<v Speaker 3>any abreast there is there. They they are fermented. You know,

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<v Speaker 3>imagine you know, a brewpub, except instead of alcohol, you're

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<v Speaker 3>producing something that actually is foundational to human health.

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<v Speaker 1>Now, you guys are actually you have several sort of

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<v Speaker 1>pipeline things going on right now, and you're doing your

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<v Speaker 1>research in Australia. I'd like to kind of dip a

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<v Speaker 1>toe into why Australia makes it easier for you to

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<v Speaker 1>investigate some of these things, because in the case of this,

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<v Speaker 1>I'm guessing that your product, in even the limited sort

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<v Speaker 1>of research that you or the beginning of the pipeline

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<v Speaker 1>that you're in, probably doesn't have a lot of negative.

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<v Speaker 2>Side effects exactly.

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<v Speaker 3>And that's where there's a bit of a of a

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<v Speaker 3>paradox here in the United States because these compounds are

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<v Speaker 3>generally recognized as safe to be included in infant formula

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<v Speaker 3>right already, right to make it closer to human milk

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<v Speaker 3>and to provide the comprehensive spectrum of benefits to babies.

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<v Speaker 3>But the FDA considers these new drugs right, that's like

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<v Speaker 3>a big, long, expensive pathway. Australia has a much more

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<v Speaker 3>pragmatic one where they literally look at the same body

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<v Speaker 3>of evidence that we're looking at that supported inclusion in

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<v Speaker 3>infant formula, and they're like, yeah, this thing is super safe, right,

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<v Speaker 3>and it's likely to help these people, So they go

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<v Speaker 3>through a local institutional ethics approval process. So I mean,

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<v Speaker 3>these are this common sense, this fancy way of saying.

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<v Speaker 3>It's like looking at this in a very pragmatic aspect

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<v Speaker 3>and saying this is much more likely to help people

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<v Speaker 3>than to harm them, and it would be minimal at best.

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<v Speaker 3>Let's try it out and move it forward and get

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<v Speaker 3>an answer.

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<v Speaker 1>You have a study that seems to be the longest,

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<v Speaker 1>farthest along in the pipeline on Parkinson's disease. How are

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<v Speaker 1>you looking at different illnesses and positing that they could

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<v Speaker 1>be helped that specific illness. What made you say Parkinson's

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<v Speaker 1>may we may be able to do something here.

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<v Speaker 2>This is a great question.

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<v Speaker 3>Let's go back to the Hippocrates, you know quote right,

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<v Speaker 3>all diseases beginning the gut. And so we need to

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<v Speaker 3>start reframing our thinking that what we call individual diseases

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<v Speaker 3>are really kind of manifestations of a common biological dysregulation,

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<v Speaker 3>and it's dys biosis in the gut. And immune disregulation, right,

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<v Speaker 3>and there's different permutations and thus there are different manifestations

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<v Speaker 3>of what that looks like and how that impacts each

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<v Speaker 3>one of us as an individual, right, that's our individualized

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<v Speaker 3>dis ease. And so what we what we look for

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<v Speaker 3>is we look for like hardcore statistical correlations data and

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<v Speaker 3>one of the things in Parkinson's, So we already know

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<v Speaker 3>these compounds in adults.

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<v Speaker 2>Can they work amazing for IBS?

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<v Speaker 3>I'm an IBS patient myself, Like when I started syndrome, yeah,

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<v Speaker 3>rdable bowel syndrome. My philosophy was like, hey, you know what,

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<v Speaker 3>we would have awesome drugs if every CEO was required

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<v Speaker 3>to be like patient here, right, yeah, exactly, right, like

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<v Speaker 3>right right, we would have no side effects and everything

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<v Speaker 3>would be amazing. Right. So I lived it, and I've

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<v Speaker 3>been I've been taking this for five years and I've

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<v Speaker 3>I've constructively cured my IBS.

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<v Speaker 2>And that's like what gets me.

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<v Speaker 3>Up in the morning is saying, I can't be the

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<v Speaker 3>only one benefiting from this, and you know, and and

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<v Speaker 3>there's a clinical study that actually supports all of that.

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<v Speaker 2>But what we realized is because of the.

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<v Speaker 3>Safety of these compounds, that's that's that opportunity to get

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<v Speaker 3>to people in in diseases that typically no one thought

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<v Speaker 3>you could prevent, like parkinson Like how do you prevent Parkinson's?

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<v Speaker 3>And they have what's called prodromal symptoms. So these are

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<v Speaker 3>the ones that like happened like years sometimes decades before

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<v Speaker 3>the nerds degenerative, like the cognitive stuff happened, right, And

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<v Speaker 3>constipation is the biggest one if you have a prior

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<v Speaker 3>history and this was like there was a study it

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<v Speaker 3>was a couple of years ago, I think it was

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<v Speaker 3>in the British Medical Journal, and they looked like twenty

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<v Speaker 3>four thousand patients and if you had a prior history

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<v Speaker 3>of like chronic constipation or irritual bowel syndrome right consumption dominant,

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<v Speaker 3>your odds of getting Parkinson's were like four point one

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<v Speaker 3>one higher.

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<v Speaker 1>Wow, that's significant, Yeah, like four hundred and that's a lot.

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<v Speaker 1>I mean, well, so let me ask you this, how.

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<v Speaker 2>Far away are we?

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<v Speaker 1>And somebody asked on our text line on the Common

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<v Speaker 1>Spirit health text line we have here, Mandy, is this

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<v Speaker 1>the same as colostrum cow's milk now being sold for

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<v Speaker 1>health benefits like cowboy colostrum? Is this a similar thing

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<v Speaker 1>obviously you're talking human peptides or human that's the wrong word.

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<v Speaker 3>But yeah, this is a different component and and and

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<v Speaker 3>I know, like so colostrum has is proteins. Think about

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<v Speaker 3>like those are proteins and those are like soluble antibodies.

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<v Speaker 2>Okay, okay, So how far away from we.

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<v Speaker 1>Are we from having a product or a drug that

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<v Speaker 1>people can actually use that that you know, if it

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<v Speaker 1>does prove to be successful.

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<v Speaker 2>What are we looking at in years? Yeah?

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<v Speaker 3>So this is where I'm going to do something a

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<v Speaker 3>little bit different because I actually my patience is up.

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<v Speaker 3>I'm doing the formal drug development process, yes, but we're

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<v Speaker 3>starting a separate entity that actually can make these available

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<v Speaker 3>today as.

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<v Speaker 1>A nutritional supplement.

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<v Speaker 2>Yeah. Yeah, well yeah, yeah, I mean.

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<v Speaker 1>I mean, I hate to say it, but our we

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<v Speaker 1>can have a whole conversation Alex on our FDA and

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<v Speaker 1>the way stuff is approved in this country. I think

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<v Speaker 1>that's kind of cool. I'd love to have you back

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<v Speaker 1>on because we're out of time now. When you when

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<v Speaker 1>you've got that out, I got a lot of people saying, Okay,

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<v Speaker 1>I'm ready, where can I find this? So let's touch

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<v Speaker 1>back when you have that going and when it comes

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<v Speaker 1>to supplement that people can buy.

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<v Speaker 2>Alex.

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<v Speaker 3>Yeah, yeah, that'll be working on that like today. So

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<v Speaker 3>so this is this is a wonderful conversation. Thank you

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<v Speaker 3>for having me.

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<v Speaker 2>It's fascinating.

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<v Speaker 1>I mean, I long believe that food is medicine and

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<v Speaker 1>that you know, if you feed your body right, you're

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<v Speaker 1>gonna feel a million times better.

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<v Speaker 2>So this tracks with that.

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<v Speaker 3>Diverse fiber everyone get it. Just eat it, like, get

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<v Speaker 3>get your you know, go out and nature, be around children, like, oh, to.

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<v Speaker 1>Get your diseases, to get your germ hits.

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<v Speaker 3>Is that what we're doing, To get your germ hits,

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<v Speaker 3>but also to get your biffidobacterium right because right families

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<v Speaker 3>and people, their microbiomes converge, and so you have a

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<v Speaker 3>more youthful microbiome if you are around younger people.

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<v Speaker 2>Oh that's interesting.

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<v Speaker 3>Yeah, and then you and then you feed it with

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<v Speaker 3>healthy fibers and you can you can nurture it. And again,

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<v Speaker 3>just go out look socially and you'll see it in action.

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<v Speaker 2>You'll see it in principle.

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<v Speaker 1>Intrinsicmedicine dot com is their website. Alex Martinez, thanks for

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<v Speaker 1>your time today.

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<v Speaker 2>I appreciate it.